Results 41 to 50 of about 188,070 (188)

Clinical applications of CD34+ progenitor cell immunophenotyping in myelodysplastic neoplasms—The CytHem SMD French network experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Myelodysplastic neoplasms (MDS) are clonal hematopoietic disorders characterized by ineffective hematopoiesis, peripheral cytopenias, and a risk of progression to acute myeloid leukemia. As the disease originates in hematopoietic stem and progenitor cells (HSPCs), flow cytometry (FCM) has emerged as a key approach to interrogate the bone ...
Nicolas Chapuis, Anne‐Catherine Lhoumeau, Stéphanie Mathis, Michel Ticchioni, Valérie Bardet, the French Working Group CytHem‐SMD   +5 more
wiley   +1 more source

Herstellung und Charakterisierung von CD13-spezifischen Antikörperderivaten für die diagnostische und therapeutische Anwendung bei hämatologischen und soliden Krebserkrankungen

, 2022
Die derzeitige Krebsbehandlung geht trotz stetigem Fortschritt noch immer mit geringen Heilungschancen und gravierenden Nebenwirkungen einher. Einerseits fehlt den Standardtherapien die Selektivität, andererseits führen Krebsstammzellen (""cancer stem ...
Grieger, E.
core   +1 more source

CD105+CD90+CD13+ identifies a clonogenic subset of adventitial lung fibroblasts

, 2021
Mesenchymal cells are important components of specified niches in the lung, and can mediate a wide range of processes including tissue regeneration and repair.
Åhrman, Emma, Michaliková, Barbora, Dellgren, Göran, Scheding, Stefan, Löfdahl, Anna, Rolandsson Enes, Sara, Kadefors, Måns, Westergren-Thorsson, Gunilla, Scheding, Stefan,, Åhrman, Emma,, Löfdahl, Anna,, Michaliková, Barbora,, Kadefors, Måns,, Dellgren, Göran,, Rolandsson Enes, Sara,, Westergren-Thorsson, Gunilla,, Lund University., Gunilla Westergren-Thorsson, Sara Rolandsson Enes, Emma Åhrman, Anna Löfdahl, Barbora Michaliková, Göran Dellgren, Stefan Scheding, Måns Kadefors   +24 more
core   +1 more source

Immunophenotypic Characterization of Human Bone Marrow Mast Cells. A Flow Cytometric Study of Normal and Pathological Bone Marrow Samples

Analytical Cellular Pathology, 1998
The goal of the present paper was to define the immunophenotype of bone marrow mast cells (BMMC) from healthy controls and patients with hematologic malignancies (HM) based on the use of multiple stainings with monoclonal antibodies analyzed by flow ...
Luis Escribano, Alberto Orfao, Jesús Villarrubia, Beatriz Díaz-Agustín, Carlos Cerveró, Agustín Rios, José L. Velasco, Juana Ciudad, José L. Navarro, Jesús F. San Miguel   +9 more
doaj   +1 more source

Pleural effusion as the initial extramedullary manifestation of Acute Myeloid Leukemia [v1; ref status: indexed, http://f1000r.es/PEKat0]

F1000Research, 2012
Leukemias rarely debut by pleural involvement as the first manifestation of the hematologic malignancy. This complication is most commonly seen in solid tumors such as carcinomas of the breast, lung, gastrointestinal tract and lymphomas.
José Nieves-Nieves, Luis Hernandez-Vazquez, Dev Boodoosingh, Ricardo Fernández-Gonzalez, Rosángela Fernández-Medero, José Adorno-Fontánez, Edgardo Adorno-Fontánez, José Lozada-Costas   +7 more
doaj   +1 more source

Bone marrow-derived CD13+ cells sustain tumor progression: A potential non-malignant target for anticancer therapy [PDF]

, 2015
Non-malignant cells found within neoplastic lesions express alanyl (membrane) aminopeptidase (ANPEP, best known as CD13), and CD13-null mice exhibit limited tumor growth and angiogenesis. We have recently demonstrated that a subset of bone marrow-derived
Dondossola, Eleonora, Arap, Wadih, Corti, Angelo, Pasqualini, Renata, Sidman, Richard   +4 more
core   +1 more source

ICSH Guidance on Bone Marrow Examination and Reporting

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber, Alexandar Tzankov, Olga Pozdnyakova, Hiromichi Matsushita, Gina Zini, Leonie Saft, on behalf of the International Council for Standardization in Haematology   +6 more
wiley   +1 more source

Characterization of CD34+, CD13+, CD33- cells, a rare subset of immature human hematopoietic cells

Haematologica, 2002
BACKGROUND AND OBJECTIVES: Hematopoietic progenitor cells that express CD34 are heterogeneous in their lineage affiliation and degree of maturation. Expression of CD13 and CD33 antigens indicates myeloid lineage association, but the precise sequence of ...
G Gaipa, E Coustan-Smith, E Todisco, O Maglia, A Biondi, D Campana   +5 more
doaj  

Stromal mesenchyme cell genes of the human prostate and bladder

BMC Urology, 2005
Background Stromal mesenchyme cells play an important role in epithelial differentiation and likely in cancer as well. Induction of epithelial differentiation is organ-specific, and the genes responsible could be identified through a comparative genomic ...
Pascal Laura E, Goodlett David R, Goo Young Ah, Worthington Kelsey D, Vessella Robert L, True Lawrence D, Liu Alvin Y   +6 more
doaj   +1 more source

Distinct Epitopes on CD13 Mediate Opposite Consequences for Cell Adhesion

, 2018
CD13 is a membrane glycoprotein with aminopeptidase activity, expressed on several cell types, including myeloid cells (dendritic cells, monocytes, macrophages, neutrophils, etc.).
Enrique Ortega, Ileana Licona-Limón, Claudia A. Garay-Canales   +2 more
core   +1 more source