Objectives Rheumatoid arthritis (RA) is usually preceded and likely mediated by autoantibodies to citrullinated proteins (ACPAs) that recognize citrulline residues on multiple proteins. Conversion of arginine into citrulline is performed by enzymes called peptidyl arginine deiminases (PADs).
Philippe P. Pagni+10 more
wiley +1 more source
Smoking and presence of human papillomavirus correlates with lymphocyte density in the stroma of penile squamous cell carcinoma. [PDF]
Mumba C+3 more
europepmc +1 more source
[Total lymphocyte-count as a substitute for CD4 positive lymphocyte determination].
G, Rey, G, Tate, A, Malbrán
openaire +1 more source
Engineering antibodies with cancer‐associated binding sites
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian+4 more
wiley +1 more source
Clinical features and risk factors for Epstein-Barr virus-associated encephalitis: a retrospective cohort study. [PDF]
Liu Z+6 more
europepmc +1 more source
Analysis of Differences in Lymphocyte Subsets and CD4+ T Cells Immune Activation Between Re-detectable Positive and Non-re-detectable Positive COVID-19 Convalescent Patients [PDF]
Huang Zhi Min+9 more
openalex +1 more source
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan+12 more
wiley +1 more source
Intratumoral CD8+ tumor-infiltrating lymphocytes as prognostic predictors in radio-chemoradiotherapy-treated nasopharyngeal carcinoma. [PDF]
Li X+7 more
europepmc +1 more source
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang+7 more
wiley +1 more source
An immunohistological analysis of 13 idiopathic subglottic stenosis (iSGS) excisions: a single centre study. [PDF]
Nagaroor A, Höller S, Franzen DP.
europepmc +1 more source