Results 61 to 70 of about 48,670 (240)

Features of the CD1 gene family in rodents and the uniqueness of the immune system of naked mole-rat

Biology Direct
Cluster of Differentiation 1 (CD1) proteins are widely expressed throughout jawed vertebrates and present lipid antigens to specific CD1-restricted T lymphocytes.
Konstantin V. Gunbin, Gelina S. Kopeina, Boris Zhivotovsky, Alexey V. Zamaraev   +3 more
doaj   +1 more source

Effect of Cd1-xMnxSe Alloy Thickness on the Optical and Photovoltaic Properties of Quantum Dot-Sensitized Solar Cells

Frontiers in Materials, 2019
In this work, the Cd1−xMnxSe alloy was successfully prepared using a successive ionic layer adsorption and reaction method to investigate the layers' effect on the properties of devices while concentration dopant was optimized at 20% (molar ...
Ha Thanh Tung, Dang Huu Phuc, Dang Huu Phuc   +2 more
doaj   +1 more source

The small molecule simufilam dose‐dependently attenuates the worsening of seizures in a mouse model of tuberous sclerosis complex

Epilepsia, EarlyView.
Abstract Objective Novel epilepsy treatments for patients with tuberous sclerosis complex (TSC) and focal cortical dysplasia type II (FCDII) are urgently needed. In these patients, mutations in the mechanistic target of rapamycin (mTOR) pathway genes lead to mTOR hyperactivity and focal cortical malformations that frequently cause intractable epilepsy ...
Branden Stansley, Md. Monirul Islam, Dean J. Aguiar, Zoë Fuchs, Mackenzie Catron, Stephen Morairty, Ying Yuan, Radleigh Santos, Jingguo Hou, Annelies de Kater, George B. Thornton, Angelique Bordey   +11 more
wiley   +1 more source

CD1- and CD1+ porcine blood dendritic cells are enriched for the orthologues of the two major mammalian conventional subsets

, 2019
Conventional dendritic cells (cDC) are professional antigen-presenting cells that induce immune activation or tolerance. Two functionally specialised populations, termed cDC1 and cDC2, have been described in humans, mice, ruminants and recently in pigs ...
Soldevila, F, Crooke, HR, Mokhtar, H, Steinbach, Falko, Marchi, E, Edwards, JC, Johns, HL, Pedrera, M, Kaveh, DA, Nunez-Garcia, J, Everett, HE, Hogarth, PJ, Graham, Simon   +12 more
core   +1 more source

Role of lipid transfer proteins in loading CD1 antigen-presenting molecules

Journal of Lipid Research, 2018
Research to connect lipids with immunology is growing, but details about the specific roles of lipid transfer proteins (LTPs) in antigen presentation remain unclear.
Luc Teyton
doaj   +1 more source

Structural Dynamics of the Lipid Antigen-Binding Site of CD1d Protein

Biomolecules, 2020
CD1 molecules present lipid antigens to T-cells in early stages of immune responses. Whereas CD1‒lipid‒T-cell receptors interactions are reasonably understood, molecular details on initial trafficking and loading of lipids onto CD1 proteins are less ...
Bruno Cuevas-Zuviría, Marina Mínguez-Toral, Araceli Díaz-Perales, María Garrido-Arandia, Luis F. Pacios   +4 more
doaj   +1 more source

Pharmacokinetics and Acute Safety Evaluation of Tryptanthrin, A Bioactive Constituent of Indigo naturalis, Following Intravenous Administration in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The use of Indigo naturalis in treating inflammatory diseases is clinically restricted by severe adverse events, including pulmonary arterial hypertension and hepatotoxicity. Tryptanthrin, a major indoloquinazoline alkaloid of Indigo naturalis, exhibits potent anti‐inflammatory activity; however, its specific safety profile relative to the ...
Hyung Jin Kim, Gabsik Yang, Jun Ho Lee
wiley   +1 more source

Molecular characterisation of Ovine CD1 [PDF]

, 1994
The CD1 molecules are a family of ß2microglobulin- associated glycoproteins with strong structural homology, but weaker sequence homology, to the MHC class I antigens. In contrast to the classical class I antigens, CD1 molecules exhibit restricted
Ferguson, Elaine Dorothea
core  

Effect of Laser on the Bound Magnetic Polaron in a Semimagnetic Quantum Wire [PDF]

Журнал нано- та електронної фізики, 2011
In the present investigation binding energy of the laser dressed hydrogenic donor in a Semi magnetic Quantum Wire like Cd1 – xMnx2Te/Cd1 – x1Mnx1Te/Cd1 – x2Mnx2Te and spin polaronic shift has been computed for various magnetic and laser fields within the
C. Raja Mohan, K. Jayakumar
doaj  

Sex-Dependent Neurochemical Encoding of Acute Social Experience in Adult CD1 Mice. [PDF]

J Neurochem
A brief social interaction triggers plasma corticosterone and brain neurochemistry changes in both male and female mice, even when their behaviour appears similar. Males primarily activate glutamate‐ and dopamine‐related pathways linked to motivation and reward, whereas females rely more on noradrenergic and serotonin‐related systems associated with ...
Azkona G, Díez-Solinska A, Saez-Atxukarro O, Ochoteco-Perales L, Beitia-Oyarzabal G, Vegas O.   +5 more
europepmc   +2 more sources