Results 11 to 20 of about 7,063 (170)
Dietary CoQ10 Ameliorates Age-Related Megakaryocyte Dysfunction via COPS3-Mediated Activation of Autophagy. [PDF]
Aging CellDietary CoQ10 improves megakaryocyte maturation and polyploidization and reduces platelet hyperreactivity in naturally aged mice, while experiments in senescent Meg‐01 cells demonstrate enhanced autophagic flux and identify COPS3 as a contributing, but not, mediator.
Xu Y +9 more
europepmc +2 more sources
Advanced Science, 2023 The knowledge of osteoarthritis (OA) has nowadays been extended from a focalized cartilage disorder to a multifactorial disease. Although recent investigations have reported that infrapatellar fat pad (IPFP) can trigger inflammation in the knee joint ...
Bingyang Dai +19 more
doaj +1 more source
BMC Gastroenterology, 2022 Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest gastrointestinal cancers with a 5-year survival rate of less than 10%. Biomarkers for early PDAC detection are useful in treating patients with PDAC.
Haruki Odaka +4 more
doaj +1 more source
Age- and Pregnancy-Associated DNA Methylation Changes in Mammary Epithelial Cells
Stem Cell Reports, 2015 Postnatal mammary gland development and differentiation occur during puberty and pregnancy. To explore the role of DNA methylation in these processes, we determined the genome-wide DNA methylation and gene expression profiles of CD24+CD61+CD29hi, CD24 ...
Sung Jin Huh +14 more
doaj +1 more source
Veterinary Immunology and Immunopathology, 1996 After analysis of flowcytometry data on bovine and ovine cells and immunoprecipitation studies, a cluster of seven MAbs-CAPP2 (3W-232), IL-Al64 (M430), IL-Al66 (3W-226), IVA30 (3W-069), IVA31 (3W-468), IVA38 (3W-349) and IVA125 (3W528)-was shown to detect bovine and ovine CD41/Cd61 (also known as allS Mateo et al., 1996a). MAb Co-35E4, not submitted to
Mateo, A. +6 more
openaire +3 more sources
Liquid Biopsy in Organ Damage: small extracellular vesicle chip-based assessment of polytrauma
Frontiers in Immunology, 2023 BackgroundDespite major advances in medicine, blood-borne biomarkers are urgently needed to support decision-making, including polytrauma. Here, we assessed serum-derived extracellular vesicles (EVs) as potential markers of decision-making in polytrauma ...
Bingduo Wang +25 more
doaj +1 more source
Indian Journal of Rheumatology, 2018 Introduction: Microparticles (MPs) are submicron sized heterogeneous membrane-bound vesicles released from cells undergoing cell activation or apoptosis. Elevated platelet-derived MPs (PMPs) are reported in rheumatic diseases.
Benita N R Michael +3 more
doaj +1 more source
Platelet Membrane Proteins as Pain Biomarkers in Patients with Severe Dementia
Biomedicines, 2023 Pain is one of the most frequent health problems, and its evaluation and therapeutic approach largely depend on patient self-report. When it is not possible to obtain a self-report, the therapeutic decision becomes more difficult and limited.
Hugo Ribeiro +7 more
doaj +1 more source
Circulating Small Extracellular Vesicles Reflect the Severity of Myocardial Damage in STEMI Patients
Biomolecules, 2023 Circulating small extracellular vesicles (sEVs) contribute to inflammation, coagulation and vascular injury, and have great potential as diagnostic markers of disease.
Marta Zarà +24 more
doaj +1 more source
Cryoglobulins Interfere with Platelet Counts by Optical and Impedance Methods but not with the CD61 Immunoplatelet Count [PDF]
Clinical Chemistry, 2001 Automated complete blood counts (CBCs) use supplementary warnings (flags) to provide alerts for the existence of hematologic abnormalities (1). We observed on several occasions platelet-count interference by cryoglobulins, where the impedance and optical results were in error to a similar extent and did not trigger a delta alert. Platelets usually are
von Ahsen, Nicolas +4 more
openaire +3 more sources