Results 161 to 170 of about 38,316 (246)

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

MedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao, Xiaojie Qu, Yiqi Wang, Dan Huang, Huiling Zhang, Mingyuan Dong, Han Sun, Zhaogang Yang, Xuefeng Li   +8 more
wiley   +1 more source

CD47 is a negative regulator of intestinal epithelial cell self-renewal following DSS-induced experimental colitis [PDF]

, 2020
Yueqin He, Xinlei Sun, Weiwei Rong, Rong Yang, Hongwei Liang, Ying Qi, Limin Li, Ke Zen   +7 more
openalex   +1 more source

Targeting CD47 as a Novel Immunotherapy for Breast Cancer [PDF]

, 2022
Can Chen, Runlu Wang, Xi Chen, Yulong Hou, Jingting Jiang   +4 more
openalex   +1 more source

Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application

MedComm, Volume 7, Issue 2, February 2026.
Hydrogels offer an innovative platform for cancer immunotherapy. Through tailorable crosslinking strategies, they form customizable drug delivery platforms that address diverse therapeutic requirements by loading specific immunotherapeutic agents. These systems demonstrate significant clinical potential for precise tumor immunotherapy.
Xiaohua Chen, Shan Wu, Yueyang Zhang, Lilu Feng, Yang Chen, Xuzhao Yang, Ke Men, Jiuqun Zhu, Ming Li   +8 more
wiley   +1 more source

PYGO1 drives gastric cancer progression via the ITGB1/CD47 axis and is therapeutically targeted by pentagalloylglucose [PDF]

Yanjuan Jia, Yaling Li, Yan Li, Yonghong Li, Tao Qu, Zhendong Fu, Yuanyuan Ma, Zhenhao Li, Wanxia Wang, Miao Yu, Xiaojie Jin, Xiaoling Gao, Yongqi Liu   +12 more
openalex   +1 more source

493 Tired and hungry: a potential role for CD47 in T cell exhaustion [PDF]

, 2020
Levi Mangarin, Cailian Liu, Roberta Zappasodi, Pamela M. Holland, Jedd D. Wolchok, Taha Merghoub, Chien‐Huan Weng, Chien‐Huan Weng, David Schröder   +8 more
openalex   +1 more source

A Cellular and Transcriptomic Atlas of the Aged Mouse Hematopoietic System

Aging Cell, Volume 25, Issue 2, February 2026.
Transcriptomic and cellular atlas of peripheral blood mononuclear cells (PBMCs) and stem and progenitor cells of the hematopoietic compartment (HSPCs) of aged C57Bl/6J mice. Analysis shows global alterations related to immune function and identifies potential pathways and cell populations that can be targeted for therapeutic intervention.
Ryan R. White, Kun Xiong, Matthew Wakai, Allison Surian, Christina Adler, Nicole Negron, Min Ni, Tea Shavlakadze, Yu Bai, David J. Glass   +9 more
wiley   +1 more source

Expression and Prognostic Significance of CD47–SIRPA Macrophage Checkpoint Molecules in Colorectal Cancer [PDF]

, 2021
Akane Sugimura‐Nagata, Akira Koshino, Satoshi Inoue, Aya Matsuo-Nagano, Masayuki Komura, Miho Riku, Hideaki Ito, Akihito Inoko, Hideki Murakami, Masahide Ebi, Naotaka Ogasawara, Toyonori Tsuzuki, Satoru Takahashi, Kunio Kasugai, Kenji Kasai, Shingo Inaguma   +15 more
openalex   +1 more source

MYC Promotes Tumorigenesis via Activation of CD47 and PD-L1 [PDF]

, 2016

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Supplementary Figure S7 from Targeting Fc Receptor-Mediated Effects and the “Don't Eat Me” Signal with an Oncolytic Virus Expressing an Anti-CD47 Antibody to Treat Metastatic Ovarian Cancer

, 2023
Lei Tian, Bo Xu, Kun‐Yu Teng, Mihae Song, Zheng Zhu, Yuqing Chen, Jing Wang, Jianying Zhang, Mingye Feng, Balveen Kaur, Lorna Rodriguez, Michael A. Caligiuri, Jianhua Yu   +12 more
openalex   +1 more source