Results 31 to 40 of about 13,567 (213)
Function of complement regulatory proteins in immunity of reproduction: a review
Czech Journal of Animal Science, 2005 Humoral immunity has an important role during the maturation and development of the functional properties of spermatozoa. Spermatozoa may be exposed to antisperm antibodies in semen and in cervical, ovarian follicular and fallopian fluid.
J. Valentovičová +2 more
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Gecko CD59 is implicated in proximodistal identity during tail regeneration. [PDF]
PLoS ONE, 2011 Several adult reptiles, such as Gekko japonicus, have the ability to precisely re-create a missing tail after amputation. To ascertain the associated acquisition of positional information from blastemal cells and the underlying molecular mechanism of ...
Yongjun Wang +12 more
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Autoimmunity Highlights, 2020 Background CD59 deficiency is a congenital mutation disorder in complement pathway which can present with various manifestations. Case presentation Herein, we presented an adolescent 16-years-old girl with recurrent attacks of Guillain-Barre in early ...
V. Javadi Parvaneh +6 more
semanticscholar +1 more source
Complement Terminal Pathway Activation is Associated with Organ Failure in Sepsis Patients
Journal of Inflammation Research, 2022 Fatima M Ahmad,1,2 Maysaa’ A Al-Binni,2 Amjad Bani Hani,3 Mahmoud Abu Abeeleh,3 Anas HA Abu-Humaidan1 1Department of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman, Jordan; 2Department of the Clinical ...
Ahmad FM +4 more
doaj
Defining the CD59-C9 Binding Interaction [PDF]
Journal of Biological Chemistry, 2006 CD59 is a membrane glycoprotein that regulates formation of the cytolytic membrane attack complex (MAC or C5b-9) on host cell membranes. It functions by binding to C8 (alpha chain) and C9 after their structural rearrangement during MAC assembly. Previous studies indicated that the CD59 binding site in C9 was located within a 25-residue disulfide-bonded
Yuxiang, Huang +4 more
openaire +2 more sources
Cell Reports, 2013 Pore-forming proteins containing the structurally conserved membrane attack complex/perforin fold play an important role in immunity and host-pathogen interactions.
Steven Johnson +4 more
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An update on the CD59 blood group system [PDF]
Immunohematology, 2019 Abstract This update of the CD59 blood group system (Weinstock C, Anliker M, von Zabern I. CD59: a long-known complement inhibitor has advanced to a blood group system. Immunohematology 2015;31:145–51) increases the number of reported patients with CD59 deficiency from 10 to 14.
Weinstock, C. +2 more
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Cell Death and Disease, 2019 Tumor-associated macrophages (TAMs) are versatile immune cells that promote a variety of malignant behaviors of pancreatic cancer. CD59 is a GPI-anchored membrane protein that prevents complement activation by inhibiting the formation of the membrane ...
Ronghua Zhang +6 more
semanticscholar +1 more source
Six monoclonal antibodies to the CD59 antigen [PDF]
Immunohematology, 1993 Abstract CD59 defines an N -glycosylated glycoprotein expressed on various hemopoietic cells. It is anchored to the cell membrane by a glycosylphosphatidylinositol linkage and restricts the action of homologous complement.
J A, Bryant, A, Fletcher, F F, Yuan
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Relating GPI-Anchored Ly6 Proteins uPAR and CD59 to Viral Infection
Viruses, 2019 The Ly6 (lymphocyte antigen-6)/uPAR (urokinase-type plasminogen activator receptor) superfamily protein is a group of molecules that share limited sequence homology but conserved three-fingered structures.
Jingyou Yu, Vaibhav Murthy, Shan-Lu Liu
semanticscholar +1 more source