Results 231 to 240 of about 93,479 (280)

Investigation of the CTLA-4-CD28 Axis in Oral Squamous Cell Carcinoma. [PDF]

J Clin Med
Feldmeier F, Weber M, Pacelli F, Vogl C, Glajzer J, Trumet L, Buchbender M, Geppert C, Kesting M, Ries J.   +9 more
europepmc   +1 more source

MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells

Immunology, EarlyView.
This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si, Gaochen Zhu, Qianling Jiang, Xin Ma, Guan Yang   +4 more
wiley   +1 more source

Activation of FCGR2A enhances the antitumor efficacy of hPSC-derived CAR-M. [PDF]

Front Cell Dev Biol
Yang X, Li L, Zhu S, Li S, Wang X, Han Y, Yang L.   +6 more
europepmc   +1 more source

Interferon Regulatory Factor 2 (IRF2) Suppression Enhances Murine Cardiac Allograft Survival Through Immune Evasion

Immunology, EarlyView.
Our data show that suppressing IRF2, genetically or by siRNA, modulates PD‐L1 and MHC‐I levels. This induced immune‐evasive state critically underlies the significantly prolonged survival of cardiac allografts, revealing a novel therapeutic avenue.
Li Tian, Man Zhang, Yuliang Guo, Sheng Chang, Zhonghua Klaus Chen, Hongmin Zhou   +5 more
wiley   +1 more source

The immunomodulating effect of palmitoylethanolamide on human myeloid dendritic cells and its possible impact on Alzheimer's disease. [PDF]

Front Immunol
Piccolino I, Iannuzzi F, Lionetti L, Mazzonello B, Barreca V, Banaj N, Arezzini V, Piras F, Bossù P.   +8 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Spaceflight alters the immune regulatory functions of neutrophil granulocytes on T lymphocytes. [PDF]

iScience
Tavukçuoğlu E, Yanık H, Güven HE, Yılmaz KB, Esendağlı G.   +4 more
europepmc   +1 more source

Apoptosis kinetics of purified and PBMC‐associated lymphocytes after photopheresis‐like 8‐methoxypsolaren/UVA treatment

Photochemistry and Photobiology, EarlyView.
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde, Imilla Casado Hernandez, Yandy Marx Castillo‐Aleman, Gisela Maria Suarez‐Formigo, Amar Riaz, Antonio Alfonso Bencomo‐Hernandez, Yendry Ventura‐Carmenate   +6 more
wiley   +1 more source

Immunomodulatory effects of primed amniotic fluid-derived mesenchymal stem/stromal cells with IFN-γ from unexplained recurrent miscarriage sources. [PDF]

Sci Rep
Hoseini SM, Bahrami AR, Kalantar SM, Sheikhha MH, Aflatoonian B, Ghasemi N, Hosseini ES, Matin MM, Montazeri F.   +8 more
europepmc   +1 more source