Results 81 to 90 of about 9,624 (181)

BAP1 complexes with YY1 and RBBP7 and its downstream targets in ccRCC cells

Open Life Sciences
Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer. A few genes, such as BAP1, are associated with the tumorigenesis of ccRCC. Mutations in BAP1 are related to a proportion of ccRCCs. In this study, to explore the functional
Wu Ying, Li Xue-Ying, Chen Jin-Dong, Pan You-Fu   +3 more
doaj   +1 more source

Long Non-Coding RNA LUCAT1 Promotes Proliferation and Invasion in Clear Cell Renal Cell Carcinoma Through AKT/GSK-3β Signaling Pathway

Cellular Physiology and Biochemistry, 2018
Background/Aims: Long non-coding RNAs (lncRNAs) have emerged as new regulators and biomarkers in several cancers. However, few lncRNAs have been well characterized in clear cell renal cell carcinoma (ccRCC). Methods: We investigated the lncRNA expression
Zaosong Zheng, Fengjin Zhao, Dingjun Zhu, Jinli Han, Haicheng Chen, Yuhong Cai, Zhiliang Chen, Wenlian  Xie   +7 more
doaj   +1 more source

CD248 Expression in Clear Cell Renal Cell Carcinoma and Its Clinical Significance

Zhongliu Fangzhi Yanjiu, 2020
Objective To investigate the expression of CD248 (endosialin) in clear cell renal cell carcinoma (ccRCC) tissues and its clinical significance. Methods We collected fresh specimens from 17 ccRCC tissues and adjacent tissues, as well as paraffin specimens
HU Wei, ZHU Hengcheng, LI Haoyong, LIU Xiuheng, ZENG Yan   +4 more
doaj   +1 more source

ADAM19 Promotes EMT‐Related Changes and Serves as a Prognostic Marker in Circulating Tumor Cells of Renal Cell Carcinoma

Cancer Science, EarlyView.
ADAM19 is associated with EMT‐related malignant phenotypes and NOTCH/NF‐κB pathway activity in RCC and may serve as a prognostic biomarker in CTCs. ABSTRACT Detection of circulating tumor cells (CTCs), particularly characterization of their epithelial‐mesenchymal transition (EMT) phenotypes, may improve prognostic accuracy for malignancies ...
Minxin He, Mingrui Li, Yifei Ma, Zhenzhuo Chen, Lingyu Guo, Xiangyu Wang, Wenjing Wang, Tie Chong, Zhenlong Wang   +8 more
wiley   +1 more source

Characterization of PBRM1 in ccRCC cells.

, 2016
(A) Relative transcript expression of PBRM1 in ccRCC cell lines. (B) Protein levels of BRG1 and PBRM1 in ccRCC cell lines. (C) Characterization of deletion in exon 17 of PBRM1 gene in Caki2 cells.
Emily C. Dykhuizen (2400376), Matthew J. Schipma (2621923), Basudev Chowdhury (2182760), Christina R. Ferreira (461379), Elizabeth G. Porter (2041459), Jane C. Stewart (2621920)   +5 more
core   +1 more source

DataSheet_4_Cuproptosis in ccRCC: key player in therapeutic and prognostic targets.zip

, 2023
BackgroundClassical biomarkers have been used to classify clear cell renal cell carcinoma (ccRCC) patients in a variety of ways, and emerging evidences have indicated that cuproptosis is closely related to mitochondrial metabolism, thereby accelerating ...
Shaohua He (13202703), Chao Qin (119135), Zhongwen Lu (10134056), Qiang Li (8118), Hongqi Chen (425987), Yang Lv (279176), Lu Yin (183747)   +6 more
core   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Immunohistochemical staining for KCa3.1 in ccRCC and oncocytoma.

, 2015
Immunohistochemical staining for KCa3.1 in ccRCC (A) and oncocytoma (B) shows strong staining of tumor vessels (long arrows) in both tumor subtypes.
Ralf Köhler (34264), Maj Rabjerg (127189), Niels Marcussen (497185), Linda Sevelsted-Møller (718407), Boye L. Jensen (718409), Lars Koch Hansen (718406), Steen Walter (718408), Aida Oliván-Viguera (127186), Line Jensen (109124)   +8 more
core   +1 more source

Table_1_Establishment of a ccRCC patient-derived chick chorioallantoic membrane model for drug testing.DOCX

, 2022
Clear cell renal cell carcinoma (ccRCC) is an aggressive subtype of renal cell carcinoma accounting for the majority of deaths in kidney cancer patients.
Nadia Ekindi-Ndongo (13913580), Kelly Harper (190457), Claudio Jeldres (13913583), Claire M. Dubois (8300340), Karine Brochu-Gaudreau (190442), Patrick P. McDonald (3121830), Martine Charbonneau (279930), Alexis Perreault (13913577)   +7 more
core   +1 more source

Experiment‐Anchored Abundance–Coverage Frontiers Define Conditional RHSVV Exposure Requirements in TP53‐Missense Tumors

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Mutant p53 accumulation may complement conformation‐sensitive RHSVV recognition, but the required exposure discrimination depends on tumor coverage and normal‐cell stress. We analyzed 809 tumors and 523 adjacent‐normal specimens from eight CPTAC cohorts.
Takehiro Ishikawa
wiley   +1 more source