Results 61 to 70 of about 220,523 (312)
Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Case Report
Central Asian Journal of Medical Sciences, 2019 Objectives: Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is a rare benign vascular lesion with unknown etiology. Our purpose is to present our experience with this condition and review the available literature regarding it. Methods:
Sayamaa Lkhagvadorj +3 more
doaj +1 more source
On the markers for schizophrenia
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2021 Summary. The study of various markers indicating an imbalance in both the neurotransmitter and immune systems observed in patients with schizophrenia is currently of great scientific and practical interest.
A. N. Erichev +4 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Impaired bone marrow homing of cytokine-activated CD34+ cells in the NOD/SCID model [PDF]
, 2004 The reduced engraftment potential of hematopoietic stem/progenitor cells (HSPCs) after exposure to cytokines may be related to the impaired homing ability of actively cycling cells. We tested this hypothesis by quantifying the short-term horning of human
Pizzey, AR +8 more
core
Advanced Healthcare Materials, EarlyView.We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
wiley +1 more source
Archives of Medical Science, 2019 Introduction Telocytes (TCs), also called interstitial Cajal-like cells (ICLC), CD34+ cells or PDGFR+ cells (platelet-derived growth factor receptor positive cells), a new type of cell of mesenchymal origin, were described over one decade ago.
Veronika Aleksandrovych +6 more
doaj +1 more source
A Mouse Model for Studying Stem Cell Effects on Regeneration of Hair Follicle Outer Root Sheaths
Open Life Sciences, 2020 Stem cells hold promise for treating hair loss. Here an in vitro mouse model was developed using outer root sheaths (ORSs) isolated from hair follicles for studying stem cell-mediated dermal papillary regeneration.
Guo Jingxu +6 more
doaj +1 more source
CD34 neural progenitor cells in glioblastoma multiforme
Glioma, 2020 Background and Aim: Glioblastoma multiforme (GBM) is a World Health Organization (WHO) Grade IV malignant tumor with astrocytic differentiation. Despite medical advances over the past few decades, the life expectancy of patients with GBM has remained ...
Reneta Georgieva +3 more
doaj +1 more source
CD34 Is a Ligand for Vascular Selectins on Human Hematopoietic Stem/Progenitor Cells
, 2015 The cell surface glycoprotein CD34 is widely recognized as a marker of hematopoietic stem/progenitor cells (HSPCs), but its physiological role on HSPCs remains elusive. Although CD34 is well recognized for mediating homing of L-selectin+ naïve T cells to
Abu Samra, Dina Bashir Kamil
core +1 more source
Advanced Science, EarlyView.The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng +15 more
wiley +1 more source