Results 111 to 120 of about 94,671 (230)
Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos +3 more
wiley +1 more source
CD1 molecules: Beyond antigen presentation
CD1 molecules are well known for their role in binding and presenting lipid antigens to mediate the activation of CD1-restricted T cells. However, much less appreciated is the fact that CD1 molecules can have additional "unconventional" roles which impact the activation and functions of CD1-expressing cells, ultimately controlling tissue homeostasis as
Evans, Lauren, Barral, Patricia
openaire +2 more sources
Persisting Disadvantages: A Study of the Dynamics of Cumulative Deprivation
ABSTRACT Identifying populations at risk of deprivation is crucial for effective policy design. Yet, much existing research focuses on single aspects, such as income or material deprivation, and often abstracts from deprivation dynamics. This study addresses this gap by analyzing the dynamics and socio‐economic gradient of cumulative deprivation using ...
Santiago Budría +1 more
wiley +1 more source
An overlap between proteomic and transcriptomic findings in experiments testing brain responses to glucocorticoids. A shows that 455 proteins responsive to glucocorticoids were not confirmed at the transcriptomic level while 4 proteins were matched with significant differences in mRNA in all 8 datasets derived from transcriptomic experiments.
Grzegorz R. Juszczak
wiley +1 more source
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava +7 more
wiley +1 more source
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister +14 more
wiley +1 more source
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling +17 more
wiley +1 more source
Recent Advances in Nanomaterial‐Based Light Conversion for Agriculture
This figure illustrates three applications of nanophotoconversion materials for enhanced plant photosynthesis. These materials can directly target plant photosynthetic organs or be integrated into supplemental lights to optimize spectra. They can also be used in agricultural films to regulate sunlight for precise light control in protected agriculture.
Ting Tang +4 more
wiley +1 more source
This review maps how electroenzymatic cascades that couple nitrogen‐cycle enzymes with C─N bond forming auxilary enzymes, powered by direct electron transfer (DET) or mediated electron transfer (MET), can upgrade N2 and waste nitrogen streams into value‐added amines, amides, amino acids, and other nitrogen‐based chemicals.
Rohit G. Jadhav +4 more
wiley +1 more source
Zone Matcher: A climate‐based web application for deployment and assisted migration of forest trees
Abstract Populations of forest trees are generally adapted to the climates they inhabit. The farther trees are moved from their local climates, the more long‐term growth and survival tend to decrease. Current tree deployment and assisted migration rely on “climate distance thresholds” (CDTs), which are climatic distances beyond which tree performance ...
Tal J. Shalev +6 more
wiley +1 more source

