Results 21 to 30 of about 1,186,345 (240)

Structural, functional, and antigenic differences between bovine heart endothelial CD36 and human platelet CD36.

Journal of Biological Chemistry, 1990
Endothelial cell CD36 (glycoprotein IV) has been purified from bovine heart tissue by detergent partitioning and immunoaffinity chromatography. Bovine CD36 differs from human CD36 in its apparent mass (85 versus 88 kDa), primary structure, and immunological cross-reactivity.
D E, Greenwalt, K W, Watt, T, Hasler, R J, Howard, S, Patel   +4 more
openaire   +2 more sources

Dendritic cells in plasmodium infection [PDF]

, 2008
Infection with Plasmodium parasites (malaria) contributes greatly to morbidity and mortality in affected areas. Interaction of the protozoan with the immune system has a critical role in the pathogenesis of the disease, but may also hold a key to ...
Alonso, Bejon, Britta C Urban, Bruna-Romero, deWalick, Greenwood, Park, Patel, Perry, Pichyangkul, Pouniotis, Skorokhod, Stephen M Todryk, Todryk, Wong, Wykes   +15 more
core   +2 more sources

Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance.

Immunity, 2018
Summary The development of T cell tolerance in the thymus requires the presentation of host proteins by multiple antigen-presenting cell (APC) types. However, the importance of transferring host antigens from transcription factor AIRE-dependent medullary
Justin S. A. Perry, Emilie V Russler-Germain, You W. Zhou, Whitney E. Purtha, M. Cooper, Jaebok Choi, M. Schroeder, Vanessa Salazar, Takeshi Egawa, Byeong‐Chel Lee, N. Abumrad, Brian S. Kim, Mark S. Anderson, J. Dipersio, C. Hsieh   +14 more
semanticscholar   +1 more source

Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]

, 2012
BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Carl Cotman, Erik Hrabovszky, Imre Kalló, István Likó, Miklós Sárvári, Nicole Berchtold, Norbert Solymosi, Sárvári, Miklós, Zsolt Liposits   +8 more
core   +2 more sources

Alterations in Lysosome Homeostasis in Lipid-Related Disorders: Impact on Metabolic Tissues and Immune Cells

Frontiers in Cell and Developmental Biology, 2021
Lipid-related disorders, which primarily affect metabolic tissues, including adipose tissue and the liver are associated with alterations in lysosome homeostasis.
Fernanda Cabrera-Reyes, Fernanda Cabrera-Reyes, Claudia Parra-Ruiz, Claudia Parra-Ruiz, María Isabel Yuseff, Silvana Zanlungo   +5 more
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System [PDF]

Diabetes & Metabolism Journal
Type 2 diabetes mellitus (T2DM) is marked by chronic hyperglycemia, gradually worsening β-cell failure, and insulin resistance. Glucotoxicity and oxidative stress cause β-cell failure by increasing reactive oxygen species (ROS) production, impairing ...
Il Rae Park, Yong Geun Chung, Kyu Chang Won   +2 more
doaj   +1 more source

Immunomodulatory cross-talk between conjunctival goblet cells and dendritic cells. [PDF]

PLoS ONE, 2015
Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from environmental agents or pathogens via expression and secretion of soluble mucins.
Laura Contreras-Ruiz, Sharmila Masli
doaj   +1 more source

CD36 Is Differentially Expressed on B Cell Subsets during Development and in Responses to Antigen [PDF]

The Journal of Immunology, 2008
Abstract Of a number of mAbs made by immunization with sort-purified marginal zone (MZ) B cells, one was shown to recognize the mouse scavenger receptor CD36. Although CD36 is expressed by most resting MZ B cells and not by follicular and B1 B cells, it is rapidly induced on follicular B cells in vitro following TLR and CD40 stimulation.
Won, W, Bachmann, M, Kearney, J
openaire   +3 more sources

The role of Plasmodium falciparum var genes in malaria in pregnancy [PDF]

, 2004
Sequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected ...
Andrews, Baruch, Beeson, Beeson, Beeson, Brabin, Buffet, Chen, Costa, Creasey, Dorman, Duffy, Duffy, Flick, Freitas-Junior, Fried, Fried, Fried, Fried, Gardner, Jensen, Kyes, Kyes, Lekana Douki, McCormick, McGregor, Menendez, Menendez, Nosten, O'Neil-Dunne, Reeder, Reeder, Ricke, Rowe, Rowe, Salanti, Salanti, Shulman, Smith, Smith, Smith, Smith, Staalsoe, Staalsoe, Steketee, Su, Suguitan, Taylor, Taylor, Walter, Ward, Winter   +51 more
core   +1 more source