Results 51 to 60 of about 188,530 (334)

Detection of CD33 expression on monocyte surface is influenced by phagocytosis and temperature [PDF]

, 2019
CD33 is a myeloid-associated marker and belongs to the sialic acid-binding immunoglobulin (Ig)-like lectin (Siglec) family. Such types of receptors are highly expressed in acute myeloid leukemia, which could be used in its treatment.
Baisaeng, Nuttakorn, Boonla, Chanchai, Bäumler, Hans, Georgieva, Radostina, Kaewprayoon, Waraporn, Kloypan, Chiraphat, Smuda, Kathrin, Suwannasom, Nittiya   +7 more
core   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Comparative analysis of hepatic CD14 expression between two different endotoxin shock model mice: relation between hepatic injury and CD14 expression. [PDF]

PLoS ONE, 2013
CD14 is a glycoprotein that recognizes gram-negative bacterial lipopolysaccharide (LPS) and exists in both membrane-bound and soluble forms. Infectious and/or inflammatory diseases induce CD14 expression, which may be involved in the pathology of ...
Hiroyasu Hozumi, Rui Tada, Taisuke Murakami, Yoshiyuki Adachi, Naohito Ohno   +4 more
doaj   +1 more source

The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA [PDF]

, 2016
Alterations in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells.
Bozzoni, Irene, Fatica, Alessandro, Fazi, Francesco, Iosue', Ilaria, Larivera, Simone, Legnini, Ivano, Mangiavacchi, Arianna, Masciarelli, Silvia, Sorci, Melissa   +8 more
core   +2 more sources

Soluble CD14 and fracture risk [PDF]

Osteoporosis International, 2015
Soluble CD14 (sCD14) is an inflammatory marker associated with osteoclasts. Using Cox proportional hazards models, we found a positive association between plasma levels of sCD14 and risk of incident fracture among participants in the Cardiovascular Health Study.
Bethel, M, Bůžková, P, Fink, HA, Robbins, JA, Cauley, JA, Lee, J, Barzilay, JI, Jalal, DI, Carbone, LD   +8 more
openaire   +4 more sources

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

CD14 genotype and functional dichotomy of CD14+ and CD14- cells are associated with activated immune response and development of Chagas dilated cardiomyopathy [PDF]

Memorias do Instituto Oswaldo Cruz
We aimed to investigate the association of CD14 -260C/T (rs2569190) polymorphism and Chagas cardiomyopathy and the functional characteristics of CD14+ and CD14- monocytes upon infection with Trypanosoma cruzi.
Germano Carneiro Costa, Manoel Otávio da Costa Rocha, Paulo Eduardo Alencar de Souza, Diego Felipe SA Melo, Paula Rocha Moreira, Kenneth John Gollob, Maria do Carmo Pereira Nunes, Walderez Ornelas Dutra   +7 more
doaj   +2 more sources

Plasma Soluble CD14 Subtype Levels Are Associated With Clinical Outcomes in Critically Ill Subjects With Coronavirus Disease 2019

Critical Care Explorations, 2021
IMPORTANCE:. In bacterial sepsis, CD14 and its N-terminal fragment (soluble CD14 subtype, “Presepsin”) have been characterized as markers of innate immune responses and emerging evidence has linked both to coronavirus disease 2019 pathophysiology ...
F. Linzee Mabrey, MD, Eric D. Morrell, MD, Pavan K. Bhatraju, MD, MSc, Neha A. Sathe, MD, Sana S. Sakr, PhD, Sharon K. Sahi, BS, T. Eoin West, MD, MPH, Carmen Mikacenic, MD, Mark M. Wurfel, MD, PhD   +8 more
doaj   +1 more source

M-DC8+leukocytes - A novel human dendritic cell population [PDF]

, 1999
Dendritic cells (DC) constitute a heterogeneous leukocyte population having in common a unique capacity to induce primary T cell responses and are therefore most attractive candidates for immunomodulatory strategies.
Federle, Christine, Mayer, Elfriede, Poppe, Claudia, Rieber, Ernst Peter, Riethmüller, Gert, Schäkel, Knut   +5 more
core   +2 more sources

Bioinspired Stabilization of Fluorescent Au@SiO2 Tracers for Multimodal Biological Imaging

Advanced Functional Materials, EarlyView.
This study demonstrates a bioinspired stabilization strategy for fluorescent gold‐silica nanoparticles. Inspired by natural biosilica maturation, high‐temperature calcination transforms the silica shells, preventing dissolution in cell culture media and intracellular environments.
Wang Sik Lee, Henry Lee, Patricia Taladriz‐Blanco, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Alke Petri‐Fink   +5 more
wiley   +1 more source