Results 101 to 110 of about 77,752 (295)

Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway. [PDF]

open access: yes, 2008
The liver is responsible for key metabolic functions, including control of normal homoeostasis in response to diet and xenobiotic metabolism/detoxification.
Finn, Robert   +3 more
core   +4 more sources

Cellular cholesterol regulates expression of the macrophage type B scavenger receptor, CD36

open access: yesJournal of Lipid Research, 1999
CD36, the macrophage type B scavenger receptor, binds and internalizes oxidized low density lipoprotein (OxLDL), and may potentially play a role in the development of atherosclerosis.
Jihong Han   +3 more
doaj   +1 more source

Platelet-Induced Clumping of Plasmodium falciparum–Infected Erythrocytes from Malawian Patients with Cerebral Malaria—Possible Modulation In Vivo by Thrombocytopenia [PDF]

open access: yes, 2008
Platelets may play a role in the pathogenesis of human cerebral malaria (CM), and they have been shown to induce clumping of Plasmodium falciparum–parasitized red blood cells (PRBCs) in vitro.
Barnwell JW   +18 more
core   +1 more source

Oleoylethanolamide regulates intestinal stem cell activity and villus size via PPARα signaling pathway

open access: yesiMetaOmics, EarlyView.
First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang   +9 more
wiley   +1 more source

Immunometabolic profiling of human monocytes in response to lipid exposure

open access: yesRomanian Journal of Laboratory Medicine
Monocytes are central in inflammation and atherogenesis. Postprandial lipemia is a known pro-atherogenic state, yet its impact on monocyte activation remains incompletely understood.
Mănescu Ion Bogdan   +5 more
doaj   +1 more source

Functional roles of membrane glycoprotein CD36

open access: yesPlatelets, 1996
Cell-cell and cell-extracellular matrix interactions are mediated by a number of membrane glycoproteins. On the basis of structural homologies, several families of cell adhesion molecules (integrins, selectins, immunoglobulins, cadherins, leucine-rich glycoproteins) have been established.
L, Daviet, J L, McGregor
openaire   +2 more sources

Schisantherin A: Remodeling Gut Microbiota to Activate the Gut–Immune–Neural–Adipose Axis for Thermogenesis

open access: yesiNew Medicine, EarlyView.
ABSTRACT The global obesity epidemic necessitates safe and effective strategies to enhance energy expenditure. Schisantherin A (Sin A), a lignan derived from Schisandra chinensis, has demonstrated metabolic benefits, yet its systemic mechanism remains unclear.
Ling Yin
wiley   +1 more source

Whole-genome polymorphism of CD36 by third-generation sequencing technology

open access: yesZhongguo shuxue zazhi
[Objective] To analyze CD36 gene by PacBio Sequel Ⅱ the third-generation sequencing technology (TGS), including non-coding sequence, and to investigate the molecular mechanism of CD36 deficiency.
LIU Jing   +6 more
doaj   +1 more source

CD36 deletion reduces VLDL secretion, modulates liver prostaglandins, and exacerbates hepatic steatosis in ob/ob mice[S]

open access: yesJournal of Lipid Research, 2013
Recent findings described the role of CD36-mediated signaling in regulating cellular calcium and the release of various bioactive molecules, including the prostaglandins, neurotransmitters, cholecystokinin, and secretin. Here we document the role of CD36
Fatiha Nassir   +3 more
doaj   +1 more source

β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase [PDF]

open access: yes, 2004
β-Amyloid (βA) peptide is strongly implicated in the neurodegeneration underlying Alzheimer's disease, but the mechanisms of neurotoxicity remain controversial. This study establishes a central role for oxidative stress by the activation of NADPH oxidase
Abramov, A.Y.   +2 more
core  

Home - About - Disclaimer - Privacy