Acta Cirúrgica Brasileira, 2007 PURPOSE: To evaluate the effects of glutamine (L-Gln) or whey-protein supplementation on CD4+ and CD8+ lymphocytes in alloxan-induced diabetic rats. METHODS: Thirty-two healthy male Wistar rats were used in the experiment.
Renato Motta Neto +5 more
doaj +1 more source
Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking. [PDF]
PLoS Pathogens, 2009 Zwitterionic capsular polysaccharides (ZPS) of commensal bacteria are characterized by having both positive and negative charged substituents on each repeating unit of a highly repetitive structure that has an alpha-helix configuration.
Janina Mertens +14 more
doaj +1 more source
Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4
Frontiers in Immunology, 2021 Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment.
Tobias Burkard +6 more
doaj +1 more source
The effects of splenic irradiation on lymphocyte subpopulations in chronic B-lymphocytic leukemia [PDF]
, 1988 We describe the effect of splenic irradiation (SI) (0,5–1 Gy weekly) on lymphocyte subpopulations for 7 patients with progressive B chronic B-lymphocytic leukemia (B-CLL).
Aabo +24 more
core +3 more sources
Journal of Neuroinflammation, 2022 Background Interleukin-27 (IL-27) can trigger both pro- and anti-inflammatory responses. This cytokine is elevated in the central nervous system (CNS) of multiple sclerosis (MS) patients, but how it influences neuroinflammatory processes remains unclear.
Florent Lemaître +13 more
doaj +1 more source
JC virus-DNA detection is associated with CD8 fffector accumulation in peripheral blood of patients with multiple sclerosis under natalizumab treatment, independently from JC virus serostatus [PDF]
, 2018 Although natalizumab (anti-α4 integrin) represents an effective therapy for relapsing remitting multiple sclerosis (RRMS), it is associated with an increased risk of developing progressive multifocal leukoencephalopathy (PML), caused by the polyomavirus ...
Anzivino, Elena +16 more
core +3 more sources
Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations
Frontiers in Immunology, 2018 The nucleopore is an essential structure of the eukaryotic cell, regulating passage between the nucleus and cytoplasm. While individual functions of core nucleopore proteins have been identified, the role of other components, such as Nup210, are poorly ...
Annemarie van Nieuwenhuijze +19 more
doaj +1 more source
PLoS ONE, 2022 Background and aimGrowing evidence highlighted the primary role of the immune system in the disease course of triple-negative breast cancer (TNBC). The study aim was to investigate the expression of PD-1 and CD39 on CD4+ and CD8+ cells infiltrating tumor
Asmaa M Zahran +6 more
doaj +1 more source
Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands [PDF]
, 1992 Cytomegalovirus (CMV), similar to other members of the Herpesviridae family, can establish both persistent and latent infections. Each of the CMVs that are found in many animal species replicates in the salivary gland, and oral secretion represents a ...
Jonjic, Stipan +4 more
core +2 more sources
Comparison of T and NK lymphocyte subsets between human endometrial tissue and peripheral blood
Central European Journal of Immunology, 2019 Immune profiles in endometrium may be changed in patients with IVF failure and its possible correlations with immune parameters in peripheral blood are important for the diagnostic approach.
Viktor Chernyshov +3 more
doaj +1 more source