Results 51 to 60 of about 7,063 (170)

Defective expression of scavenger receptors in celiac disease mucosa. [PDF]

PLoS ONE, 2014
Celiac disease (CD) is a gluten sensitive enteropathy characterized by a marked infiltration of the mucosa with immune cells, over-production of inflammatory cytokines and epithelial cell damage.
Maria Laura Cupi, Massimiliano Sarra, Daniela De Nitto, Eleonora Franzè, Irene Marafini, Ivan Monteleone, Giovanna Del Vecchio Blanco, Omero Alessandro Paoluzi, Davide Di Fusco, Paolo Gentileschi, Angela Ortenzi, Alfredo Colantoni, Francesco Pallone, Giovanni Monteleone   +13 more
doaj   +1 more source

Mechanisms of Thrombocytosis in Iron‐Deficiency Anemia

European Journal of Haematology, Volume 117, Issue 4, Page 728-738, October 2026.
ABSTRACT Iron‐deficiency anemia is frequently accompanied by reactive thrombocytosis, yet the mechanisms underlying this association remain incompletely understood. Beyond impaired erythropoiesis, iron availability has emerged as an active regulator of hematopoietic lineage decisions.
João Vitor Facco, Diane S. Krause, Sara T. Olalla Saad   +2 more
wiley   +1 more source

Downscaling to small‐volume storage bags supports platelet quality and efficient use of cold‐stored platelets for preclinical studies

Transfusion, Volume 66, Issue 10, Page 1952-1962, October 2026.
Abstract Background To maximize the utilization of cold‐stored platelets (CSPs) in preclinical research, the use of small‐volume storage bags (mini‐bags) or tubes would allow multiple treatment groups to be investigated from a single component. It is necessary to determine the effect of using downscaled storage formats on CSP quality and function ...
Janhavi Mahajan, Matthew P. Padula, Denese C. Marks, Lacey Johnson   +3 more
wiley   +1 more source

Host‐to‐Pathogen Transfer of Neutrophil Components via Extracellular Vesicles Shields Candida albicans From Immune Attack in Human Blood

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Neutrophils release extracellular vesicles (EVs) in response to Candida albicans, and these EVs bind to the fungus in a complement‐dependent manner while carrying neutrophil surface markers and antimicrobial proteins. Despite this cargo, EV coating does not inhibit fungal growth but markedly reduces neutrophil phagocytic uptake in purified‐cell assays ...
Jennifer J. Patitz, Natalie E. Nieuwenhuizen, Anastasia Solomatina, Yann Bachelot, Thomas Krüger, Carl‐Magnus Svensson, Stephanie Hoeppener, Ann‐Kathrin Zimmermann, Matthew G. Blango, Ronny Martin, Olaf Kniemeyer, Theresa Lange, Axel A. Brakhage, Marc Thilo Figge, Oliver Kurzai, Kerstin Hünniger‐Ast   +15 more
wiley   +1 more source

Transient abnormal myelopoiesis: A case series and review of the literature

Pediatric Hematology Oncology Journal, 2017
Transient abnormal myelopoiesis (TAM) is a rare and unique disorder affecting Down syndrome (DS) newborns. This case series presents 5 cases of Down syndrome with TAM diagnosed during 2007–2015 with detailed analysis of immunophenotypic data of each case.
Vandana Baloda, Papagudi G. Subramanian, Yajamanam Badrinath, Ashok Kumar, Pratibha S. Kadam Amare, Shripad D. Banavali, Brijesh Arora, Sumeet Gujral   +7 more
doaj   +1 more source

A Beginner's Guide to Study the Role of Extracellular Vesicles in Coagulation

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT This guide provides an overview of information that is needed to understand and study the coagulant functions of extracellular vesicles (EVs) in human body fluids. Although EV research has expanded rapidly, the physiological functions of EVs remain incompletely understood, and coagulation is one of the first biological functions that was ...
Rienk Nieuwland, Jillian W. P. Bracht, Joost C. M. Meijers, Johannes Thaler   +3 more
wiley   +1 more source

A Rare Case of Cutaneous Extramedullary Hematopoiesis in Chronic Myeloid Leukemia

Journal of Cutaneous Pathology, Volume 53, Issue 9, Page 767-771, September 2026.
ABSTRACT Cutaneous extramedullary hematopoiesis (CEH) is a rare manifestation of extramedullary hematopoiesis (EMH), a process typically associated with fetal development or myeloproliferative neoplasms. EMH most commonly involves the spleen, liver, and lymph nodes, with CEH being exceedingly rare in chronic myeloid leukemia (CML).
Bennett Christie‐Nguyen, Hanadi El Achi, Levani Iashvili, Amer Wahed, Brenda Mai, Jacob Armstrong   +5 more
wiley   +1 more source

Hepatosplenomegaly Associated with Transient Abnormal Myelopoiesis in Down Syndrome: An Autopsy Case of a Stillborn Fetus

Case Reports in Oncology, 2015
A 38-year-old primiparous mother (gravida 1, para 0) at 27 weeks and 6 days' gestation reported that fetal movements had been absent for 6 days. All serological markers for infection were negative.
Michiko Yuki, Yuko Emoto, Yuichi Kinoshita, Katsuhiko Yoshizawa, Takashi Yuri, Airo Tsubura   +5 more
doaj   +1 more source

Development of an ex vivo xenogeneic bone environment producing human platelet-like cells.

PLoS ONE, 2020
The efficiency of in vitro platelet production is considerably low compared with physiological activity due to the lack of pivotal factors that are essential in vivo.
Shingo Fujiyama, Nobuyasu Hori, Toshiyuki Sato, Shin Enosawa, Mitsuru Murata, Eiji Kobayashi   +5 more
doaj   +1 more source

The Role of TLR-2 in Lethal COVID-19 Disease Involving Medullary and Resident Lung Megakaryocyte Up-Regulation in the Microthrombosis Mechanism

Cells
Patients with COVID-19 have coagulation and platelet disorders, with platelet alterations and thrombocytopenia representing negative prognostic parameters associated with severe forms of the disease and increased lethality. Methods: The aim of this study
Giuseppe Pannone, Maria Carmela Pedicillo, Ilenia Sara De Stefano, Francesco Angelillis, Raffaele Barile, Chiara Pannone, Giuliana Villani, Francesco Miele, Maurizio Municinò, Andrea Ronchi, Gaetano Serviddio, Federica Zito Marino, Renato Franco, Tommaso Colangelo, Rosanna Zamparese   +14 more
doaj   +1 more source