Prognostic value of myeloid antigens expression in childhood acute lymphoblastic leukemia
Background: Leukemic blasts in acute lymphoblastic leukemia (ALL) may have immunological features of both lymphoid and myeloid lineages known as aberrant myeloid antigens expression in ALL, which are explained as abnormal genetic program of leukemic ...
Aula Mahmood Ibrahim, Bassam M Hameed
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Two methods for the quantitative analysis of surface antigen expression in acute myeloid leukemia (AML). [PDF]
The expression of lineage molecules (CD13 and CD33), c-Kit receptor (CD117), CD34, HLA-DR and adhesion molecule CD49d was assessed in acute myeloid leukemia (AML) blast cells from 32 cases, using direct and indirect quantitative cytometric analysis. High
Jolanta Woźniak
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Allogeneic Hematopoietic Stem Cell Transplantation Achieves Durable Remission in Blast-Phase Chronic Myeloid Leukemia Presenting as Early T-Cell Precursor Acute Lymphoblastic Leukemia. [PDF]
ABSTRACT Introduction The presentation of chronic myeloid leukemia (CML) in the blast phase as early T‐cell precursor acute lymphoblastic leukemia (ETP‐ALL) is very rare. As previously reported, in contrast to B‐ALL, the prognosis is poor. Case Presentation We encountered a patient with blast phase CML presenting as ETP‐ALL.
Tsushima T +10 more
europepmc +2 more sources
Sequential Philadelphia-Positive Pre-B Acute Lymphoblastic Leukemia and Chronic Myeloid Leukemia With Distinct BCR::ABL1 Fusion Transcripts. [PDF]
ABSTRACT Background The sequential emergence of chronic myeloid leukemia (CML) following Philadelphia‐positive acute lymphoblastic leukemia (ALL) is exceedingly rare, and its biological basis remains uncertain. Case We report a 15‐year‐old boy initially diagnosed at age 4 with Philadelphia‐positive pre‐B ALL expressing p190 BCR::ABL1.
Latifi A, Yousefian S.
europepmc +2 more sources
A Novel <i>PICALM::AFF3</i> Fusion t(2;11) (q11.2;q21) in a Case of Myelodysplastic Neoplasm, Post Cytotoxic Therapy. [PDF]
eJHaem, Volume 7, Issue 5, October 2026.
Don MD +6 more
europepmc +2 more sources
Flow Cytometry-Guided Diagnosis of Cortical T-Lymphoblastic Lymphoma Presenting With a Massive Mediastinal Mass and Borderline Bone Marrow Involvement. [PDF]
ABSTRACT Background T‐cell lymphoblastic lymphoma (T‐LBL) and T‐cell acute lymphoblastic leukemia (T‐ALL) are considered a single biological entity, distinguished primarily by the extent of bone marrow infiltration. This distinction becomes diagnostically challenging in patients with borderline marrow blast counts and predominantly extramedullary ...
Glait-Santar C +3 more
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Objective The same immuno-phenotype between HLA-DR-negative acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL) causes APL rapid screening to become difficult.
Vinh Thanh Tran +11 more
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Evaluation of aberrant expression of CD markers in acute leukemia cells
Background and objective: Worldwide immunophenotyping by flow cytometry (FCM) in acute leukemia (AL) is the golden step in the diagnosis. It’s very common for acute leukemias to aberrantly express antigens or cluster of differentiation (CD) markers which
Lava kareem Shwani +2 more
doaj +1 more source
The Role of the Ectopeptidase APN/CD13 in Cancer [PDF]
APN/CD13 is expressed in a variety of cells/tissues and is therefore associated with diverse physiological functions, including proliferation, differentiation, migration, angiogenesis, invasion, metastasis, vasoconstriction, and the regulation of normal ...
Wolke, Carmen +7 more
core +1 more source
CD13 Regulates Dendritic Cell Cross-Presentation and T Cell Responses by Inhibiting Receptor-Mediated Antigen Uptake [PDF]
Abstract Dendritic cell (DC) Ag cross-presentation is generally associated with immune responses to tumors and viral Ags, and enhancement of this process is a focus of tumor vaccine design. In this study, we found that the myeloid cell surface peptidase CD13 is highly and specifically expressed on the subset of DCs responsible for cross ...
Mallika, Ghosh +4 more
openaire +2 more sources

