Results 131 to 140 of about 51,555 (247)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, Volume 20, Issue 10, Page 2410-2423, October 2026.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Novel Al(OH)3 and Ti/Fe@Al(OH)3 nano catalyzed of N-(3-((E)-3-(4-Adamant-1-yl)-phenyl) acryloyl) phenyl) quinoline-2-carboxamide Synthesis and its Molecular Docking, Quantum chemical Studies

Chemical Physics Impact
Using a green chemical Al(OH)3 and Ti/Fe@Al(OH)3 nanocatalyzed method, a number of new adamantyl substituted quinoline based chalcone derivative 1 to chalcone derivative 4 (CD1 to CD4) have been synthesized.
C. Thirumurugan, R. Thirumalaisamy, A. Lalitha, P. Vadivel, R․Selva Kumar, Kalandar Ameer, Ramalingam Karthik Raja, Shyam Kumar Rajaram, Ponmurugan Karuppiah   +8 more
doaj   +1 more source

Lab‐in‐a‐Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme‐Functionalized Beads for Diagnosis of Clostridioides difficile Infection

Advanced Materials, Volume 38, Issue 56, 8 October 2026.
The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena, Soyeon Lee, Youngeun Choi, Jonathan L'Heureux‐Hache, Jiaying Liu, Sadman Sakib, Sara M. Imani, Marek Smieja, Yingfu Li, Todd Hoare, Leyla Soleymani   +10 more
wiley   +1 more source

Effects of a Western Diet on Colonic Dysbiosis, Bile Acid Dysmetabolism and Intestinal Inflammation in Clinically Healthy Dogs

Journal of Veterinary Internal Medicine
Background Consumption of a high‐fat, high‐carbohydrate Western‐style diet (WD) associated with obesity and inflammation in humans has not been investigated in dogs.
Brandon Mason, Dipak Kumar Sahoo, Chelsea A. Iennarella‐Servantez, Aarti Kathrani, Shannon M. Morgan, Agnes Bourgois‐Mochel, Alex M. Bray, Vojtech Gabriel, Christopher Zdyrski, Jennifer M. Groeltz, Eric Cassmann, Mark R. Ackermann, Jan S. Suchodolski, Jonathan P. Mochel, Karin Allenspach, Albert E. Jergens   +15 more
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Carbon Dots With Concurrently Tunable Photoluminescence and Nanozyme Activity for Agricultural Stress Resistance: A Carbonization Degree‐Mediated Strategy

Aggregate, Volume 7, Issue 10, October 2026.
Carbonization degree is established as a unified structural parameter that synergistically governs the photoluminescence and SOD‐like activity of CDs. Progressive carbonization generates sp2‐conjugated domains where edge‐site carbonyl groups act as catalytic sites for SOD‐like activity.
Yunge Tang, Yue Zhang, Xin Peng, Xinyuan Wang, Pengpeng Wang, Kang Sun, Lei Han, Siyu Lu, Xiaokai Xu   +8 more
wiley   +1 more source

Cellular endocytic compartment localization of expressed canine CD1 molecules

, 2016
CD1 molecules are glycoproteins present primarily on dendritic cells (DCs), which recognize and presenta variety of foreign- and self-lipid antigens to T-cells.
Mette Schjaerff, Moore, Peter F., Peter F. Moore, Keller, Stefan M., Stefan M. Keller, Kristensen, Annemarie Thuri, Verena K. Affolter, Annemarie T. Kristensen, Affolter, Verena K., Schjærff, Mette   +9 more
core   +1 more source

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

Annals of Neurology, Volume 100, Issue 4, Page 808-823, October 2026.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello, Mario Picozza, Gisella Guerrera, Silvia Corbisiero, Andrea Misiti, Roberta C. Placido, Alice Verdiani, Lorenzo de Marco, Manolo Sambucci, Elena Olivieri, Daniela F. Angelini, Esmeralda Quartuccio, Luca Prosperini, Carla Tortorella, Maria C. Buscarinu, Valeria Zancan, Francesca de Masi, Marco Salvetti, Claudio Gasperini, Giovanna Borsellino, Luca Battistini   +20 more
wiley   +1 more source

A systematic review and meta‐analysis on the safety and efficacy of Aquablation

BJUI Compass, Volume 7, Issue 10, October 2026.
Abstract Objectives This work aimed to evaluate the efficacy and safety of Aquablation for the treatment of benign prostatic enlargement. Methods A systematic review was conducted in accordance with PRISMA 2020 guidelines (PROSPERO CRD420261401865). A comprehensive PubMed search identified prospective studies and randomised controlled trials published ...
Kimberley Chan, Nico Christian Grossmann, Matthew Feyissa, Jeremy Nettleton, Philip Charlesworth, Neil Barber, Jeremy Teoh, Ben Challacombe, Garrett Pohlman, Evangelos Liatsikos, Dean Elterman, Nikhil Vasdev   +11 more
wiley   +1 more source

Phase transitions in magnetic semiconductors Cd1−xMnxGeAs2 and Cd1−xCrxGeAs2 at hydrostatic pressure up to 9 GPa

, 2005
Измерена температурная зависимость удельного электросопротивления и коэффициента Холла при атмосферном давлении в температурном интервале 77–420 K на новых магнитных полупроводниках Cd1−xMnxGeAs2 с различным содержанием марганца (х = 0.06 и 0.18).
Михайлов, С.Г., Камилов, И.К., Залибеков, У.З., Маренкин, С.Ф., Магомедов, А.Б., Моллаев, А.Ю., Новоторцев, В.М., Арсланов, Р.К.   +7 more
core   +1 more source