A simple, inexpensive alternative to CD4 counts would facilitate the management of asymptomatic and early symptomatic patients with HIV infection. In this report, a high correlation was found between CD4 counts and total lymphocyte counts calculated from complete blood counts in a cohort of ambulatory HIV-infected patients.
Arthur M. Fournier, Jay M. Sosenko
openaire +4 more sources
CD4 and total lymphocyte counts as predictors of HIV disease progression [PDF]
CD4+ T-lymphocyte (CD4) counts are a standard laboratory marker of disease progression in HIV infection, but expense precludes their use in large parts of the world. Total lymphocyte counts (TLC), in contrast, are widely available. We compared CD4 and TLC counts as predictors of developing AIDS or death in 831 HIV-positive out-patients (582 males and ...
Post, Frank, Wood, R, Maartens, G
openaire +5 more sources
Early Interferon-γ Production in Human Lymphocyte Subsets in Response to Nontyphoidal Salmonella Demonstrates Inherent Capacity in Innate Cells [PDF]
Background Nontyphoidal Salmonellae frequently cause life-threatening bacteremia in sub-Saharan Africa. Young children and HIV-infected adults are particularly susceptible.
Anna E. Seeley+5 more
core +22 more sources
Absolute lymphocyte count as a marker for Cd4 T-lymphocyte count: criterion for initiating antiretroviral therapy in HIV infected Nigerians [PDF]
Few laboratories in resource-constrained countries can afford to perform laboratory-monitoring tests required for the implementation of HIV therapy. In this case control study, we have investigated the relevance of absolute lymphocyte count as a surrogate marker for CD4 lymphocyte count as a criterion for initiating HAARTin HIV-infected Nigerians.A ...
Emmanuel K. Uko+2 more
openaire +7 more sources
Evaluating total lymphocyte counts as a substitute for CD4 counts in the follow up of AIDS patients [PDF]
This study evaluated total lymphocyte count (TLC) as a substitute marker for CD4+ cell counts to identify patients who need prophylaxis against opportunistic infection (CD4 < 200 cells/mm(3)) and patients with CD4 < 350 cells/mm(3) (Brazilian threshold value of CD4 count to define AIDS).
Angelo, Ana Luiza Dias+6 more
openaire +8 more sources
Use of Total Lymphocyte Count to Predict Absolute CD4 Count in HIV-Seropositive Cases [PDF]
We conducted an observational study to assess the use of total lymphocyte counts (TLC) alone and along with hemoglobin (Hb) as a predictor of CD4 count. A total of 103 antiretroviral therapy (ART)-naive HIV-1-infected patients were enrolled and divided in 2 groups (with CD4 count <200 cells/mm3 and CD4 count ≥200 cells/mm3).
Tejinder Singh+3 more
openaire +4 more sources
Factors associated with CD4 lymphocyte counts in HIV-negative Senegalese individuals [PDF]
Summary CD4+ lymphocytes are a primary target of the human immunodeficiency virus (HIV), and CD4 counts are one of the factors used to measure disease progression in HIV-positive individuals. CD4 counts vary in uninfected individuals and across populations due to a variety of demographic, environmental, immunological and genetic factors ...
Habibatou D. Agne+8 more
openaire +5 more sources
CD4 lymphocyte count: A barometer for HIV/AIDS management
It is probably not a news to say that HIV/AIDS is yet to have a cure and that the dreaded virus can be managed effectively with highly active antiretroviral therapy (HAART). What is however new is the fact that the point of initiating the management regimen in Africa may likely be different from others elsewhere in the globe if your article recently ...
Nassar A. Sulaiman
openaire +5 more sources
Association of T lymphocytes level and clinical severity in patients of COVID-19 in Shenzhen China
To explore the correlation between T lymphocytes and clinical severity in patients of COVID-19. A total of 183 COVID-19 patients were recruited in Shenzhen Third People’s Hospital from January 11 to February 16, 2020.
Wu Qiang+6 more
doaj +1 more source
Predictors of change in CD4 lymphocyte count and weight among HIV infected patients on anti-retroviral treatment in Ethiopia: a retrospective longitudinal study. [PDF]
Antiretroviral treatment (ART) has been introduced in Ethiopia a decade ago and continues to be scaled up. However, there is dearth of literature on the impact of ART on changes in CD4 lymphocyte count and weight among patients on treatment.To determine ...
Ayalu A Reda+4 more
doaj +1 more source