Results 71 to 80 of about 35,344 (261)

Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia.

open access: yes, 2007
In most models of blood-stage malaria infection, proinflammatory immune responses are required for control of infection and elimination of parasites.
Couper, Kevin N   +16 more
core   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

open access: yesAdvanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng   +15 more
wiley   +1 more source

Significance and Regulation of CD68 Expression in the Osteoclast

open access: yes, 2011
The mucin-like Lysosome Associated Membrane Protein (LAMP) family member CD68 is a primarily myeloid lineage restricted transmembrane protein that is expressed in macrophages and osteoclasts.
Ashley, Jason Waid
core  

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao   +14 more
wiley   +1 more source

Biological effects of CD68 molecule and matrix metalloproteinase -2 and -9 enzymes in the atherosclerotic process

open access: yes, 2018
Cilj istraživanja: Ateroskleroza predstavlja upalnu, metaboličku, imunološku i degenerativnu bolest, koja u svoj etiopatogenezi ujedinjuje genetske i okolišne čimbenike, dovodeći do narušavanja radne sposobnosti i kvalitete života, a praćena je visokim
Lekić, Andrica
core  

Neural cell adhesion molecule expression on renal interstitial cells

open access: yes, 2007
Background. At early stages of kidney development, the neural cell adhesion molecule (NCAM) is highly expressed on cells of the metanephrogenic mesenchyme. During maturation of the fetal kidney, NCAM gradually disappears.
Markovic-Lipkovski, Jasmina   +7 more
core   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang   +8 more
wiley   +1 more source

Characterizing The Roles Of Il-11 And Cd68 In Breast Cancer Bone Metastasis

open access: yes, 2013
The molecular mechanisms regulating the preferential metastasis of breast cancer to bone have not been fully elucidated, but it is hypothesized that local conditions in the bone create an environment conducive to colonization by breast cancer cells and ...
McCoy, Erin Mills
core  

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

open access: yesAdvanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia   +4 more
wiley   +1 more source

Cellular localization of hepatic RANK in PBC.

open access: yes, 2016
RANK (red) expression in liver was analyzed by confocal scanning microscopy to identify cell types expressing the molecule. Anti-anti-CD11c, anti-CD56, and anti-CD68 are shown in green. Co-localization staining represented by yellow (green+ red).
Cristina Sobacchi (3122352)   +35 more
core   +1 more source

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