Results 101 to 110 of about 23,244 (239)
Molecular Cancer, 2019 Background Circular RNA (circRNA) is a type of circular endogenous RNA produced by special selective splicing and participates in progression of diverse diseases.
Dingwei Xue +10 more
doaj +1 more source
Histopathology, Volume 89, Issue 4, Page 574-589, October 2026.New concepts, innovations and some issues have emerged since the adoption a decade ago of WHO/ISUP grading for CCRCC and PRCC. Continued use of the WHO/ISUP grading for CCRCC and PRCC has been upheld by newer studies, and practice guidance for some of the grading issues, where data are available, is provided.
Gladell P. Paner +4 more
wiley +1 more source
BMAL1-HIF2α heterodimers contribute to ccRCC
Abstract Circadian disruption enhances cancer risk, and many tumors exhibit disordered circadian gene expression. We show rhythmic gene expression is unexpectedly robust in clear cell renal cell carcinoma (ccRCC). Furthermore, the clock gene BMAL1 is higher in ccRCC than in healthy ...
Katja A Lamia +8 more
openaire +3 more sources
BJUI Compass, Volume 7, Issue 9, September 2026.Abstract Objective The aim of this study was to evaluate the diagnostic yield and downstream clinical impact of routine preoperative chest CT in patients undergoing partial nephrectomy (PN) for localized renal cell carcinoma. Methods We conducted a retrospective multicentre study using data from the French Urological Cancer Comprehensive Cohort (UroCCR)
Ali Bourgi +33 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 9, September 2026.ABSTRACT Background Predicting clear cell renal cell carcinoma (ccRCC) pathological grade preoperatively is critical for clinical management. This study aims to evaluate the diagnostic accuracy and clinical utility of machine learning (ML)‐based imaging models.
Yuchao Wang +13 more
wiley +1 more source
Immunohistochemical staining for CD31 in ccRCC and oncocytoma.
, 2015 Immunohistochemical staining for CD31 in ccRCC (A) and oncocytoma (B) showed no difference in microvessel density between the two tumor subtypes (C). Note that the unaffected cortex from ccRCC patients contained more CD31-positive blood vessels while the
Ralf Köhler (34264) +8 more
core +1 more source
Study on the mechanism of BGN in progression and metastasis of ccRCC
BMC Medical GenomicsTo investigate the role of Biglycan(BGN) in the progression and metastasis of clear cell renal cell carcinoma(ccRCC).Based on multiple public databases, we investigated the expression level of BGN in ccRCC, its clinical significance, and its association with immune cells.
Hanqing Xia +12 more
openaire +3 more sources
Identification of key genes of the ccRCC subtype with poor prognosis
Scientific Reports, 2022 AbstractClear cell renal carcinoma has been reported in many research studies as a rather heterogeneous disease. Identification of different subtypes and their molecular characteristics can help in choosing a more effective treatment and predicting a response to it. In this study, using multi-omics clustering of RNA-Seq data of patients with clear cell
openaire +3 more sources
Cancer Medicine, Volume 15, Issue 9, September 2026.ABSTRACT Background TFE3‐rearranged renal cell carcinoma (TFE3‐rRCC) is uncommon and encompasses biologically diverse tumors, while evidence to guide systemic treatment remains sparse. We examined clinical outcomes, treatment patterns, and molecular features in a multicenter real‐world cohort.
Shuxuan Zhu +20 more
wiley +1 more source
Upsala Journal of Medical SciencesObjectives: This study aimed to determine the effects of von Hippel–Lindau protein (VHL) expression on hypoxia-inducible factor (HIF) and E-cadherin proteins.
Raviprakash T. Sitaram, Börje Ljungberg
doaj +1 more source