Results 101 to 110 of about 9,624 (181)

Correlation between ZHX1 expression and clinical characteristics in ccRCC.

, 2017
Correlation between ZHX1 expression and clinical characteristics in ccRCC.
Ryuk-Jun Kwon (555308), Dae Cheon Jeong (3713122), Ji-Young Kim (509387), Liangwen Liu (3343916), Sae-Ock Oh (318957), Yun Hak Kim (442940), Myoung-Eun Han (318943), Jin-Sup Jung (3343913)   +7 more
core   +1 more source

DataSheet_1_Cuproptosis in ccRCC: key player in therapeutic and prognostic targets.zip

, 2023
BackgroundClassical biomarkers have been used to classify clear cell renal cell carcinoma (ccRCC) patients in a variety of ways, and emerging evidences have indicated that cuproptosis is closely related to mitochondrial metabolism, thereby accelerating ...
Shaohua He (13202703), Chao Qin (119135), Zhongwen Lu (10134056), Qiang Li (8118), Hongqi Chen (425987), Yang Lv (279176), Lu Yin (183747)   +6 more
core   +1 more source

Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu, Lei Wu, Kang Yang, Kang Xie, Tao Lu, Tiangxiang Huang, Dengfeng Wan, Tao Song, Longbo Zhang   +8 more
wiley   +1 more source

BMAL1-HIF2α heterodimers contribute to ccRCC

Abstract Circadian disruption enhances cancer risk, and many tumors exhibit disordered circadian gene expression. We show rhythmic gene expression is unexpectedly robust in clear cell renal cell carcinoma (ccRCC). Furthermore, the clock gene BMAL1 is higher in ccRCC than in healthy ...
Katja A Lamia, Rebecca Mello, Diego Gomez Ceballos, Colby Sandate, Daniel Agudelo, Celine Jouffe, Nina Uhlenhaut, Nicolas Thoma, M.Celeste Simon   +8 more
openaire   +3 more sources

Study on the mechanism of BGN in progression and metastasis of ccRCC

BMC Medical Genomics
To investigate the role of Biglycan(BGN) in the progression and metastasis of clear cell renal cell carcinoma(ccRCC).Based on multiple public databases, we investigated the expression level of BGN in ccRCC, its clinical significance, and its association with immune cells.
Hanqing Xia, Tianzhen He, Xueyu Li, Kai Zhao, Zongliang Zhang, Guanqun Zhu, Han Yang, Xuechuan Yan, Qinglei Wang, Zhaofeng Li, Zaiqing Jiang, Ke Wang, Xinbao Yin   +12 more
openaire   +3 more sources

Dysregulation of the miR-25-IMPA2 axis promotes metastatic progression in clear cell renal cell carcinomaResearch in context

EBioMedicine, 2019
Background: The molecular mechanism underlying clear cell renal cell carcinoma (ccRCC) metastasis remains unclear. We therefore aimed to elucidate the role of IMPA2 in ccRCC metastatic progression.
Yuh-Feng Lin, Jian-Liang Chou, Jeng-Shou Chang, I-Jen Chiu, Hui-Wen Chiu, Yuan-Feng Lin   +5 more
doaj   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, Volume 117, Issue 11, Page 2910-2923, November 2026.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source

pVHL status in clear cell renal cell carcinoma regulates HIF-α and E-cadherin expression levels and their implications for tumor progression

Upsala Journal of Medical Sciences
Objectives: This study aimed to determine the effects of von Hippel–Lindau protein (VHL) expression on hypoxia-inducible factor (HIF) and E-cadherin proteins.
Raviprakash T. Sitaram, Börje Ljungberg
doaj   +1 more source

Immunohistochemical staining for CD31 in ccRCC and oncocytoma.

, 2015
Immunohistochemical staining for CD31 in ccRCC (A) and oncocytoma (B) showed no difference in microvessel density between the two tumor subtypes (C). Note that the unaffected cortex from ccRCC patients contained more CD31-positive blood vessels while the
Ralf Köhler (34264), Maj Rabjerg (127189), Niels Marcussen (497185), Linda Sevelsted-Møller (718407), Boye L. Jensen (718409), Lars Koch Hansen (718406), Steen Walter (718408), Aida Oliván-Viguera (127186), Line Jensen (109124)   +8 more
core   +1 more source

Sequence identification of the three ccRCC serum protein biomarkers.

, 2014
Sequence identification of the three ccRCC serum protein biomarkers.
Yan Gao (93649), Jin Yang (86490), Liying Liu (132271), Xiaofei Wang (135107), Yannan Qin (125322), Juan Yang (384075), Chen Huang (202847), Tusheng Song (654368), Lingyu Zhao (654367)   +8 more
core   +1 more source