Results 81 to 90 of about 23,244 (239)

Circ_101341 Deteriorates the Progression of Clear Cell Renal Cell Carcinoma Through the miR- 411/EGLN3 Axis

open access: yesCancer Management and Research, 2020
Yongjun Yue,1 Jinsheng Cui,1 Yu Zhao,2 Shangying Liu,3 Weixing Niu1 1Department of Urology, Heji Hospital, Changzhi Medical College, Changzhi, Shanxi 046000, People’s Republic of China; 2Department of Ophthalmology, Peace Hospital, Changzhi Medical
Yue Y, Cui J, Zhao Y, Liu S, Niu W
doaj  

Establishment of Sunitinib-Resistant Xenograft Model of Renal Cell Carcinoma and the Identification of Drug-Resistant Hub Genes and Pathways

open access: yesDrug Design, Development and Therapy, 2021
Yingwei Xie,1,2,* Wentai Shangguan,1,2,* Zhiliang Chen,1,2,* Zaosong Zheng,3 Yuqing Chen,4 Qiyu Zhong,1,2 Yishan Zhang,1,2 Jingying Yang,1,2 Dingjun Zhu,1,2,5 Wenlian Xie1,2,5 1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen
Xie Y   +9 more
doaj  

M2 macrophages secrete CXCL13 to promote renal cell carcinoma migration, invasion, and EMT

open access: yesCancer Cell International, 2021
Objective M2 macrophages are associated with a poor prognosis in a variety of malignancies. There are, however, few relevant investigations in clear cell renal cell carcinoma (ccRCC).
Yingwei Xie   +9 more
doaj   +1 more source

Tumor-Infiltrated CD8+ T Cell 10-Gene Signature Related to Clear Cell Renal Cell Carcinoma Prognosis

open access: yesFrontiers in Immunology, 2022
Clear cell renal cell carcinoma (ccRCC) usually affects multiple organs (e.g., bone and brain), and patient prognosis is usually poor. Although it is known that CD8+ T cell infiltration can potentially alleviate ccRCC progression, few studies have ...
Jie Wang   +14 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Efficacy of 8-chloroadenosine in ccRCC cell lines.

open access: yes, 2015
a. ccRCC cell lines treated with 20 μM or 80 μM 8-chloroadenosine for 7 days. b. Cell cycle analysis of ccRCC cell lines treated with 40 μM 8-chloroadenosine for 48 hours. c. IC50 values of ccRCC cell lines calculated in Calcusyn software.
Amado J. Zurita (270090)   +6 more
core   +1 more source

Fatty acid metabolism reprogramming in ccRCC: mechanisms and potential targets

open access: yes, 2023
Lipid droplet formation is a defining histological feature in clear-cell renal cell carcinoma (ccRCC) but the underlying mechanisms and importance of this biological behaviour have remained enigmatic.
Welford, Scott M   +4 more
core   +1 more source

miR-758-3p Inhibits Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma and Predicts Favorable Prognosis

open access: yesCancer Management and Research, 2020
Yao Wu,1 Yan Liu2 1Endoscopy Center, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning 121000, People’s Republic of China; 2Department of Urology Surgery, The First Affiliated Hospital of Jinzhou Medical University ...
Wu Y, Liu Y
doaj  

KMT5C‐Mediated H4K20me3 Recruits EWSR1 to Propel Clear Cell Renal Cell Carcinoma Progression via Regulating ACADM Transcription and m6A Modification

open access: yesMed Research, EarlyView.
A schematic diagram illustrating the KMT5C‐H4K20me3‐EWSR1‐ACADM signaling axis and its role in ccRCC progression. Key Outcomes: KMT5C/H4K20me3 are upregulated in ccRCC and predict poor prognosis. EWSR1 is a novel noncanonical H4K20me3 reader in ccRCC. KMT5C/EWSR1 co‐repress ACADM via transcription and m6A modification. A‐196 + sunitinib synergistically
Chengjian Ji   +10 more
wiley   +1 more source

The m6A modification-mediated OGDHL exerts a tumor suppressor role in ccRCC by downregulating FASN to inhibit lipid synthesis and ERK signaling

open access: yesCell Death and Disease, 2023
Metabolic reprogramming is a hallmark of cancer, and the impact of lipid metabolism as a crucial aspect of metabolic reprogramming on clear cell renal cell carcinoma (ccRCC) progression has been established.
Jian Shi   +8 more
doaj   +1 more source

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