Results 11 to 20 of about 57,461 (287)

CD163 and its role in inflammation

Folia Histochemica et Cytobiologica, 2011
Mononuclear phagocytes represent a heterogeneous population of cells with individual subpopulations exerting different pro- or anti-inflammatory functions.
Lech Chyczewski, Marek Bielecki, Emila Sławińska, Richard Silver, Krzysztof Kowal, Otylia Kowal-Bielecka   +5 more
doaj   +5 more sources

HOXA9 and CD163 potentiate pancreatic ductal adenocarcinoma progression

Diagnostic Pathology
Background The role of HOXA9 requires investigations in pancreatic ductal adenocarcinoma (PDAC) as HOXA9 inhibitors are being developed. HOXA9 might attract CD163 expressed tumor associated macrophages (TAM) and could affect PDAC prognosis.
Aiat Shaban Hemida, Mohamed Mohamady Ahmed, Mona Saeed Tantawy   +2 more
doaj   +3 more sources

Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of ‘soluble CD163’ in plasma [PDF]

Scientific Reports, 2017
AbstractCD163 is the macrophage receptor for uptake of hemoglobin-haptoglobin complexes. The human receptor can be shed from the macrophage surface owing to a cleavage site for the inflammation-inducible TACE/ADAM17 enzyme. Accordingly, plasma ‘soluble CD163’ (sCD163) has become a biomarker for macrophage activity and inflammation.
Etzerodt, Anders, Berg, Ronan M. G., Plovsing, Ronni R., Andersen, Morten N., Bebien, Magali, Habbeddine, Mohamed, Lawrence, Toby, Moller, Holger J., Moestrup, Soren K.   +8 more
openaire   +3 more sources

Peripheral blood CD163(+) monocytes and soluble CD163 in dry and neovascular age‐related macular degeneration [PDF]

The FASEB Journal, 2020
Abstract Macrophages are the main infiltrating immune cells in choroidal neovascularization (CNV), a hallmark of the human wet, or neovascular age‐related macular degeneration (AMD). Due to their plasticity and ability to adapt to the local microenvironment in a tissue‐dependent manner, macrophages display polar ...
Narsis, Daftarian, Souska, Zandi, Golbarg, Piryaie, Mahin, Nikougoftar Zarif, Ehsan, Ranaei Pirmardan, Muneo, Yamaguchi, Qurban, Behzadian Nejad, Hossein, Hasanpour, Shahram, Samiei, Isabel B, Pfister, Zahra-Soheila, Soheili, Shintaro, Nakao, Aliaa, Barakat, Justus G, Garweg, Hamid, Ahmadieh, Ali, Hafezi-Moghadam   +15 more
openaire   +2 more sources

Human monocyte CD163 expression inversely correlates with soluble CD163 plasma levels [PDF]

Cytometry Part B: Clinical Cytometry, 2004
AbstractBackgroundCD163 is a monocyte/macrophage‐restricted receptor involved in the clearance of hemoglobin–haptoglobin complexes and regulation of inflammatory processes. CD163 is shed from the cell surface and exists as a soluble form in plasma (sCD163).
Bruce H, Davis, Petar V, Zarev
openaire   +2 more sources

CD163 expression in leukemia cutis [PDF]

Journal of Cutaneous Pathology, 2010
Background: Proper diagnosis of myeloid leukemia cutis (LC) is of great clinical importance but can be difficult because no single immunohistochemical marker is adequately sensitive or specific for definitive diagnosis. Thus, a broader panel of markers is often desirable.
Harms, Paul W., Bandarchi, Bizhan, Ma, Linglei   +2 more
openaire   +3 more sources

Genetic markers associated with field PRRSV-induced abortion rates [PDF]

, 2019
In gilts and sows, the more severe clinical manifestation of PRRSV occurs in late gestation and can result in up to 40% of abortion incidence. Despite the known genetic component in the resilience to PRRSV, there is scarce information regarding the ...
Blasco-Felip, María, Estany Illa, Joan, Fernández, Carlos, Fraile Sauce, Lorenzo José, Pena i Subirà, Ramona Natacha   +4 more
core   +2 more sources

Regulation of CD163 mRNA and soluble CD163 protein in human adipose tissue in vitro [PDF]

Journal of Molecular Endocrinology, 2014
CD163-positive macrophages are highly expressed in the human adipose tissue (AT) particularly from obese individuals. However, little is known about the regulation of CD163 mRNA and the protein level of sCD163 in human AT. We aimed to examine the regulation of CD163 and sCD163 in AT. Human s.c.
Fjeldborg, Karen, Møller, Holger J, Richelsen, Bjørn, Pedersen, Steen B   +3 more
openaire   +2 more sources

Bisdemethoxycurcumin and Its Cyclized Pyrazole Analogue Differentially Disrupt Lipopolysaccharide Signalling in Human Monocyte-Derived Macrophages [PDF]

, 2018
open11noSeveral studies suggest that curcumin and related compounds possess antioxidant and anti-inflammatory properties including modulation of lipopolysaccharide- (LPS-) mediated signalling in macrophage cell models. We here investigated the effects of

core   +1 more source

CD163⁺ Foamy Macrophages Are Associated with the Morphogenesis of Oral Verruciform Xanthoma through Angiogenesis by VEGF Expression: An Immunohistochemical Study

Dentistry Journal, 2020
Oral verruciform xanthoma (OVX) is an uncommon benign lesion that is characterized histologically by the accumulation of several foamy macrophages in the lamina propria papillae.
Manabu Shigeoka, Yu-ichiro Koma, Takayuki Kodama, Mari Nishio, Masaya Akashi, Hiroshi Yokozaki   +5 more
doaj   +1 more source