Immature Dendritic Cells Phagocytose Apoptotic Cells via αvβ5 and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes [PDF]
The Journal of Experimental Medicine, 1998 Dendritic cells, but not macrophages, efficiently phagocytose apoptotic cells and cross-present viral, tumor, and self-antigens to CD8+ T cells. This in vitro pathway corresponds to the in vivo phenomena of cross-priming and cross-tolerance.
M. Albert +6 more
semanticscholar +8 more sources
Autophagy protein ATG5 regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells [PDF]
Autophagy, 2019 Macroautophagy/autophagy has been implicated in cytoplasmic and viral antigen presentation on major histocompatibility complex (MHC) class II molecules. However, the role of autophagy in the presentation of phagocytized tumor-associated antigens in vivo ...
D. Oh, H. Lee
semanticscholar +5 more sources
Phenotypic and functional changes in blood monocytes following adherence to endothelium. [PDF]
PLoS ONE, 2012 ObjectiveBlood monocytes are known to express endothelial-like genes during co-culture with endothelium. In this study, the time-dependent change in the phenotype pattern of primary blood monocytes after adhering to endothelium is reported using a novel ...
Colin Tso, Kerry-Anne Rye, Philip Barter
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The role and mechanism of action of endoplasmic reticulum transmembrane protein 166 in liver lipid metabolism [PDF]
精准医学杂志Objective To investigate the role and specific molecular mechanism of action of endoplasmic reticulum transmembrane protein 166 (TMEM166) in liver lipid metabolism. Methods Tmem166flox/flox mice were crossed with Alb-Cre mice, and the offspring Tmem166+/+
LI Lianhui, YANG Di, ZANG Kailai, SUN Yani, DU Qiyuan, LI Ning
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A case of platelet transfusion refractoriness due to anti-CD36 with a successful treatment outcome
Immunohematology, 2019 Antibodies (Abs) against antigens on platelets (PLTs), including glycoprotein IV (CD36), can cause PLT refractoriness. Transfusing PLTs to patients with anti-CD36 is challenging because of the rarity of CD36-negative (CD36–) donors and the possibility of
S. Khatri, B. Curtis, C. Yamada
semanticscholar +1 more source
Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. [PDF]
PLoS ONE, 2015 The initiation of adaptive immune responses to protein antigens has to be preceded by their uptake by antigen presenting cells and intracellular proteolytic processing.
Rafał Biedroń +3 more
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Nutrients, 2022 As of late, evidence has been emerging that the Maillard reaction (MR, also referred to as glycation) affects the structure and function of food proteins.
Daniela Briceno Noriega +7 more
semanticscholar +1 more source
Redox Biology, 2021 Macrophages are innate immune cells that internalize and present exogenous antigens to T cells via MHC class II proteins. They operate at sites of infection in a highly inflammatory environment, generated in part by reactive oxygen species, in particular
Agnes Ulfig +5 more
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CD24, CD27, CD36 and CD302 gene expression for outcome prediction in patients with multiple myeloma
OncoTarget, 2017 Multiple myeloma (MM) is a B cell neoplasia characterized by clonal plasma cell (PC) proliferation. Minimal residual disease monitoring by multi-parameter flow cytometry is a powerful tool for predicting treatment efficacy and MM outcome.
E. Alaterre +10 more
semanticscholar +1 more source
Revista Brasileira de Hematologia e Hemoterapia, 2012 Chronic myelomonocytic leukemia is a clonal stem cell disorder that is characterized mainly by absolute peripheral monocytosis. This disease can present myeloproliferative and myelodysplastic characteristics.
Iris Mattos Santos +2 more
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