Results 1 to 10 of about 1,027,672 (251)

CD36 family members are TCR-independent ligands for CD1 antigen–presenting molecules [PDF]

Science Immunology, 2021
CD1 molecules bind CD36 family members, and blocking this interaction facilitates staining and study of CD1-restricted T cells. CD36 blockade provides CD1 clarity A subset of T cells detects lipids presented by CD1c.
Nicholas A. Gherardin, Samuel J. Redmond, Hamish E. G. McWilliam, Catarina F. Almeida, Katherine H. A. Gourley, Rebecca Seneviratna, Shihan Li, Robert De Rose, Fiona Ross, Catriona V. Nguyen-Robertson, Shian Su, Matthew E. Ritchie, José A. Villadangos, D. Branch Moody, Daniel G. Pellicci, Adam P. Uldrich, Dale I. Godfrey   +16 more
semanticscholar   +9 more sources

Improvement of Anti-CD36 Antibody Detection via Monoclonal Antibody Immobilization of Platelet Antigens Assay by Using Selected Monoclonal Antibodies

Annals of Laboratory Medicine, 2022
Antibodies against human CD36 are responsible for several immune-mediated disorders. The detection of anti-CD36 antibodies using the standard monoclonal antibody (mAb) immobilization of platelet antigens (MAIPA) assay is hampered by a high frequency of ...
Xiuzhang Xu, Dawei Chen, Xin Ye, Wenjie Xia, Yuan Shao, Jing Deng, Yangkai Chen, Haoqiang Ding, Jing Liu, Yaori Xu, Sentot Santoso, Yongshui Fu   +11 more
semanticscholar   +5 more sources

Immature Dendritic Cells Phagocytose Apoptotic Cells via αvβ5 and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes [PDF]

The Journal of Experimental Medicine, 1998
Dendritic cells, but not macrophages, efficiently phagocytose apoptotic cells and cross-present viral, tumor, and self-antigens to CD8+ T cells. This in vitro pathway corresponds to the in vivo phenomena of cross-priming and cross-tolerance.
Matthew L. Albert, S. Frieda A. Pearce, Loise M. Francisco, Birthe Sauter, Pampa Roy, Roy L. Silverstein, Nina Bhardwaj   +6 more
semanticscholar   +9 more sources

Autophagy protein ATG5 regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells [PDF]

Autophagy, 2019
Macroautophagy/autophagy has been implicated in cytoplasmic and viral antigen presentation on major histocompatibility complex (MHC) class II molecules. However, the role of autophagy in the presentation of phagocytized tumor-associated antigens in vivo ...
Dong Sun Oh, Heung Kyu Lee
semanticscholar   +5 more sources

Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance [PDF]

Immunity, 2018
The development of T cell tolerance in the thymus requires the presentation of host proteins by multiple antigen-presenting cell (APC) types. However, the importance of transferring host antigens from transcription factor AIRE-dependent medullary thymic epithelial cells (mTECs) to bone marrow (BM) APCs is unknown.
Justin S. A. Perry, Emilie V. Russler-Germain, You W. Zhou, Whitney E. Purtha, Matthew Cooper, Jaebok Choi, Mark A. Schroeder, Vanessa Salazar, Takeshi Egawa, Byeong-Chel Lee, Nada A. Abumrad, Brian Kim, Mark S. Anderson, John F. DiPersio, Chyi‐Song Hsieh   +14 more
semanticscholar   +12 more sources

Cytoadherence and virulence - the case of Plasmodium knowlesi malaria [PDF]

Malaria Journal, 2012
Background Cytoadherence of infected red blood cells to brain endothelium is causally implicated in malarial coma, one of the severe manifestations of falciparum malaria.
Fatih Farrah A, Siner Angela, Ahmed Atique, Woon Lu, Craig Alister G, Singh Balbir, Krishna Sanjeev, Cox-Singh Janet   +7 more
doaj   +6 more sources

Neonatal Intracranial Hemorrhage with a Dramatic Outcome Due to Maternal Anti CD36 Antibodies

Reports, 2019
Fetal/neonatal allo-immune thrombocytopenia (FNAIT) results from maternal immunization against fetal platelet-specific antigens (HPA) inherited from the father. Most cases involve HPA located on glycoproteins (GP) IbIX, IaIIa and IIbIIIa.
Gérald Bertrand, Virginie Renac, Marie-Christine Lefaix, Carl Nivet, Elise Trudel, Lucie Richard   +5 more
doaj   +2 more sources

Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System [PDF]

Diabetes & Metabolism Journal
Type 2 diabetes mellitus (T2DM) is marked by chronic hyperglycemia, gradually worsening β-cell failure, and insulin resistance. Glucotoxicity and oxidative stress cause β-cell failure by increasing reactive oxygen species (ROS) production, impairing ...
Il Rae Park, Yong Geun Chung, Kyu Chang Won   +2 more
doaj   +2 more sources

Management challenge of a rare concomitant platelet glycoprotein IV/CD36 and IIb/IIIa deficiencies: Case illustration. [PDF]

Transfusion
Abstract Introduction/Background Platelet membrane glycoproteins (GPs) serve several functions, the most significant of which is their role in primary hemostasis. Among these, GP IIb/IIIa is the primary fibrinogen receptor and is essential for platelet aggregation.
Sekayan T, Allen ES, Kopko P, Stephens LD, Zhao M, Curtis BR, Sullivan MJ, Trapp-Stamborski V, von Drygalski A.   +8 more
europepmc   +2 more sources

Intrathymic Regulation of Dendritic Cell Subsets and Their Contributions to Central Tolerance. [PDF]

Immunol Rev
ABSTRACT Thymic dendritic cells (DCs) are critical mediators of central tolerance, cooperating with medullary thymic epithelial cells (mTECs) and B cells to establish T‐cell self‐tolerance to the proteome. The DC compartment is highly heterogeneous and is comprised of three major subsets, plasmacytoid dendritic cells (pDCs) and two conventional ...
Calindi A, Ehrlich LIR.
europepmc   +2 more sources