Results 31 to 40 of about 81,560 (343)

CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis

Cell Death and Disease, 2022
A major cause of proteinuria in lupus nephritis (LN) is podocyte injury, and determining potential therapeutic targets to prevent podocyte injury is important from a clinical perspective in the treatment of LN.
Fu Lv, Ying-jie He, Hongde Xu, Yongchun Li, Li-pei Han, Lijie Yan, H. Lang, Yafei Zhao, Zhanzheng Zhao, Yu-feng Qi   +9 more
semanticscholar   +1 more source

Genome-wide Identification and Bioinformatics Analysis of Scavenger Receptor Gene Family in Plutella xylostella

Guangdong nongye kexue, 2023
【Objective】The resistance of Plutella xylostella to chemical insecticides is increasing year by year, which makes RNAi (RNA interference) pesticides widely concerned. The P.
Jianbin TAN, Jin XU, Peiqiong SHI, Hongkai ZHOU   +3 more
doaj   +1 more source

Upregulation of CD36, a Fatty Acid Translocase, Promotes Colorectal Cancer Metastasis by Increasing MMP28 and Decreasing E-Cadherin Expression

Cancers, 2022
Simple Summary Colorectal cancer is the second leading cause of cancer-related death in the world. Upregulation of fatty acid metabolism is a hallmark of cancer and recent studies demonstrate that blocking fatty acid uptake is a promising therapeutic ...
J. Drury, P. Rychahou, Courtney O Kelson, Mariah E. Geisen, Yuanyuan Wu, Daheng He, Chi Wang, Eun Y. Lee, B. Evers, Yekaterina Y. Zaytseva   +9 more
semanticscholar   +1 more source

Deciphering the Role of CD36 in Gestational Diabetes Mellitus: Linking Fatty Acid Metabolism and Inflammation in Disease Pathogenesis. [PDF]

J Inflamm Res
Li Huang,1– 3,* Tong Zhang,4,* Yuanyuan Zhu,5 Xueling Lai,6 Hualin Tao,1– 3 Yuhan Xing,5 Zhaoyinqian Li1– 3 1Department of Laboratory Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of China ...
Huang L, Zhang T, Zhu Y, Lai X, Tao H, Xing Y, Li Z.   +6 more
europepmc   +2 more sources

Dietary sucrose regulates the expression of the Cd36 gene in hepatic tissue of rats with obesity and Non Alcoholic Fatty Liver Disease (NAFLD)

Biomedical Papers, 2018
Aim: To evaluate the mRNA expression levels of Cd36 in adipose and hepatic tissues, in rats with NAFLD after the consumption of sucrose for 10 and 20 weeks.
Rodolfo Quintana Castro, Ida Soto Rodriguez, Rosa A. Deschamps Lago, Peter Grube Pagola, Jorge Rodriguez Antolin, Adriana Peres Quintal, Jaime Rivera Rivera, Alfonso Alexander Aguilera   +7 more
doaj   +1 more source

Hypoxia-Induced CD36 Expression in Gastric Cancer Cells Promotes Peritoneal Metastasis via Fatty Acid Uptake

Annals of Surgical Oncology, 2022
Background The lipid scavenger receptor cluster of differentiation 36 (CD36) has been shown to have a pro-metastatic function in several cancers. Adipose tissue, a favorable site for peritoneal metastasis (PM) from gastric cancer (GC), promotes this ...
Tatsuya Aoki, J. Kinoshita, Sei-ichi Munesue, Toshihide Hamabe-Horiike, Takahisa Yamaguchi, Yusuke Nakamura, K. Okamoto, H. Moriyama, Keishi Nakamura, S. Harada, Yasuhiko Yamamoto, N. Inaki, S. Fushida   +12 more
semanticscholar   +1 more source

Treatment of growth hormone attenuates hepatic steatosis in hyperlipidemic mice via downregulation of hepatic CD36 expression

Animal Cells and Systems, 2020
The recombinant human growth hormone (GH) has been used for the treatment of growth hormone deficiency (GHD) and diverse short stature state, and its physiological and therapeutic effects are well documented.
Hyung Seok Jang, Kyeongdae Kim, Mi-Ran Lee, Shin-Hye Kim, Jae-Hoon Choi, Mi Jung Park   +5 more
doaj   +1 more source

Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells

Nature Communications, 2021
Disruption of lymphatic lipid transport is linked to obesity and type 2 diabetes (T2D), but regulation of lymphatic vessel function and its link to disease remain unclear. Here we show that intestinal lymphatic endothelial cells (LECs) have an increasing
Vincenza Cifarelli, Sila Appak-Baskoy, V. Peche, Andrew Kluzak, Trevor M. Shew, Ramkumar Narendran, Kathryn Pietka, M. Cella, Curtis W Walls, R. Czepielewski, Stoyan Ivanov, G. Randolph, H. Augustin, N. Abumrad   +13 more
semanticscholar   +1 more source

CD36 promotes NLRP3 inflammasome activation via the mtROS pathway in renal tubular epithelial cells of diabetic kidneys

Cell Death and Disease, 2021
Tubulointerstitial inflammation plays a key role in the pathogenesis of diabetic nephropathy (DN). Interleukin-1β (IL-1β) is the key proinflammatory cytokine associated with tubulointerstitial inflammation.
Yanjuan Hou, Qian Wang, Baosheng Han, Yiliang Chen, X. Qiao, Lihua Wang   +5 more
semanticscholar   +1 more source

CD36: Implications in cardiovascular disease [PDF]

The International Journal of Biochemistry & Cell Biology, 2007
CD36 is a broadly expressed membrane glycoprotein that acts as a facilitator of fatty acid uptake, a signaling molecule, and a receptor for a wide range of ligands, including apoptotic cells, modified forms of low density lipoprotein, thrombospondins, fibrillar beta-amyloid, components of Gram positive bacterial walls and malaria infected erythrocytes.
Roy L. Silverstein, Maria Febbraio
openaire   +2 more sources