Results 91 to 100 of about 71,651 (313)

Binding of Plasmodium falciparum to CD36 can be shielded by the glycocalyx [PDF]

open access: yes, 2017
Background Plasmodium falciparum-infected erythrocytes sequester in the microcirculation due to interaction between surface-expressed parasite proteins and endothelial receptors.
Hempel, Casper   +3 more
core   +3 more sources

Unraveling genotype–phenotype associations and predictive modeling of outcome in acute myeloid leukemia

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute myeloid leukemia (AML) comprises 32% of adult leukemia cases, with a 5‐year survival rate of only 20–30%. Here, the immunophenotypic landscape of this heterogeneous malignancy is explored in a single‐center cohort using a novel quantitative computational pipeline.
Artuur Couckuyt   +10 more
wiley   +1 more source

The Role of Osteopontin (OPN) in Regulating Microglia Phagocytosis in Nervous System Diseases

open access: yesJournal of Integrative Neuroscience
Phagocytosis is the process by which certain cells or organelles internalise foreign substances by engulfing them and then digesting or disposing of them. Microglia are the main resident phagocytic cells in the brain.
Pengpeng Li, Zhengxin Tao, Xudong Zhao
doaj   +1 more source

Comparative Studies of Vertebrate Platelet Glycoprotein 4 (CD36)

open access: yesBiomolecules, 2012
Platelet glycoprotein 4 (CD36) (or fatty acyl translocase [FAT], or scavenger receptor class B, member 3 [SCARB3]) is an essential cell surface and skeletal muscle outer mitochondrial membrane glycoprotein involved in multiple functions in the body. CD36
Roger S. Holmes
doaj   +1 more source

Macrophage-derived upd3 Cytokine causes impaired glucose homeostasis and reduced lifespan in drosophila fed a lipid-rich diet [PDF]

open access: yes, 2014
Long-term consumption of fatty foods is associated with obesity, macrophage activation and inflammation, metabolic imbalance, and a reduced lifespan. We took advantage of Drosophila genetics to investigate the role of macrophages and the pathway(s) that ...
Dionne, MS   +5 more
core   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Study on CD36 gene expression in megakaryocytic lineage derived from umbilical cord blood hematopoietic stem cells cultured in vitro

open access: yesZhongguo shuxue zazhi
[Objective] To elucidate the expression level and transcript structure of the CD36 gene in megakaryocytes cultured in vitro. [Methods] Using umbilical cord blood CD34+ hematopoietic stem cells as the starting point, megakaryocytic lineage cells were ...
XU Fang   +4 more
doaj   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

open access: yesExploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

CD36-mediated immune response and transfusion safety

open access: yesZhongguo shuxue zazhi
Cluster of differentiation 36 (CD36) is a highly glycosylated double transmembrane glycoprotein, which is involved in the inflammatory response and immune regulation of the body.
JIE Xiaomei   +3 more
doaj   +1 more source

Lipoprotein binding preference of CD36 is altered by filipin treatment

open access: yesLipids in Health and Disease, 2008
The class B scavenger receptor CD36 binds multiple ligands, including oxidized and native lipoprotein species. CD36 and the related receptor SR-B1 have been localized to caveolae, domains that participate in cell signaling, transcytosis, and regulation ...
Chu Wuying, Zhang Jianshe, Crandall Ian
doaj   +1 more source

Home - About - Disclaimer - Privacy