Results 61 to 70 of about 98,093 (297)

Variation in dietary salt intake induces coordinated dynamics of monocyte subsets and monocyte-platelet aggregates in humans: implications in end organ inflammation. [PDF]

PLoS ONE, 2013
BACKGROUND: Monocyte activation and tissue infiltration are quantitatively associated with high-salt intake induced target organ inflammation. We hypothesized that high-salt challenge would induce the expansion of CD14++CD16+ monocytes, one of the three ...
Xin Zhou, Ling Zhang, Wen-Jie Ji, Fei Yuan, Zhao-Zeng Guo, Bo Pang, Tao Luo, Xing Liu, Wen-Cheng Zhang, Tie-Min Jiang, Zhuoli Zhang, Yu-Ming Li   +11 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

CD14++CD16+ monocyte linear correlation analysis.

, 2013
A, shows the correlation between CD14++CD16+ counts and CD14++CD16+ MPA counts on day 4. B and C, show the correlation of net changes (day 4 minus day 3) between CD14++CD16+ percentages/counts and 24 h urinary sodium. Mon2 indicates CD14++CD16+ monocytes;
Zhao-Zeng Guo (398951), Tie-Min Jiang (398952), Wen-Jie Ji (398950), Xing Liu (221084), Zhuoli Zhang (155370), Xin Zhou (54275), Bo Pang (164741), Yu-Ming Li (398953), Ling Zhang (18071), Tao Luo (232520), Wen-Cheng Zhang (327773), Fei Yuan (24924)   +11 more
core   +1 more source

IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study [PDF]

, 2011
In an ongoing clinical phase I/II study, 16 pediatric patients suffering from high risk leukemia/tumors received highly purified donor natural killer (NK) cell immunotherapy (NK-DLI) at day (+3) +40 and +100 post haploidentical stem cell transplantation.
Claudia Brehm, Bader Peter, Soerensen, Jan, Klingebiel Thomas, Seidl, Christian, Christian Seidl, Petra S. A. Becker, Bremm Melanie, Koehl Ulrike, Becker, Petra S. A., Jakob R. Passweg, Sabine Huenecke, Andrea Quaiser, Peter Bader, Koehl, Ulrike, Thomas Klingebiel, Ulrike Koehl, Jakob R Passweg, Brehm Claudia, Jan Soerensen, Hermann Kreyenberg, Schwabe Dirk, Becker Petra S. A., Brehm, Claudia, Quaiser, Andrea, Petra S A Becker, Bader, Peter, Sörensen, Jan, Mühl Heiko, Stephan Kloess, Huenecke, Sabine, Mühl, Heiko, Klingebiel, Thomas, Esser Ruth, Klöß, Stephan, Esser, Ruth, Hünecke, Sabine, Kloess, Stephan, Huenecke Sabine, Kreyenberg Hermann, Seidl Christian, Melanie Bremm, Kreyenberg, Hermann, Bremm, Melanie, Heiko Mühl, Ruth Esser, Dirk Schwabe, Soerensen Jan, Köhl, Ulrike, Quaiser Andrea, Passweg, Jakob R., Schwabe, Dirk, Kloess Stephan, Passweg Jakob R.   +53 more
core   +1 more source

OXIDANT ALTERATIONS IN CD16 EXPRESSION ARE CYTOSKELETAL INDUCED [PDF]

Shock, 2009
Oxidative stress during reperfusion of ischemia is associated with a phenotypic change in circulating monocytes from CD14++CD16- to a proinflammatory CD14+CD16+ subpopulation resulting in altered immunity and development of organ failure. However, the mechanism responsible remains unknown. We hypothesize that this phenotypic change, modeled by hydrogen
Joseph, Cuschieri, Sana, Sakr, Eileen, Bulger, Megan, Knoll, Saman, Arbabi, Ronald V, Maier   +5 more
openaire   +2 more sources

Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles. [PDF]

PLoS ONE, 2011
To explore the capacity of human CD1⁺CD16⁺⁺ and CD14⁺⁺CD16⁻ monocytes to phagocyte iron-oxide nanoparticles in vitro.Human monocytes were labeled with four different magnetic nanoparticle preparations (Ferumoxides, SHU 555C, CLIO-680, MION-48) exhibiting
Marcus Settles, Martin Etzrodt, Katja Kosanke, Matthias Schiemann, Alexander Zimmermann, Reinhard Meier, Rickmer Braren, Armin Huber, Ernst J Rummeny, Ralph Weissleder, Filip K Swirski, Moritz Wildgruber   +11 more
doaj   +1 more source

Differentiation and subpopulation composition of VEGFR2+ cells in the blood and bone marrow in ischemic cardiomyopathy

Бюллетень сибирской медицины, 2022
Aim. To identify disturbances of differentiation and subpopulation composition of VEGFR2+ cells in the blood and bone marrow associated with the features of the cytokine profile in the blood and bone marrow in patients with coronary artery disease (CAD ...
S. P. Chumakova, O. I. Urazova, V. M. Shipulin, O. A. Denisenko, T. E. Kononova, K. V. Nevskaya, S. L. Andreev   +6 more
doaj   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Adipose-derived mesenchymal stem cells modulate CD14++CD16+ expression on monocytes from sepsis patients in vitro via prostaglandin E2

Stem Cell Research & Therapy, 2017
Background Mesenchymal stem cells (MSCs) have been shown to reduce sepsis-induced inflammation and improve survival in mouse models of sepsis. CD16+ monocytes are proinflammatory and abundant in inflammatory conditions such as sepsis.
Guanguan Qiu, Guoping Zheng, Menghua Ge, Lanfang Huang, Haijiang Tong, Ping Chen, Dengming Lai, Yaoqin Hu, Baoli Cheng, Qiang Shu, Jianguo Xu   +10 more
doaj   +1 more source