Results 161 to 170 of about 35,706 (250)
Aggregate, Volume 7, Issue 3, March 2026.Coated with cell membrane, CM‐NC@NF evades immune clearance, accumulates via EPR effect, and upon laser irradiation, generates ROS to induce ferroptosis‐like deth and photothermal therapy, enhancing cancer cell death. ABSTRACT Gold nanocluster (NC)‐induced ferroptosis has emerged as a promising method for malignant tumors. However, the immune clearance
Qixuan Wang +8 more
wiley +1 more source
Hypoimmunogenic Derivatives of Induced Pluripotent Stem Cells Evade Immune Rejection in Fully Immunocompetent Allogeneic Recipients [PDF]
, 2020 Davis, M +12 more
core
Cancer Medicine, Volume 15, Issue 3, March 2026.ABSTRACT In colorectal cancer (CRC), circulating tumour cells (CTCs) employ genetic alterations to dodge the body's immune system. These alterations occur in specific “driver” genes, including KRAS, BRAF, p53, MYC, APC and PTEN. Changes in these genes can control how the tumour interacts with the immune system and influence the expression of immune ...
Sharmin Aktar +5 more
wiley +1 more source
iMetaOmics, Volume 3, Issue 1, March 2026.Schematic of the study design. In this study, we developed a comprehensive unfolded protein response (UPR) gene signature and applied it to systematically characterize the UPR landscape across multiple cancer types. By integrating bulk and single‐cell transcriptomic data, we revealed substantial inter‐ and intra‐tumoral heterogeneity in UPR activity ...
Xinyu Yang +8 more
wiley +1 more source
Extracellular Vesicles‐Functionalized Biomaterials for Oral Disease Theragnostics
MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.Combining EVs with biomaterials enables sustained, targeted delivery and overcomes traditional limitations. EVs show great promise in diagnosing and treating oral diseases, and could transform oral health management strategies. ABSTRACT Oral diseases impair oral function and are closely linked to various systemic conditions.
Zhe Zhao, Yiyu Zeng, Rui Liu, Xuemei Qiu
wiley +1 more source
CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling
Med Research, Volume 2, Issue 1, Page 106-129, March 2026.CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li +8 more
wiley +1 more source
The SIRP family: from structural diversity and signaling mechanisms to implications in immune-related disease targeted therapeutics. [PDF]
Front ImmunolJin Y +6 more
europepmc +1 more source
Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu +5 more
wiley +1 more source