Results 211 to 220 of about 69,003 (290)

CD86 in Dendritic Cell-Mediated Cancer Immunity: From Maturation Marker to Functional Regulator. [PDF]

Biomedicines
Wu TW, Chuang CH, Wu YH.
europepmc   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source

Simultaneous Quantification of Multiple Immune Checkpoint Interactions in Melanoma. [PDF]

J Clin Med
Cacho-Navas C, Camacho L, Agüero J, Batmunkh B, Gracia JM, de Andrea CE, Martín-Algarra S, Rementeria M, Miles J, Gumuzio J, Aguirre F, Parker PJ, Calleja V.   +12 more
europepmc   +1 more source

Efficacy and Safety of Durvalumab and Tremelimumab in Metastatic Non‐Small Cell Lung Cancer: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA 2020 flow diagram of included studies. ABSTRACT Purpose Immune checkpoint inhibitors have transformed treatment strategies for metastatic non‐small cell lung cancer (mNSCLC). This study aimed to assess the efficacy and safety of durvalumab combined with tremelimumab compared with those of standard chemotherapy, particularly in patients with low ...
Ikhwan Rinaldi, Eric Ricardo Yonatan, Tasia Esterita   +2 more
wiley   +1 more source

Local Sodium Tanshinone IIA Sulfonate Attenuates Periodontal Bone Loss by Modulating Inflammatory, Immune and Osteoclastogenic Signalling. [PDF]

J Clin Periodontol
de Molon RS, Scarel-Caminaga RM, Caldeira FID, Ervolino E, de Avila ED, Barbugli PA, Oliveira GE, Franco-Moura JP, Theodoro LH, Cirelli JA, Tetradis S, Kantarci A.   +11 more
europepmc   +1 more source

Integrative Omics Analysis Reveals a CD206+ Macrophage/Dendritic Cell–CD155–TIGIT+ Regulatory T Cell Axis as a Protective Immune Checkpoint Pathway in Atherosclerosis Progression

Barrier Immunity, EarlyView.
ABSTRACT RNA sequencing (RNA‐seq) analysis revealed transcriptional features indicative of sustained immunosuppression within regulatory T cells (Tregs) isolated from atherosclerotic tissues, highlighting the critical contribution of immune checkpoint (ICP) receptor–ligand interactions to atherosclerosis progression. To comprehensively characterize the
Ying Shao, Fatma Saaoud, Mohammed Ben Issa, Keman Xu, Yifan Lu, Shih‐Yu Hung, Juanjuan Liu, Bo Yuan, Juncheng Wei, Sheng Wu, Sadia Mohsin, Zhengjie Zhou, Beata Kosmider, Laisel Martinez, Roberto Vazquez‐Padron, Hong Wang, Xiaofeng Yang   +16 more
wiley   +1 more source

Autosomal recessive human CTLA-4 deficiency with autoimmune infiltration. [PDF]

J Hum Immun
Su HC.
europepmc   +1 more source

Electrochemical Valence‐Regulated Biomimetic Nanozymes for Breast Cancer Metabolism Inhibition and Potentiated Catalytic Immunotherapy

Exploration, EarlyView.
MnOx nanozymes face low tumoricidal activity and PD‐L1‐mediated immune attenuation. Electrochemically regulated M‐MnOx with high oxidase activity was TCM‐wrapped into TMO. TMO targets tumors, triggers ICD, activates cGAS‐STING, antagonizes PD‐L1, and suppresses tumor recurrence, providing new insights for Mn‐based nanomaterials.
You Pan, Wei Cai, Meng Suo, Xiangqin Meng, Shengxin Ye, Yuping Tan, Xianqing Wei, Mingpu Yang, Pengyuan Qi, Zihang Yu, Kelong Fan, Shipeng Ning   +11 more
wiley   +1 more source

Pomalidomide significantly enhances the antitumor immune efficacy of dendritic cell-derived exosomes from multiple myeloma patients. [PDF]

J Transl Med
Zhang H, Wang Y, Wang X, Duan H, Yu D, Kuang X, He L, Zhang W, Chen J, Dai J.   +9 more
europepmc   +1 more source