Results 11 to 20 of about 4,963 (151)
Objective The same immuno-phenotype between HLA-DR-negative acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL) causes APL rapid screening to become difficult.
Vinh Thanh Tran +11 more
doaj +1 more source
CD13 Regulates Dendritic Cell Cross-Presentation and T Cell Responses by Inhibiting Receptor-Mediated Antigen Uptake [PDF]
Abstract Dendritic cell (DC) Ag cross-presentation is generally associated with immune responses to tumors and viral Ags, and enhancement of this process is a focus of tumor vaccine design. In this study, we found that the myeloid cell surface peptidase CD13 is highly and specifically expressed on the subset of DCs responsible for cross ...
Mallika, Ghosh +4 more
openaire +2 more sources
Prognostic value of myeloid antigens expression in childhood acute lymphoblastic leukemia
Background: Leukemic blasts in acute lymphoblastic leukemia (ALL) may have immunological features of both lymphoid and myeloid lineages known as aberrant myeloid antigens expression in ALL, which are explained as abnormal genetic program of leukemic ...
Aula Mahmood Ibrahim, Bassam M Hameed
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CD13 (aminopeptidase N) can associate with tumor‐associated antigen L6 and enhance the motility of human lung cancer cells [PDF]
AbstractCancer metastasis is a multiple‐step process that involves the regulated interaction of diverse cellular proteins. We recently reported that the expression of tumor‐associated antigen L6 (TAL6) promoted the invasiveness of lung cancer cells and was inversely correlated with disease‐free survival of squamous lung carcinoma patients.
Yu-Wen, Chang +9 more
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The expression of lineage molecules (CD13 and CD33), c-Kit receptor (CD117), CD34, HLA-DR and adhesion molecule CD49d was assessed in acute myeloid leukemia (AML) blast cells from 32 cases, using direct and indirect quantitative cytometric analysis. High
Jolanta Woźniak
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Characteristics of myeloid differentiation and maturation pathway derived from human hematopoietic stem cells exposed to different linear energy transfer radiation types. [PDF]
Exposure of hematopoietic stem/progenitor cells (HSPCs) to ionizing radiation causes a marked suppression of mature functional blood cell production in a linear energy transfer (LET)- and/or dose-dependent manner.
Satoru Monzen +3 more
doaj +1 more source
Multiple myeloma (MM) is a heterogeneous malignancy characterized by the proliferation of abnormal plasma cells in the bone marrow. Multiparametric flow cytometry (MFC) plays a role in the work-up of the disease in view of the aberrant expression of ...
Francesca Fazio +10 more
doaj +1 more source
Malignant fibrous histiocytoma (MFH), a high-grade, undifferentiated sarcoma, is highly aggressive, resistant to radiochemotherapy and associated with poor prognosis. There are no specific immunohistochemical markers for its diagnosis. The MFH cell line SFT7913 served as and immunogen for the generation of the FU3 monoclonal antibody in our laboratory.
Mikiko, Aoki +4 more
openaire +3 more sources
The immunoregulatory abilities of polymorphonuclear neutrophils in the course of multiple sclerosis
The polymorphonuclear neutrophils (PMN) possess sufficient potential to affect both immune response and inflammation, however it has not been yet described in the course of multiple sclerosis (MS).
J. Ziaber +5 more
doaj +1 more source
Background: Immunophenotypic characterization of acute leukemia is an important clinical application of flow cytometry and has become a powerful tool contributing to proper diagnosis and classification.
Metasebia Tegegen +8 more
doaj +1 more source

