Results 31 to 40 of about 733 (164)

Development of an indirect ELISA for the identification of African swine fever virus wild-type strains and CD2v-deleted strains

Frontiers in Veterinary Science, 2022
African swine fever (ASF) is a potent infectious disease with detrimental effects on the global swine industry and no currently vaccine available. The emergence of low-virulence CD2v-deleted mutants manifested as non-hemadsorption (non-HAD) strains ...
Wenting Jiang, Wenting Jiang, Dawei Jiang, Dawei Jiang, Dawei Jiang, Lu Li, Lu Li, Bo Wan, Bo Wan, Bo Wan, Jiabin Wang, Jiabin Wang, Panpan Wang, Panpan Wang, Xuejian Shi, Xuejian Shi, Qi Zhao, Qi Zhao, Jinxing Song, Jinxing Song, Zixiang Zhu, Zixiang Zhu, Pengchao Ji, Pengchao Ji, Pengchao Ji, Gaiping Zhang, Gaiping Zhang, Gaiping Zhang, Gaiping Zhang   +28 more
doaj   +1 more source

Subtle Genetic Shifts of African Swine Fever Virus Among Vietnamese Domestic Swine Following Live-Attenuated Vaccine Commercialization. [PDF]

Transbound Emerg Dis
Since its first incursion in 2019, African swine fever (ASF) has remained a constant threat to the Vietnamese swine industry. The nationwide commercialization and implementation of live‐attenuated vaccines (LAVs), alongside depopulation‐repopulation efforts, necessitate a critical assessment of whether these strategies have driven inadvertent changes ...
Nguyen TC, Tantitaveewattana P, Pamornchainavakul N, Do DT, Kedkovid R, Thanawongnuwech R.   +5 more
europepmc   +2 more sources

Processing and Localization of the African Swine Fever Virus CD2v Transmembrane Protein [PDF]

Journal of Virology, 2011
ABSTRACTThe African swine fever virus (ASFV)-encoded CD2v transmembrane protein is required for the hemadsorption of red blood cells around infected cells and is also required for the inhibition of bystander lymphocyte proliferation in response to mitogens.
Lynnette C, Goatley, Linda K, Dixon
openaire   +2 more sources

Identification of a linear B-cell epitope on the African swine fever virus CD2v protein

International Journal of Biological Macromolecules, 2023
African swine fever virus (ASFV) poses a serious threat to domestic pigs and wild boars, which is responsible for substantial production and economic losses. A dominant ASFV specific linear B cell epitope that reacted with the convalescent serum was explored and identified with the help of immune informatics techniques. It is essential in understanding
Jinxing, Song, Mengxiang, Wang, Yongkun, Du, Bo, Wan, Angke, Zhang, Yuhang, Zhang, Guoqing, Zhuang, Pengchao, Ji, Yanan, Wu, Gaiping, Zhang   +9 more
openaire   +2 more sources

Identification of Promiscuous African Swine Fever Virus T-Cell Determinants Using a Multiple Technical Approach [PDF]

, 2021
The development of subunit vaccines against African swine fever (ASF) is mainly hindered by the lack of knowledge regarding the specific ASF virus (ASFV) antigens involved in protection.
Accensi, Francesc, Bosch-Camós, Laia, Carrascal, Montserrat, Collado, Javier, Correa-Fiz, Florencia, Domínguez, Javier, López, Elisabet, Navas, María Jesús, Nikolin, Veljko, Park, Chankyu, Pina-Pedrero, Sonia, Rodríguez, Fernando, Salas, Maria Luisa   +12 more
core   +1 more source

Cross-protection against African swine fever virus upon intranasal vaccination is associated with an adaptive-innate immune crosstalk [PDF]

, 2022
African swine fever virus (ASFV) is causing a worldwide pandemic affecting the porcine industry and leading to important global economic consequences. The virus causes a highly lethal hemorrhagic disease in wild boars and domestic pigs. Lack of effective
Accensi Alemany, Francesc, Alonso, Uxía, Argilaguet, Jordi, Bataklieva, Stanimira, Bosch Camós, Laia, Caratù, Ginevra, Chang, Chia-Yu, Dabad, Marc, Esteve-Codina, Anna, Gavrilov, Boris, Liu, Lihong, Martín-Mur, Beatriz, Muñoz, Marta, Navas, María Jesús, Pina-Pedrero, Sonia, Pleguezuelos, Patricia, Rodriguez, Fernando, Salas, María L., Vidal Barba, Enric   +18 more
core   +7 more sources

Vaccines for African swine fever: an update [PDF]

, 2023
African swine fever (ASF) is a fatal infectious disease of swine caused by the African swine fever virus (ASFV). Currently, the disease is listed as a legally notifiable disease that must be reported to the World Organization for Animal Health (WOAH ...
Haojie Zhang, Hongliang Zhang, Hu Shan, Saisai Zhao, Saisai Zhao, Xiulei Cai, Zhihua Qin   +6 more
core   +1 more source

The African Swine Fever Virus with MGF360 and MGF505 Deleted Reduces the Apoptosis of Porcine Alveolar Macrophages by Inhibiting the NF-κB Signaling Pathway and Interleukin-1β

Vaccines, 2021
African swine fever virus (ASFV) poses serious threats to the swine industry. The mortality rate of African swine fever (ASF) is 100%, and there is no effective vaccine currently available.
Qi Gao, Yunlong Yang, Weipeng Quan, Jiachen Zheng, Yizhuo Luo, Heng Wang, Xiongnan Chen, Zhao Huang, Xiaojun Chen, Runda Xu, Guihong Zhang, Lang Gong   +11 more
doaj   +1 more source

African Swine Fever Virus CD2v protein promotes β-Interferon expression and apoptosis in swine cells [PDF]

, 2020
ABSTRACTAfrican swine fever (ASF) is a disease of swine characterized by massive lymphocyte depletion in lymphatic tissues due to apoptosis of B and T cells, most likely triggered by proteins or factors secreted by infected adjacent macrophages. Here we describe a role for the ASF virus (ASFV) protein CD2v in apoptosis induction in lymphocytes. CD2v is
Sabal Chaulagain, Gustavo Delhon, Sushil Khatiwada, Daniel L. Rock   +3 more
openaire   +1 more source

In silico analysis of highly conserved cytotoxic T-cell epitopes in the structural proteins of African swine fever virus [PDF]

Veterinary World, 2021
Background and Aim: African swine fever (ASF) is a viral disease of pigs caused by ASF virus (ASFV). High mortality and the lack of available treatments have severely impacted the swine industry resulting in huge global economic losses.
Leana Rich De Mesa Herrera, Elizabeth Paulino Bisa   +1 more
doaj   +1 more source