Results 11 to 20 of about 4,963 (151)

The diagnostic power of CD117, CD13, CD56, CD64, and MPO in rapid screening acute promyelocytic leukemia

open access: yesBMC Research Notes, 2020
Objective The same immuno-phenotype between HLA-DR-negative acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL) causes APL rapid screening to become difficult.
Vinh Thanh Tran   +11 more
doaj   +1 more source

CD13 Regulates Dendritic Cell Cross-Presentation and T Cell Responses by Inhibiting Receptor-Mediated Antigen Uptake [PDF]

open access: yesThe Journal of Immunology, 2012
Abstract Dendritic cell (DC) Ag cross-presentation is generally associated with immune responses to tumors and viral Ags, and enhancement of this process is a focus of tumor vaccine design. In this study, we found that the myeloid cell surface peptidase CD13 is highly and specifically expressed on the subset of DCs responsible for cross ...
Mallika, Ghosh   +4 more
openaire   +2 more sources

Prognostic value of myeloid antigens expression in childhood acute lymphoblastic leukemia

open access: yesIraqi Journal of Hematology, 2017
Background: Leukemic blasts in acute lymphoblastic leukemia (ALL) may have immunological features of both lymphoid and myeloid lineages known as aberrant myeloid antigens expression in ALL, which are explained as abnormal genetic program of leukemic ...
Aula Mahmood Ibrahim, Bassam M Hameed
doaj   +1 more source

CD13 (aminopeptidase N) can associate with tumor‐associated antigen L6 and enhance the motility of human lung cancer cells [PDF]

open access: yesInternational Journal of Cancer, 2005
AbstractCancer metastasis is a multiple‐step process that involves the regulated interaction of diverse cellular proteins. We recently reported that the expression of tumor‐associated antigen L6 (TAL6) promoted the invasiveness of lung cancer cells and was inversely correlated with disease‐free survival of squamous lung carcinoma patients.
Yu-Wen, Chang   +9 more
openaire   +2 more sources

Two methods for the quantitative analysis of surface antigen expression in acute myeloid leukemia (AML).

open access: yesFolia Histochemica et Cytobiologica, 2004
The expression of lineage molecules (CD13 and CD33), c-Kit receptor (CD117), CD34, HLA-DR and adhesion molecule CD49d was assessed in acute myeloid leukemia (AML) blast cells from 32 cases, using direct and indirect quantitative cytometric analysis. High
Jolanta Woźniak
doaj   +1 more source

Characteristics of myeloid differentiation and maturation pathway derived from human hematopoietic stem cells exposed to different linear energy transfer radiation types. [PDF]

open access: yesPLoS ONE, 2013
Exposure of hematopoietic stem/progenitor cells (HSPCs) to ionizing radiation causes a marked suppression of mature functional blood cell production in a linear energy transfer (LET)- and/or dose-dependent manner.
Satoru Monzen   +3 more
doaj   +1 more source

MULTIPARAMETRIC FLOW CYTOMETRY REFINES RISK STRATIFICATION IN NEWLY DIAGNOSED MULTIPLE MYELOMA PATIENTS

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2023
Multiple myeloma (MM) is a heterogeneous malignancy characterized by the proliferation of abnormal plasma cells in the bone marrow. Multiparametric flow cytometry (MFC) plays a role in the work-up of the disease in view of the aberrant expression of ...
Francesca Fazio   +10 more
doaj   +1 more source

Identification of APN/CD13 as the target antigen of FU3, a human monoclonal antibody that recognizes malignant fibrous histiocytoma

open access: yesInternational Journal of Oncology, 2013
Malignant fibrous histiocytoma (MFH), a high-grade, undifferentiated sarcoma, is highly aggressive, resistant to radiochemotherapy and associated with poor prognosis. There are no specific immunohistochemical markers for its diagnosis. The MFH cell line SFT7913 served as and immunogen for the generation of the FU3 monoclonal antibody in our laboratory.
Mikiko, Aoki   +4 more
openaire   +3 more sources

The immunoregulatory abilities of polymorphonuclear neutrophils in the course of multiple sclerosis

open access: yesMediators of Inflammation, 1998
The polymorphonuclear neutrophils (PMN) possess sufficient potential to affect both immune response and inflammation, however it has not been yet described in the course of multiple sclerosis (MS).
J. Ziaber   +5 more
doaj   +1 more source

Diagnostic Utility of Immunophenotyping by Flow Cytometry for Diagnosis and Classification of Acute Leukemias in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

open access: yesIndonesian Journal of Cancer, 2021
Background: Immunophenotypic characterization of acute leukemia is an important clinical application of flow cytometry and has become a powerful tool contributing to proper diagnosis and classification.
Metasebia Tegegen   +8 more
doaj   +1 more source

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