Results 131 to 140 of about 120,442 (308)

Associations between intratumoral CD68-positive and patients' clionicaopathologic characteristics.

, 2015
Associations between intratumoral CD68-positive and patients' clionicaopathologic characteristics.
Ming-Tsan Lin (49458), Min-Liang Kuo (282508), Ming-Hsun Wu (777350), Kuo-Tai Hua (680908), Wei-Jiunn Lee (457880)   +4 more
core   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

P02.21.A PROGNOSTIC ROLE OF CD68 AND CD163 IN GLIOMAS

Neuro-Oncology
Abstract BACKGROUND Tumor-associated macrophages (TAMs) have been demonstrated to play an important role in the growth and progression of multiple types of cancer, including glioblastoma. The aim of this study is to evaluate the distribution of CD68 and CD163 markers for TAMs in glioma samples and to ...
Petrescu, G E D, Dragomir, M P, Brehar, F M, Gorgan, R M   +3 more
openaire   +2 more sources

Increased CD163+cells/CD68+ cells ratio in IBD tissue.

, 2013
A. Representative photomicrographs (100× original magnification) in serial paraffin-embedded sections of surgical samples taken from 1 CTR, 1 patient with UC and 1 patient with CD and stained with CD163 or CD68.
Roberta Caruso (438408), Alfredo Colantoni (438413), Livia Biancone (288349), Daniela De Nitto (438412), Ivan Monteleone (288334), Francesco Pallone (288353), Maria Laura Cupi (438410), Francesca Zorzi (288332), Giovanni Monteleone (288355), Flavio Caprioli (438411), Massimiliano Sarra (288336), Carmine Stolfi (438409), Eleonora Franzè (438407)   +12 more
core   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

Osteoclastogenic Potential of CD68-Expressing Osteoclast Precursor Cells

Osteoclasts, which resorb bone, are essential for skeletal maintenance, but their overactivity contributes to bone fragility and diseases such as osteoporosis and rheumatoid arthritis.
Quinn, Colton Raymond
core   +1 more source

Prevalence of the CD68 positive activated microglial cells/macrophages.

, 2017
Prevalence of the CD68 positive activated microglial cells/macrophages.
Sandra Skuja (3628925), Anete Zieda (3628916), Ojars Teteris (3628922), Kristine Ravina (3628919), Modra Murovska (3628910), Silvija Roga (3628931), Svetlana Chapenko (3628913), Valerija Groma (3628928)   +7 more
core   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Cumulative meta-analysis of the association between CD68+ TAMs and prognosis.

, 2019
(A) Intratumoral CD68+ TAMs and OS; (B) Peritumoral CD68+ TAMs and OS.
Yan Qian (388125), Wei Ding (690), Wenbo Xue (1790827), Yibo Wang (304377), Peng Jiang (16544), Xuezhong Xu (688748), Yulin Tan (1771855)   +6 more
core   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source