Results 91 to 100 of about 10,623 (204)
SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression
JCI InsightOsteosarcoma (OS) is the most common malignant bone tumor, characterized by a high propensity for metastasis. Recent studies have highlighted the role of alternative splicing in cancer metastasis, although the precise mechanisms underlying aberrant splicing in OS invasion and metastasis remain unclear.
Wenyue Li +11 more
openaire +2 more sources
The effect of splenectomy on complement regulatory proteins in erythrocytes in β-thalassemia major
Archives of Medical Science, 2018 Introduction Hemolysis due to ineffective erythropoiesis is a serious problem β-thalassemia major (β-TM) patients. The role of complement system in the etiopathogenesis of hemolysis observed in β-TM were released.
Ayşegül Uğur Kurtoğllu +3 more
doaj +1 more source
, 2016 Many enveloped RNA viruses recruit host cell proteins during assembly as a mechanism to limit antiviral effects of complement. Using viruses which incorporated CD46 alone, CD55 alone or both CD46 and CD55, we addressed the role of these two host cell ...
Parks, Griffith D. +2 more
core +1 more source
, 2007 CD55 is a key regulator of complement activation, expressed on most tissues and cells in man and other mammals. In the rat, alternative splicing in the gene encoding CD55 yields GPI-anchored (GPI-CD55) and transmembrane (TM-CD55) forms.
Mizuno, Masashi +8 more
core +1 more source
Hematology, Transfusion and Cell TherapyObjetivo: : Descrever o perfil clínico,tratamento e evolução de pacientes com Anemia Aplástica Adquirida (AA) ou Síndrome Mielodisplásica (SMD) associadas à presença de clone de hemoglobinúria paroxística noturna (HPN).
C Berti, MEA Melo, MP Garanito
doaj +1 more source
, 2011 Atherosclerosis, the leading cause of death in the Western world, is driven by chronic inflammation within the artery wall. Elements of the complement cascade are implicated in the pathogenesis, because complement proteins and their activation products ...
Morgan, Bryan Paul +20 more
core +1 more source
Modulation of IL-10 production by CD3/CD55 induced Type 1 regulatory (Tr1) T-cells [PDF]
, 2019 A healthy immune system is maintained in a state of balance between pro-inflammatory and anti-inflammatory cells. The paradigm for T-cell activation requires CD80/86:CD28 engagement resulting in differentiation of CD4+ T-helper cells.
Musarrat, Tajkia
core
Expression of the EGF-TM7 receptor CD97 and its ligand CD55 (DAF) in multiple sclerosis
, 2002 CD97 is a recently identified seven-span transmembrane (7-TM) protein that is expressed by leukocytes early after activation. CD97 binds to its cellular ligand CD55 (decay accelerating factor), which protects several cell types from complement-mediated ...
de Vos, Alex F. +21 more
core +1 more source
GPI锚定蛋白抗体CD55、CD59及RET在贫血诊断中的意义探讨
Zhongguo shiyan zhenduanxue, 2009 目的检测几类贫血患者外周血中红细胞和中性粒细胞膜上糖化磷脂酰肌醇（GPI）连接的补体调节蛋白CD55和CD59表达情况,综合分析各类贫血中网织红细胞（RET）的变化特点,探讨他们在贫血中的诊断价值。方法荧光标记的CD55、CD59单克隆抗体,用流式细胞技术及亚甲蓝活体染色检测,30例正常人、25例缺铁性贫血（IDA）、26例巨幼细胞性贫血（MA）2、7例自身免疫溶血性贫血（AHA）,27例再生障碍性贫血、21例再生障碍性贫血-阵发性睡眠性血红蛋白尿症（AA-PNH）3、0例阵发性睡眠性血红蛋白尿症 ...
钟琼, 马丽
doaj