Results 101 to 110 of about 120,442 (308)

CD68 immunostaining in rats implanted with synthetic mesh.

, 2012
A. PA after 7 days and B. after 90 days implantation (- - - line around mesh filament). Brown staining indicates CD68+ macrophages. C. Percentage CD68 positive area within 50 µm radius of central mesh filament bundle. Data are mean ± SEM of n = 6 animals/
Tommy Supit (118643), Jerome A. Werkmeister (118659), Jacinta F. White (118640), John A. M. Ramshaw (118646), Sharon L. Edwards (118633), Camden Lo (118651), Daniela Ulrich (118627), Anna Rosamilia (118655), Caroline E. Gargett (118663)   +8 more
core   +1 more source

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

Advanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang, Chengfei Jiang, April W. Mao, Qi Sun, Yijun Lu, Jingjing Wei, Jamie L. Inman, Susan E. Celniker, Antoine M. Snijders, David W. Threadgill, Allan Balmain, Bo Hang, Hang Chang, Lei Wang, Jian‐Hua Mao   +14 more
wiley   +1 more source

Clinicopathological correlation of tumor-associated macrophages in Ewing sarcoma

Biomedical Papers, 2018
Aims: Tumor-associated macrophages (TAMs) are known markers playing complex roles in tumorigenesis. However, the function of TAMs in a variety of malignancies is not yet fully understood. The aim of this pilot study was to quantify the density of TAMs in
Marek Handl, Marketa Hermanova, Sylva Hotarkova, Jiri Jarkovsky, Peter Mudry, Tetiana Shatokhina, Marcela Vesela, Jaroslav Sterba, Iva Zambo   +8 more
doaj   +1 more source

[Investigation of CD68 positive monocytes/macrophage(CD68+ Mo/M phi) in urine and infiltrated tissue of various kidney diseases in children].

Nihon Jinzo Gakkai shi, 2002
In order to investigate the participation of monocytes/macrophages(Mo/M phi) in the progression of various kidney diseases of children, Mo/M phi in urine and that infiltrating renal tissue were both measured as the number of CD68 positive Mo/M phi (CD68+ Mo/M phi), using anti-CD68 antibody.
SAITOH, Akira, IKOMA, Masaaki, KAMIYAMA, Chieko, DOT, Keiji, KOITABASHI, Yasushi   +4 more
openaire   +2 more sources

Pie charts showing the kind of macrophage polarization in pediatric classical Hodgkin lymphoma, considering CD68 (A) or CD163 (C) as macrophage markers.

, 2015
Box-plot graphs show the numerical distribution of CD68+pSTAT1+, CD68+pSTAT1-, CD68+CMAF+ and CD68+CMAF- cells/mm2 (B), as well as CD163+pSTAT1+, CD163+pSTAT1-, CD163+CMAF+ and CD163+CMAF- cells/mm2 (D).
Priscilla Segges (739734), Gerald Niedobitek (26442), Mário H. M. Barros (132399), Rocio Hassan (132411), Gabriela Vera-Lozada (739735)   +4 more
core   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

CD68 -immune reactive microglia in the brain sections of mice (magnifications: 10X, 40X).

, 2019
The photomicrograph illustrates the following groups: (a, b) normal mice showing sparse weakly CD68 positive immune stained cells, (c, d) control mice showing significant increase of CD68 immune stained microglia surrounding amyloid plaques, (e, f ...
Farghaly A. Omar (6920111), Mohammed N. A. Khalil (6920102), Salma A. El-Marasy (6920108), Mouchira A. Choucry (6920105), Azza Hassan (678637), Amira S. El Senousy (672322), Sally A. El Awdan (710176)   +6 more
core   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Immunohistochemical Evaluation of CD68, β-catenin, α-SMA and Ki67 Expression in Kupffer and Parenchymal Stellate Cells Associated With Bovine Liver Lesions Leading to Fibrosis [PDF]

Archives of Razi Institute
Introduction: Liver fibrosis is a disorder resulting from numerous diseases that threaten animal life. Materials and Methods: Over two years (2021-2023), a total of 1,525 bovine livers were inspected, and common liver diseases leading to fibrosis ...
Pardis Khodagholizadeh, Amir Amniattalab
doaj   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source