Results 51 to 60 of about 276,103 (303)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Particular features of angiogenesis in lesions in patients suffering from basal cell epithelioma

Vestnik Dermatologii i Venerologii, 2017
Basal cell epithelioma is one of the most frequent malignant skin neoplasms. Angiogenesis plays an important part in the development of basal cell epithelioma.
A. N. Khlebnikova, N. V. Novoselova
doaj   +1 more source

CD34 and FSHR Expression to Differentiate Multiple Subtypes of Benign and Malignant Renal Neoplasms

Société Internationale d’Urologie Journal, 2022
BackgroundCurrently, no markers accurately differentiate benign from malignant renal masses. CD34 and FSHR are transmembrane proteins involved in neo-angiogenetic pathways and are differently expressed in several normal and cancerous tissues.
Giancarlo Marra, Didier Meseure, Marine Lefèvre, Andre Nicolas, Laetitia Lesage, Nicolae Ghinea, Marco Moschini, Caio Pasquali, Petr Macek, Claudia Filippini, Paolo Gontero, Rafael Sanchez-Salas, Xavier Cathelineau   +12 more
doaj   +1 more source

Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia [PDF]

, 2013
Key Points First report demonstrating in vivo elimination of multiple LIC populations from childhood ALL cases using animal models. In vivo models of leukemia are essential for drug evaluation studies.
Blair, Allison, Cox, Charlotte V, Diamanti, Paraskevi, Moppett, John P   +3 more
core   +2 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Significance of Bcl-2、CD10、CD34 and CK15 expression in differentiating basal cell carcinoma from trichoepithelioma

Pifu-xingbing zhenliaoxue zazhi, 2019
Objective: To compare expression of Bcl-2, CD10, CD34 and CK15 in basal cell carcinoma(BCC) versus trichoepithelioma(TE), and to explore the significance of their expression in diagnosis and differential diagnosis of these two disorders.
Bing-mei LIU, Rong-gui XING, Li-jie XIA, Li LI, Han-wen ZHANG, Xue CHENG   +5 more
doaj   +1 more source

Immunohistochemical age changes of vagina tissues in women with pelvic prolaps

Репродуктивная эндокринология, 2023
Research objectives: to study age-related changes in the structure of vaginal tissues in women with pelvic prolapse (PP). Materials and methods. The structure of the vaginal wall was studied in 29 women with PP, who were divided into three groups: the ...
R.A. Safonov, V.Y. Prokopiuk, O.V. Hryshchenko, O.S. Prokopiuk, V.V. Lazurenko, M.H. Hryshchenko, V.Y. Parashchuk   +6 more
doaj   +1 more source

Hematopoietic progenitor cell content of vertebral body marrow used for combined solid organ and bone marrow transplantation [PDF]

, 1995
While cadaveric vertebral bodies (VB) have long been proposed as a suitable source of bone marrow (BM) for transplantation (BMT), they have rarely been used for this purpose. We have infused VB BM immediately following whole organ (WO) transplantation to
Ball, ED, Fontes, PA, Rao, AS, Ricordi, C, Rybka, WB, Starzl, TE, Winkelstein, A   +6 more
core   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

Advanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee, Stefanie S. M. Meier, Sara Trujillo, Andreas Möglich, Shrikrishnan Sankaran   +4 more
wiley   +1 more source

Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Case Report

Central Asian Journal of Medical Sciences, 2019
Objectives: Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is a rare benign vascular lesion with unknown etiology. Our purpose is to present our experience with this condition and review the available literature regarding it. Methods:
Sayamaa Lkhagvadorj, Sanchin Urjin, Usukhbayar Erdenebaatar, Batsaikhan Bat-Erdene   +3 more
doaj   +1 more source