Results 21 to 30 of about 13,567 (213)
Autoimmunity, 2017 Pemphigus foliaceus (PF) is an autoimmune disease, endemic in Brazilian rural areas, characterized by acantholysis and accompanied by complement activation, with generalized or localized distribution of painful epidermal blisters.
Amanda Salviano-Silva +2 more
doaj +2 more sources
International Journal of General Medicine, 2019 Dalia Mahmoud Eldewi,1 Alshaymaa M Alhabibi,1 Hanaa Mohammed Eid El Sayed,2 Sammar Ahmed Kasim Mahmoud,2 Sanaa Mohammed El Sadek,3 Rasha Mahmoud Gouda,3 Mohammed Abd El Malik Hassan,4 Amal H Ibrahim,2 Naglaa F Abd El Haliem5 1Clinical Pathology ...
Eldewi DM +8 more
doaj +2 more sources
Cancers, 2022 Simple Summary It is well recognized that EVs carry many membrane proteins on their surface that can transduce signals to recipient cells and serve as biomarkers/target proteins for the diagnosis /treatment of diseases.
Srinivas Dash +9 more
semanticscholar +1 more source
Cells, 2022 Daratumumab (DARA) has improved the outcome of treatment of multiple myeloma (MM). DARA acts via complement-dependent and -independent mechanisms.
K. Brennan +5 more
semanticscholar +1 more source
CD59-Regulated Ras Compartmentalization Orchestrates Antitumor T-cell Immunity
Cancer immunology research, 2022 The subcellular compartmentalization of Ras is regulated by interacting with intracellular CD59. CD59 deficiency results in reduced trafficking of Ras to the plasma membrane in T cells, thus inducing increased T-cell signal transduction and antitumor ...
Luying Li +12 more
semanticscholar +1 more source
CD59 Expression in Skeletal Muscles and Its Role in Myasthenia Gravis
Neurology: Neuroimmunology & Neuroinflammation, 2022 Background and Objectives Complement regulatory proteins at the neuromuscular junction (NMJ) could offer protection against complement-mediated damage in myasthenia gravis (MG).
Kazuo Iwasa +4 more
semanticscholar +1 more source
CD59 (CD59 molecule, complement regulatory protein) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013 Review on CD59 (CD59 molecule, complement regulatory protein), with data on DNA, on the protein encoded, and where the gene is implicated.
Donev, RM, Kolev, MV
openaire +2 more sources
Paroxysmal Nocturnal Haemoglobinuria Masquerading as Malaria: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2015 Paroxysmal Nocturnal Haemoglobinuria (PNH) is a rare type of acquired Haemolytic anaemia that is described as a triad of acquired intravascular Haemolysis, venous thrombosis and anaemia with pancytopenia sometimes due to bone marrow failure. However the
Archana Dambal +4 more
doaj +1 more source
Mapping the Active Site of CD59 [PDF]
The Journal of Experimental Medicine, 1997 CD59 is a widely distributed membrane-bound inhibitor of the cytolytic membrane attack complex (MAC) of complement. This small (77 amino acid) glycoprotein is a member of the Ly6 superfamily of proteins and is important in protecting host cells from the lytic and proinflammatory activity of the MAC.
Yu, Jinghua +5 more
openaire +4 more sources
Journal of Neuroinflammation, 2023 Background Homozygous CD59-deficient patients manifest with recurrent peripheral neuropathy resembling Guillain-Barré syndrome (GBS), hemolytic anemia and recurrent strokes.
Netanel Karbian +9 more
doaj +1 more source