Results 21 to 30 of about 15,640 (205)
Spatial patterns and prognostic relevance of CD1a+ immature and CD208+ mature dendritic cells in colorectal cancer from non-tumor adjacent mucosa to liver metastases [PDF]
Cancer Immunology, ImmunotherapyThe prognostic role of dendritic cells (DCs) in colorectal cancer (CRC) and paired liver metastases (LM) remains unclear, particularly regarding the dynamics of immature CD1a+ and mature CD208+ subsets across anatomical compartments and synchronous ...
Sergii Pavlov +9 more
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Indeterminate dendritic cell tumor (IDCT) [PDF]
Vestnik Dermatologii i Venerologii, 2023 Indeterminate dendritic cell tumor (IDCT) is rare histiocytic tumor characterized by the proliferation of indeterminate dendritic cells. It is more often diagnosed in middle-aged people, in approximately equal proportions in men and women.
Evgenia V. Okladnikova +4 more
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The role of CD1a and phospholipase A2 in psoriasis [PDF]
, 2016 Psoriasis is a chronic inflammatory skin disease associated with a T helper 17 (Th17) response, yet it has proved challenging to identify relevant peptide-based T cell antigens. Langerhans cells show a differential migration phenotype in psoriatic lesions and express constitutively high levels of CD1a, which presents lipid antigens to T cells.
Cheung, Ka Lun
openaire +3 more sources
Adult-onset of Langerhans cell histiocytosis: a clinical case
Alʹmanah Kliničeskoj Mediciny, 2021 Langerhans cell histiocytosis is mainly diagnosed in children, and its manifestation in adult age is quite uncommon. Skin rashes may be non-specific and mimic a number of dermatoses.
Olga V. Chernysheva +3 more
doaj +1 more source
Langerhans Cell Expression in Oral Submucous Fibrosis: An Immunohistochemical Analysis [PDF]
Journal of Clinical and Diagnostic Research, 2015 Background: Langerhans cells (LCs), are dendritic cells of the epithelium which play a role in an array of oral lesions from gingivitis to oral cancer.
Bharghavi Narayanan, Malathi Narasimhan
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Journal for ImmunoTherapy of Cancer, 2022 Background The dismal clinical outcome of relapsed/refractory (R/R) T cell acute lymphoblastic leukemia (T-ALL) highlights the need for innovative targeted therapies.
Pablo Menendez +12 more
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Expression and significance of dendritic cell markers CD123, FXⅢA and CD1a in leprosy lesions
Pifu-xingbing zhenliaoxue zazhi, 2021 Objective: To explore the role of dendritic cells in the pathogenesis of leprosy. Method: The expression of three dendritic cell markers (CD123, FXⅢA, CD1a) in leprosy lesions was assessed by immunohistochemical staining, and their significance was ...
Wenjun ZHOU, Yan QIN
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Cerebral CD1a positive Rosai–Dorfman disease with coexistent granulomatous angiitis: A case report
Glioma, 2022 Rosai–Dorfman disease (RDD) is a nonneoplastic histiocytic proliferation. RDD is CD1a negative as opposed to Langerhans cell histiocytosis (LCH). The lesion was positive for CD1a immunohistochemistry in our RDD patient, suggesting an overlap with LCH. In
Sweety Vijay Shinde, Asha Sharad Shenoy
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The Korean Journal of Gastroenterology, 2022 Langerhans cell histiocytosis (LCH) is reported less frequently in adults than in children. The most common site of involvement in adults is the bone, accounting for 30-50% of cases. The gastrointestinal tract is very rare, accounting for approximately 2%
Seong Je Kim +8 more
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Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a [PDF]
, 2023 Expressed on epidermal Langerhans cells, CD1a presents a range of self-lipid antigens found within the skin; however, the extent to which CD1a presents microbial ligands from bacteria colonizing the skin is unclear.
Karantza, Ioanna Maria +24 more
core +1 more source