Results 81 to 90 of about 111,342 (306)

CD68 is expressed by macrophages and osteoclasts.

, 2013
(A) CD68 and β-actin expression in mouse bone marrow suspension cells treated with 44 ng/mL M-CSF +/− 100 ng/mL RANKL for indicated days (d). M-CSF increases expression of CD68 in a time dependant manner, and RANKL ligand induces an accelerated gel ...
Robert A. Kesterson (342895), Xu Feng (342896), Jason W. Ashley (342892), Haibo Zhao (198087), Zhenqi Shi (342893), Xingsheng Li (342894)   +5 more
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Specific clinical and immune features of CD68 in glioma via 1,024 samples

, 2018
Le Wang,1,2,* Chaoqi Zhang,1,3,* Zhen Zhang,1 Bing Han,4 Zhibo Shen,1 Lifeng Li,1,3 Shasha Liu,1 Xuan Zhao,1 Fanglei Ye,2 Yi Zhang1,3,5 1Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; 2Department
Han B, Shen Z, Zhang Z, Zhang Y, Liu S, Ye F, Zhang C, Li L, Wang L, Zhao X   +9 more
core  

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Pleomorphic rhabdomyosarcoma: a case study

Vestnik Dermatologii i Venerologii, 2017
Pleomorphic rhabdomyosarcoma of the skin is a fast progressing tumor with high risk of development of lymphogenous and hematogenous metastasis, low survival rates and complex diagnostics. this clinical case describes the application of typing tumor cells
A. V. Kozlova, V. M. Kazakov, L. N. Kokh, T. G. Ruksha   +3 more
doaj   +1 more source

Immunohistochemistry stain of CD68 in the lung.

, 2013
(A) Representative lung sections taken from the control mice and the 29.5 kg, 103.5 mg/kg and 177.5 administered mice at 400× magnification. Positive signals of CD68 expression were occasionally observed in suspected granuloma in the lung sections from ...
Zhiwei Sun (153761), Minghua Jin (402267), Yanbo Li (402269), Yang Yu (4292), Yang Li (7082), Junchao Duan (402270), Wen Wang (6570), Zhongjun Du (402268), Yongbo Yu (402271)   +8 more
core   +1 more source

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Advanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao, Ruqiong Wang, Bo An, Lishuang Qi, Zihan Jing, Xingmei Ren, Yang Zhou, Mingjun Xu, Jiaojiao Li, Jie Liu, Liying Wang, Gang Xu, Rou Li, Dexin Jia, Yan Yu   +14 more
wiley   +1 more source

Immunohistochemistry stain of CD68 in the liver.

, 2013
(A) Representative liver sections taken from control mice and 29.5 mg/kg, 103.5 mg/kg and 177.5 mg/kg administered mice at 400× magnification. Hepatic granulomas showed strong positive signals for CD68 in the SNP treated mice. Arrows denote CD68 positive
Zhiwei Sun (153761), Minghua Jin (402267), Yanbo Li (402269), Yang Yu (4292), Yang Li (7082), Junchao Duan (402270), Wen Wang (6570), Zhongjun Du (402268), Yongbo Yu (402271)   +8 more
core   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

The Role of Immunohistochemistry in Reducing the “Atypia of Undetermined Significance (AUS)” Category in Serous Fluid Cytology

Journal of Cytology
Background and Aims:The International Serous Fluid Cytopathology Reporting System aimed to establish standardized protocols to ensure consistency in the reporting of serous fluid cytological specimens.
Enver Yarikkaya, Senay Erdogan-Durmus
doaj   +1 more source