Backgrounds: As there is no published data regarding the response to Anti-retroviral therapy (ART) among HIV patients from Bangladesh. The present study was designed to determine the immunological and virological responses of HIV infected Bangladeshi ...
Sahina Tabassum+4 more
doaj +1 more source
Dynamic models for estimating the effect of HAART on CD4 in observational studies: application to the Aquitaine Cohort study and the Swiss HIV Cohort Study [PDF]
Highly active antiretroviral therapy (HAART) has proved efficient in increasing CD4 counts in many randomized clinical trials. Because randomized trials have some limitations (e.g., short duration, highly selected subjects), it is interesting to assess it using observational studies.
arxiv
Accelerated in vivo proliferation of memory phenotype CD4+ T-cells in human HIV-1 infection irrespective of viral chemokine co-receptor tropism. [PDF]
CD4(+) T-cell loss is the hallmark of HIV-1 infection. CD4 counts fall more rapidly in advanced disease when CCR5-tropic viral strains tend to be replaced by X4-tropic viruses.
A Kaur+49 more
core +3 more sources
Oral manifestations related to CD4 lymphocyte count in HIV-positive patients
Background and aims. The onset of opportunistic infections in HIV-positive patients is generally associated with a low CD4 count. Oral manifestations can be the first clinical sign of the infection and also determine the progression of disease. The purpose of this study was to determine the prevalence of oral soft tissue manifestations and their ...
Davoodi, Poorandokht+4 more
openaire +4 more sources
Real World Lab Data: Patterns of Lymphocyte Counts in Fingolimod Treated Patients
Objective:Fingolimod is approved for the treatment of highly active relapsing remitting multiple sclerosis (MS) patients and acts by its unique mechanism of action via sphingosine-1-phosphate receptor-modulation.
Maxi Kaufmann+4 more
doaj +1 more source
AIDS patients have increased surfactant protein D but normal mannose binding lectin levels in lung fluid. [PDF]
BACKGROUND: Surfactant protein D (SP-D) and Mannose Binding Lectin (MBL) are collectins that have opsonic and immunoregulatory functions, are found in lung fluid and interact with the human immunodeficiency virus (HIV).
French, Neil+3 more
core +2 more sources
The association of CD4 lymphocyte count with drug hypersensitivity reaction to highly active antiretroviral therapy, trimethoprim sulfamethoxazole, and antitubercular agents in human immunodeficiency virus patients. [PDF]
Tarranza JLS, Ang MCD.
europepmc +1 more source
An investigation of the breadth of neutralising antibody response in cats naturally infected with feline immunodeficiency virus [PDF]
Neutralising antibodies (NAbs) are believed to comprise an essential component of the protective immune response induced by vaccines against FIV and HIV infections.
Beczkowski, Pawel+5 more
core +2 more sources
Introduction Different parameters have been established to direct the treatment of patients with human immunodeficiency virus (HIV) infection, such as CD4+ lymphocyte values, and it is of clinical interest to have methodologies that accurately predict ...
Signed Esperanza Prieto Bohorquez+9 more
doaj +1 more source
Modeling the Causal Effect of Treatment Initiation Time on Survival: Application to HIV/TB Co-infection [PDF]
The timing of antiretroviral therapy (ART) initiation for HIV and tuberculosis (TB) co-infected patients needs to be considered carefully. CD4 cell count can be used to guide decision making about when to initiate ART. Evidence from recent randomized trials and observational studies generally supports early initiation but does not provide information ...
arxiv