Results 71 to 80 of about 207,399 (316)

Association between height and circulating CD34-positive cells taken into account for the influence of enhanced production among elderly Japanese men: a cross-sectional study

, 2019
Recent studies have revealed an inverse association between height and cardiovascular disease and that endothelial progenitor cells(CD34-positive cells) contribute to vascular maintenance, which is associated with cardiovascular disease. However,evidence
Noguchi, Yuko, Kawashiri, Shin-Ya, Tamai, Mami, Maeda, Takahiro, Nagayoshi, Mako, Arima, Kazuhiko, Kiyoura, Kairi, Yamanashi, Hirotomo, Koyamatsu, Jun, Fukui, Shoichi, Shimizu, Yuji   +10 more
core   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Myeloid Sarcoma: A Series of Five Cases from a Tertiary Care Centre in Tamil Nadu, India [PDF]

Journal of Clinical and Diagnostic Research
Myeloid Sarcoma (MS) constitutes a rare extramedullary manifestation characterised by the clonal proliferation of myeloid precursor cells. It may present in association with Acute Myeloid Leukaemia (AML), Myelodysplastic Syndromes (MDS), or ...
D Saranya, S Preetha, P Vijayabaskar, S Gomathi, P Vinodhini   +4 more
doaj   +1 more source

Functional activity of murine CD34+and CD34− hematopoietic stem cell populations

Experimental Hematology, 1999
The transmembrane glycoprotein CD34 is expressed on human hematopoietic stem cells and committed progenitors in the bone marrow, and CD34-positive selection currently is used to isolate bone marrow repopulating cells in clinical transplantation protocols.
D S, Donnelly, D, Zelterman, S, Sharkis, D S, Krause   +3 more
openaire   +2 more sources

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

Advanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li, Xin Xing, Beicheng Du, Myles Zhou, Austin Z. Chen, Mary Archer, Chunbao Rao, Manyu Zhu, Masnsen Cherief, Aaron W. James   +9 more
wiley   +1 more source

Distribution of Stromal Cell Subsets in Cultures from Distinct Ocular Surface Compartments

Journal of Ophthalmic & Vision Research, 2020
Purpose: To reveal the phenotypic differences between human ocular surface stromal cells (hOSSCs) cultured from the corneal, limbal, and scleral compartments. Methods: A comparative analysis of cultured hOSSCs derived from four unrelated donors was
Lei Liu, Ying Yu, Qiuyue Peng, Simone R Porsborg, Frederik M Nielsen, Annemette Jørgensen, Anni Grove, Chris Bath, Jesper Hjortdal, Ole B Christiansen, Trine Fink, Vladimir Zachar   +11 more
doaj   +1 more source

Absence of a CD34− hematopoietic precursor population in recipients of CD34+ stem cell transplantation [PDF]

Bone Marrow Transplantation, 2001
The purified CD34(+) cell fraction has been used for hematopoietic stem cell transplantation since they were demonstrated to have long-term reconstituting ability. Therefore, the potential effects of CD34(-) stem cells on the clinical course have been a major concern in recipients of CD34(+)-selected transplantation. To address this concern, we used an
S, Kato, K, Ando, Y, Nakamura, Y, Muguruma, T, Sato, H, Yabe, M, Yabe, K, Hattori, Y, Yasuda, T, Hotta   +9 more
openaire   +2 more sources

Expansão ex vivo de células-tronco/progenitoras hematopoiéticas de sangue de cordão umbilical e placentário [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014.As Células-tronco progenitoras hematopoiéticas (CTPHs) do sangue de cordão umbilical e placentário (SCUP ...
Benedetti, Aloisio Luiz
core  

Characterization of CD34-deficient myofibroblastomas of the breast.

, 2017
Mammary myofibroblastoma is a benign spindle cell tumor that can show variable morphologic patterns and lines of differentiation. Diffuse and strong immunohistochemical expression of CD34 is a characteristic of myofibroblastoma and greatly aids in ...
Subramaniyam, Shivakumar, Yi-Fang Liu, Mosquera, Juan Miguel, Juan Miguel Mosquera, Paula S. Ginter, Shin, Sandra J, Jaclyn Croyle, Ginter, Paula S, Timothy M. D'Alfonso, Shivakumar Subramaniyam, Liu, Yi-Fang, Mark A. Rubin, Rubin, Mark Andrew, D'Alfonso, Timothy M, Croyle, Jaclyn, Sandra J. Shin   +15 more
core   +1 more source