Results 1 to 10 of about 291,218 (316)

Acute SARS-CoV-2 pneumonitis with cytotoxic CD8 positive T-lymphocytes: Case report and review of the literature. [PDF]

Pathol Res Pract, 2021
As of October 2020, there are over 40 million confirmed cases, and more than 1 million confirmed deaths of Covid-19 worldwide. The main cause of death in hospitalized patients is a respiratory failure due to acute respiratory distress syndrome. It has been suggested that the very intense immune response induces diffuse alveolar damage that far exceeds ...
Puzyrenko A, Felix JC, Sun Y, Rui H, Sheinin Y.   +4 more
europepmc   +5 more sources

High level of EZH2 expression is linked to high density of CD8-positive T-lymphocytes and an aggressive phenotype in renal cell carcinoma. [PDF]

World J Urol, 2021
Abstract Purpose Enhancer of zeste homolog 2 (EZH2), the catalytic part of the Polycomb repressive complex 2 (PRC2), has a prognostic role in renal cell carcinoma (RCC) and was recently shown to modulate the immune response by reducing tumor cell immunogenicity.
Eichenauer T, Simmendinger L, Fraune C, Mandelkow T, Blessin NC, Kluth M, Hube-Magg C, Möller K, Clauditz T, Weidemann S, Dahlem R, Fisch M, Riechardt S, Simon R, Sauter G, Büscheck F, Rink M.   +16 more
europepmc   +6 more sources

CD8 Positive T Lymphocyte Infiltration of Liver Metastases of Uveal Melanoma: A Case Report [PDF]

Frontiers in Oncology, 2021
A 78-year-old Japanese man was referred for examination of multiple small nodules on his liver detected by magnetic resonance imaging (MRI). These small nodules were hyperintense on T1-weighted MRI, and were in hepatobiliary phase on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid enhanced MRI.
Naoki Takahashi, Kazuto Tajiri, Ko Kagoyana, Shinichi Tanaka, Ichiro Yasuda   +4 more
openalex   +4 more sources

Intraepithelial CD8-positive T lymphocytes predict survival for patients with serous stage III ovarian carcinomas: relevance of clonal selection of T lymphocytes [PDF]

British Journal of Cancer, 2009
The aim of this study was to investigate the prognostic effect of tumour-infiltrating lymphocytes (TILs) in serous stage III ovarian carcinoma to determine TIL clonality and to correlate this to Her2/neu expression.Formalin-fixed and paraffin-embedded ovarian carcinomas were examined for CD20-, CD3-, CD4- and CD8-positive lymphocytes (n=100), and for ...
M. Stumpf, Annette Hasenburg, M-O Riener, Uta Jütting, Cheng Wang, Yijun Shen, Marzenna Orlowska‐Volk, Paul Fisch, Zhishan Wang, G. Gitsch, Martin Werner, Silke Laßmann   +11 more
openalex   +4 more sources

Cytotoxic CD8-positive T-lymphocyte infiltration in the lungs as a histological pattern of SARS-CoV-2 pneumonitis [PDF]

Pathology, 2021
Despite millions of PCR confirmed cases of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, the long-term pathophysiological changes induced by this infection in the lungs and their relationship with possible immune triggers remain incompletely understood. Acute respiratory distress syndrome and subsequent respiratory failure are
Andrii Puzyrenko, Juan C. Felix, Nathan A. Ledeboer, Yunguang Sun, Hallgeir Rui, Yuri Sheinin   +5 more
openalex   +3 more sources

Prognostic Value of Tumour Infiltrating T-Lymphocytes (Tils) with Special Preference to CD8 Positive T-Lymphocyte in Muscle Invasive Urothelial Bladder Cancer [PDF]

Egyptian Journal of Hospital Medicine
Background: Bladder cancer (BC) is one of the most prevalent malignant tumours in Egypt. Several studies reported talented results  using combined tri-modality therapy in muscle invasive bladder cancer (MIBC) with transurethral resection, radiation therapy and  platinum-based systemic chemotherapy.
Hamza, Mona Atta, Khatar, Sherry Mohamed, El-Beshibishi, Wafaa Nagah, Abd-Allah, Eman Awad, Fouda, Mona Mohamed   +4 more
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Effector functions of CD8-positive guinea pig T lymphocytes

Cellular Immunology, 2003
The response of guinea pig T lymphocytes to different stimuli was analysed with focus on the functions of CD8-positive T cells, which so far had been poorly defined in this animal model. For identification and purification of guinea pig cytotoxic T lymphocytes, three monoclonal antibodies, directed against the CD8 differentiation antigen were ...
Hubert Schäfer, Rik J. Scheper, Bettina Borsorf, Reinhard Bürger   +3 more
openalex   +4 more sources

CD4+CD8+ Double-Positive T-Lymphocytes: Pitfalls

Turkish Journal of Hematology, 2020
İrfan Yavaşoğlu
doaj   +2 more sources

Abstract 1084: The role of tumor-associated neutrophils (TAN) and CD8 positive T lymphocyte in the progression of hepatocellular carcinoma (HCC)

Cancer Research, 2019
Abstract [Background]Neutrophils are known as immune cells involved in biological defense against foreign substances. On the other hand, in the tumor microenvironment, it is said that neutrophils affect on tumor progression as a tumor-associated neutrophil (TAN). Although, TAN and other immune cells in the progression of HCC is unclear.
Toshihiko Yusa, Hirohisa Okabe, Yo‐ichi Yamashita, Takanobu Yamao, Naoki Umezaki, Tatsunori Miyata, Shigeki Nakagawa, Hiromitsu Hayashi, Katsunori Imai, Akira Chikamoto, Takatoshi Ishiko, Hideo Baba   +11 more
openalex   +2 more sources

Autologous NY-ESO-1-specific CD8-positive T Lymphocytes [PDF]

, 2020
National Cancer Institute
openalex   +2 more sources