Results 101 to 110 of about 293,060 (357)

Pre-HAART CD4+ T-lymphocytes as biomarkers of post-HAART immune recovery in HIV-infected children with or without TB co-infection

BMC Infectious Diseases, 2020
Background Infection with the Human Immunodeficiency Virus (HIV) dramatically increases the risk of developing active tuberculosis (TB). Several studies have indicated that co-infection with TB increases the risk of HIV progression and death. Sub-Saharan
Vivek Gopalakrishnan, Eliezer Bose, Usha Nair, Yuwei Cheng, Musie Ghebremichael   +4 more
doaj   +1 more source

Accelerated in vivo proliferation of memory phenotype CD4+ T-cells in human HIV-1 infection irrespective of viral chemokine co-receptor tropism. [PDF]

, 2013
CD4(+) T-cell loss is the hallmark of HIV-1 infection. CD4 counts fall more rapidly in advanced disease when CCR5-tropic viral strains tend to be replaced by X4-tropic viruses.
A Kaur, A Llano, A Yates, AN Phillips, Andrea Hegedus, Andrew Worth, B Asquith, Catherine de Lara, D Berhanu, Daniel C. Douek, DC Douek, DC Douek, DC Macallan, DC Macallan, DC Macallan, DC Macallan, DD Ho, Derek Macallan, DL Wallace, EJ Heeregrave, HC Lane, I den Braber, J Embretson, JM Brenchley, JM McCune, JV Giorgi, K Ladell, Karoliina Laamanen, L Cicin-Sain, LJ Picker, M Catalfamo, M Hellerstein, M Koot, MD Hazenberg, MK Hellerstein, MP Davenport, N Brieu, N Vrisekoop, Peter Beverley, R Busch, R Shankarappa, RJ De Boer, RJ De Boer, RM Ribeiro, RM Ribeiro, RS Veazey, SA Handley, TW Chun, V Sanchez, Yan Zhang   +49 more
core   +3 more sources

The Effect of Low CD4+ Lymphocyte Count on the Radiographic Patterns of HIV Patients with Pulmonary Tuberculosis among Nigerians

Tuberculosis Research and Treatment, 2013
Objective. To assess the radiographic features in patients with Human Immunodeficiency Virus (HIV) complicated by pulmonary tuberculosis (PTB), and the association with CD4 lymphocyte count and sputum smear. Method. A prospective study was carried out on
C. Affusim, V. Abah, E. Kesieme, K. Anyanwu, T. Salami, R. Eifediyi   +5 more
semanticscholar   +1 more source

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia, Stephane Rodriguez, Emilie Dugast, Christine Lebrun‐Frenay, Eric Thouvenot, Jérôme de Sèze, Emmanuelle Le Page, Sandra Vukusic, Inès Doghri, Eric Berger, Olivier Casez, Pierre Labauge, Aurélie Ruet, Catarina Raposo, Fabienne Le Frère, Arnaud B. Nicot, Sandrine Wiertlewski, Pierre‐Antoine Gourraud, Laure Michel, Laureline Berthelot, David‐Axel Laplaud   +20 more
wiley   +1 more source

Optimization of an Antiviral Treatment Regimen for Immunological Nonresponders Through HIV-DNA Resistance Testing: A Case Report

Journal of the International Association of Providers of AIDS Care
In August 2012, a 47-year-old male patient was diagnosed with human immunodeficiency virus (HIV) infection, with no other underlying disease or opportunistic infection.
Kun He MS, Xiang Du MS, Qi Cao BM, Mingjun Li MS, Juan Qian BM, Min Liu MS   +5 more
doaj   +1 more source

Use of absolute lymphocyte count or neutrophil ingestion rate of nitroblue tetrazolium (NBT) as alternative index to CD4+T-cell count to initiate ART in the management of HIV/AIDS disease [PDF]

, 2012
The present study was designed to evaluate absolute lymphocyte count or neutrophil ingestion rate of NBT as alternative indices to CD4+ T cell count in the management of HIV/AIDS subjects.
Ahaneku, JE, Ezeani, M, Ifeanyichukwu, M, Igwegbe, AO, Ilika, A, Meludu, SC, Onyenekwe, CC, Ukibe, NR, Ukibe, SN   +8 more
core   +2 more sources

Genetic polymorphisms in CX3CR1 predict HIV-1 disease progression in children independently of CD4+ lymphocyte count and HIV-1 RNA load.

Journal of Infectious Diseases, 2005
BACKGROUND The impact of CX3CR1 polymorphisms on human immunodeficiency virus type 1 (HIV-1) pathogenesis is controversial, with conflicting reports of their role in disease progression in HIV-1-infected adults.
K. Singh, M. Hughes, Jie Chen, S. Spector   +3 more
semanticscholar   +1 more source

Efgartigimod Combined With Steroid Treatment for HAM/TSP: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurological disorder with limited treatment options. We report a 54‐year‐old female with decade‐long, progressive HAM/TSP, previously refractory to rituximab, who experienced worsening spastic paraparesis and neurogenic bladder dysfunction.
Jiahui Zeng, Wotu Tian, Jingran Yang, Yanping Yang, Li Cao, Xinghua Luan   +5 more
wiley   +1 more source

Characteristics, Determinants, and Clinical Relevance of CD4 T Cell Recovery to <500 Cells/µL in HIV Type 1—Infected Individuals Receiving Potent Antiretroviral Therapy [PDF]

, 2017
Background. The CD4 T cell count recovery in human immunodeficiency virus type 1 (HIV-1)—infected individuals receiving potent antiretroviral therapy (ART) shows high variability. We studied the determinants and the clinical relevance of incomplete CD4 T
Battegay, Manuel, Bernasconi, Enos, Cavassini, Matthias, Furrer, Hansjakob, Hirschel, Bernard, Kaufmann, Gilbert R., Ledergerber, Bruno, Opravil, Milos, Perrin, Luc, Rickenbach, Martin, Vernazza, Pietro   +10 more
core  

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

Advanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang, Biying Dong, Jie Chen, Zhenqiang Zhang, Weitong Zeng, Longxiong Liao, Xia Xiong, Xuejun Qin, Xianming Fan   +8 more
wiley   +1 more source