Results 51 to 60 of about 98,093 (297)

Endometrial CD16(+) and CD16(-) NK cell count in fertility and unexplained infertility [PDF]

, 2013
Problem: Peripheral counts of CD16+ NK cells have been well characterized in reproductive failure. However, not enough case-control clinical studies have been conducted to establish normal or abnormal CD16+/- values in the endometrium.
Incera, Maria Eugenia, Ferrer, Maria Constanza, Gutierrez, Gabriela Lidia, Junovich, Gisela Yael, Pasqualini, Rodolfo Agustin, Azpiroz, Maria Agustina   +5 more
core   +1 more source

A Novel Mutation in the FcγRIIIA Gene (CD16) Results in Active Natural Killer Cells Lacking CD16

Autoimmunity, 1999
We report a novel mutation in FcgammaRIIIA (the transmembrane-form CD16) on natural killer (NK) cells in a patient with polyneuropathy. She had no history of recurrent infections. Her NK cells expressed no detectable CD16; however, her NK cytotoxic activity was normal, suggesting that CD16 expression and cytotoxic activity are independent of one ...
Tohru Takeuchi, Toshimasa Nakagawa, Jose T. Ramos-Amador, Toshiyuki Ikemoto, Masako Sasaki, Shigeki Makino, Akira Shimizu, Nakaaki Ohsawa   +7 more
openaire   +2 more sources

A Novel, Five-Marker Alternative to CD16–CD14 Gating to Identify the Three Human Monocyte Subsets

Frontiers in Immunology, 2019
Human primary monocytes are heterogeneous in terms of phenotype and function, but are sub-divided only based on CD16 and CD14 expression. CD16 expression distinguishes a subset of monocytes with highly pro-inflammatory properties from non-CD16 expressing
Siew-Min Ong, Karen Teng, Evan Newell, Hao Chen, Jinmiao Chen, Thomas Loy, Thomas Loy, Tsin-Wen Yeo, Tsin-Wen Yeo, Katja Fink, Katja Fink, Siew-Cheng Wong, Siew-Cheng Wong   +12 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Photoacoustic Nanotagging for In Vivo Tracking and Optimization of Macrophage Immunotherapy in Solid Tumors

Advanced Materials, EarlyView.
Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song, Melissa Cadena, Myeongsoo Kim, Euisuk Chung, Jeungyoon Lee, Zlata Brushevich, Seonghun Shin, Paul S. Pelkowski, Stanislav Y. Emelianov   +8 more
wiley   +1 more source

Phenotype remodeling in neutrophilic granulocyte subsets CD64^-CD32⁺CD16⁺CD11B⁺NG, CD64⁺CD32⁺CD16⁺CD11B⁺NG in de novo experimental model of viral-bacterial infection in vitro

Инфекция и иммунитет, 2021
A search for new targeted therapeutic strategies based on examining immunopathogenetic mechanisms for emerging co-infections is relevant and may further contribute not only to optimizing choice of immunotropic drugs, but also to achieving positive ...
I. V. Nesterova, G. A. Chudilova, T. V. Rusinova, V. N. Pavlenko, Ya. A. Yutskevich, N. K. Barova, V. A. Tarakanov   +6 more
doaj   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

CD14+CD16+ monocyte subpopulation in Kawasaki disease [PDF]

Clinical and Experimental Immunology, 2000
SUMMARY Kawasaki disease (KD) is an acute febrile illness caused by vasculitis, occurring in early childhood. We have demonstrated that the activation of monocytes/macrophages plays a central role during acute KD. Recently, it has been reported that the CD14+CD16+ monocyte subpopulation plays a more important role in inflammation.
K, Katayama, T, Matsubara, M, Fujiwara, M, Koga, S, Furukawa   +4 more
openaire   +2 more sources

Expression features of CD16 and NKG2D receptors by NK cells, NKT cells and T lymphocytes of peripheral blood associated with female infertility

Медицинская иммунология
The increasing incidence of infertility determines relevance of studying various cellular factors, including immune cells, in pathogenesis of this disorder.
V. A. Mikhailova, A. A. Davydova, V. A. Zagaynova, O. B. Marko, E. R. Mkrtchyan, A. S. Zhguleva, O. A. Bakulina, S. A. Selkov, O. N. Bespalova, D. I. Sokolov   +9 more
doaj   +1 more source

Tumor Infiltration by OX40+ Cells Enhances the Prognostic Significance of CD16+ Cell Infiltration in Colorectal Cancer

Cancer Control, 2020
Objectives: Analysis of tumor immune infiltration has been suggested to outperform tumor, node, metastasis staging in predicting clinical course of colorectal cancer (CRC).
Fabian Haak, Isabelle Obrecht, Nadia Tosti, Benjamin Weixler MD, Robert Mechera MD, Silvio Däster MD, Marco von Strauss MD, Tarik Delko MD, Giulio C. Spagnoli, Luigi Terracciano MD, Giuseppe Sconocchia, Markus von Flüe MD, Marko Kraljević MD, Raoul A. Droeser MD   +13 more
doaj   +1 more source