Results 41 to 50 of about 14,385 (213)
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Acute myeloid leukemia (AML) is characterized by high genotypic and immunophenotypic heterogeneity. We collected an extensive dataset containing 5366 flow cytometry files from 885 AML patients, stained with the EuroFlow acute leukemia orientation tube (ALOT) and AML/MDS panel, acquired in a standardized way at eight centers over a period of 10
Sarah Bonte +13 more
wiley +1 more source
, 2022 Immunotherapy with T-cells expressing bispecific T-cell engagers (ENG T-cells) is a promising approach to improve the outcomes for patients with recurrent/refractory acute myeloid leukemia (AML).
Challice L. Bonifant (12516700) +7 more
core +1 more source
Iraqi Journal of Hematology, 2016 Background: Leukemic stem cells (LSCs) are thought to originate either from normal hematopoietic stem cells or from more differentiated progenitor cells.
Haidar H Al-Fatlawi, Raad Jaber Musa
doaj +1 more source
Diagnostic Challenges of CD4+/CD56+/CD123+ hematological neoplasms [PDF]
Anais Brasileiros de Dermatologia, 2013 In the January/February 2013 edition, Maio et al describe a patient with CD4/CD56/CD123 ascribed as blastic plasmacytoid dendritic cell neoplasia (BDCN). However, since CD4/CD56/CD123 neoplasms are highly heterogeneous, the precise diagnosis requires an extensive immunophenotypic panel. 3 Although highly suggestive, the cytochemical positivity for CD4,
Thiago, Leandro S., Sandes, Alex Freire
openaire +4 more sources
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Myelodysplastic neoplasms (MDS) are clonal hematopoietic disorders characterized by ineffective hematopoiesis, peripheral cytopenias, and a risk of progression to acute myeloid leukemia. As the disease originates in hematopoietic stem and progenitor cells (HSPCs), flow cytometry (FCM) has emerged as a key approach to interrogate the bone ...
Nicolas Chapuis +5 more
wiley +1 more source
Next‐Generation CAR‐T Cell Therapy: From Modular Design to Clinical Expansion
Exploration, EarlyView.Over the past decades, chimeric antigen receptor (CAR)‐T cell therapy has evolved from a linear engineering concept into a powerful yet constrained immunotherapy, limited by tumour microenvironment barriers, immune evasion, and manufacturing complexity.
Yuesong Bai +5 more
wiley +1 more source
Pembrolizumab‐Induced Subacute Cutaneous Lupus Erythematosus: A Case Report
JEADV Clinical Practice, EarlyView.ABSTRACT Subacute cutaneous lupus erythematosus (SCLE) is an increasingly recognized cutaneous immune‐related adverse event of immune checkpoint inhibitors. We report an 83‐year‐old woman who developed pruritic annular and polycyclic plaques 10 weeks after starting pembrolizumab for oropharyngeal squamous cell carcinoma.
Sebastiano Posenato +5 more
wiley +1 more source
Polyherbal EMSA ERITIN Promotes Erythroid Lineages and Lymphocyte Migration in Irradiated Mice
Open Life Sciences, 2016 Radiotherapy is commonly used to kill malignant cells, but it can significantly deplete hematopoietic and splenic erythroblasts. Radioprotective agents are therefore very important in clinical radiotherapy.
Ibrahim Mansur +2 more
doaj +1 more source
Optimising the Diagnosis of Sesame Seed Allergy With the Basophil Activation Test
Allergy, EarlyView.The basophil activation test (using the activation marker CD203c) was the only test able to both exclude and confirm sesame seed allergy with precision. A negative skin prick test to sesame extract or tahini and undetectable IgE to Ses i 1 could not rule out sesame seed allergy.
Ru‐Xin Foong +16 more
wiley +1 more source
Interleukin-3 receptor alpha chain (CD123) is widely expressed in hematologic malignancies
Haematologica, 2001 BACKGROUND AND OBJECTIVES: The hematopoietic system is controlled by growth factors (cytokines) which can influence cell survival, proliferation, differentiation and functional activation. The study of cytokine receptor expression by flow cytometry could
L Munoz +7 more
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