Results 41 to 50 of about 57,461 (287)

Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients

Cells, 2021
Pulmonary iron levels are increased in chronic obstructive pulmonary disease (COPD) patients. Iron causes oxidative stress and is a nutrient for pathogenic bacteria. Iron may therefore play an important role in the pathophysiology of COPD.
Andrew Higham, James M. Baker, Natalie Jackson, Rajesh Shah, Simon Lea, Dave Singh   +5 more
doaj   +1 more source

In vitro differentiation of porcine blood CD163− and CD163+ monocytes into functional dendritic cells

Immunobiology, 2004
Swine monocytes constitute a heterogeneous cell population containing subsets with distinct functional capacities or representing different maturational stages. Based on the expression of CD163, we have recently identified two monocyte subpopulations.
Sonia, Chamorro, Concepción, Revilla, Nuria, Gómez, Belén, Alvarez, Fernando, Alonso, Angel, Ezquerra, Javier, Domínguez   +6 more
openaire   +3 more sources

Increased systemic inflammation is associated with cardiac and vascular dysfunction over the first 12 weeks of antiretroviral therapy among undernourished, HIV-infected adults in Southern Africa. [PDF]

, 2015
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.INTRODUCTION ...
Bala, J, Bestawros, M, Blevins, M, Canipe, A, Chidumayo, T, Filteau, S, Heimburger, DC, Kelly, P, Koethe, JR, Shepherd, BE   +9 more
core   +1 more source

Tissue Levels of CD80, CD163 and CD206 and Their Ratios in Periodontal and Peri-Implant Health and Disease

Current Issues in Molecular Biology, 2022
This study aimed to compare tissue levels of CD80 (pro-inflammatory macrophage-related surface marker), CD163, and CD206 (anti-inflammatory macrophage-related surface markers), and their ratios in periodontal and peri-implant health and disease ...
Mustafa Yilmaz, Esra Demir, Yigit Firatli, Erhan Firatli, Ulvi Kahraman Gürsoy   +4 more
doaj   +1 more source

Soluble CD163 Levels and CD163+CD14+ Monocyte/Macrophage Counts in Patients with Asthma.

Iranian journal of immunology : IJI, 2018
CD163-expressing macrophages are involved in the inflammatory response in asthma.To assess sputum and serum soluble CD163 (sCD163) and cytokine levels in patients with asthma. Further discussed was the difference between sCD163 and other classic inflammatory mediators.Sputum was successfully induced in asthma patients (n=85) and healthy controls (n=21).
Zhi, Yue, Gao, Peng, Li, Wei, Zhang, Jie, Gao, Fengling, Zhang, Jichun, Lin, Haitao   +6 more
openaire   +3 more sources

Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer [PDF]

, 2018
Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that frequently develop in response to therapies.
Altieri, Dario C., Bowler, Nicholas, Craig Hooper, D., Dutta, Anindita, Ertel, Adam, Fedele, Carmine, Forsberg, Flemming, Fortina, Paolo, Gabrilovich, Dmitry I., Harshyne, Larry A., Kean, Rhonda B., Kelly, William K., Kossenkov, Andrew V., Krishn, Shiv Ram, Kurtoglu, Senem, Languino, Lucia R., Liu, Qin, Lu, Huimin, Speicher, David W., Stanczak, Maria, Tang, Hsin-Yao, Wang, Kerith, Weinreb, Paul H., Yu, Lei   +23 more
core   +1 more source

Dexamethasone enhances CD163 expression in porcine IPKM immortalized macrophages [PDF]

In Vitro Cellular & Developmental Biology - Animal, 2021
AbstractIn our previous study, we established a unique porcine macrophage cell line, immortalized porcine kidney-derived macrophages (IPKM). The purpose of the present study was to further elucidate the characteristics of IPKM. CD163 is a scavenger receptor for the hemoglobin-haptoglobin complex and is used as a phenotypic marker of anti-inflammatory ...
Takenouchi, Takato, Morozumi, Takeya, Wada, Emi, Suzuki, Shunichi, Nishiyama, Yasutaka, Sukegawa, Shin, Uenishi, Hirohide   +6 more
openaire   +2 more sources

Replication characteristics of porcine reproductive and respiratory syndrome virus (PRRSV) European subtype 1 (Lelystad) and subtype 3 (Lena) strains in nasal mucosa and cells of the monocytic lineage: indications for the use of new receptors of PRRSV (Lena) [PDF]

, 2013
Recently, it has been demonstrated that subtype 3 strains of European type porcine reproductive and respiratory syndrome virus (PRRSV) are more virulent/pathogenic than subtype 1 strains. This points to differences in the pathogenesis.
Cao, Jun, Frydas, Ilias, Nauwynck, Hans, Verbeeck, Mieke   +3 more
core   +2 more sources

Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases [PDF]

International Journal of Molecular Sciences, 2020
The macrophage is a key cell in the pro- and anti-inflammatory response including that of the inflammatory microenvironment of malignant tumors. Much current drug development in chronic inflammatory diseases and cancer therefore focuses on the macrophage as a target for immunotherapy.
Skytthe, Maria K., Graversen, Jonas Heilskov, Moestrup, Søren K.   +2 more
openaire   +5 more sources

Multi-lectin Affinity Chromatography and Quantitative Proteomic Analysis Reveal Differential Glycoform Levels between Prostate Cancer and Benign Prostatic Hyperplasia Sera. [PDF]

, 2018
Currently prostate-specific antigen is used for prostate cancer (PCa) screening, however it lacks the necessary specificity for differentiating PCa from other diseases of the prostate such as benign prostatic hyperplasia (BPH), presenting a clinical need
Adusumilli, Ravali, Brooks, James D, Kullolli, Majlinda, Mallick, Parag, Pitteri, Sharon J, Tanimoto, Cheylene, Totten, Sarah M   +6 more
core   +2 more sources