Results 231 to 240 of about 71,028 (295)

IGF1-IGF1R signaling in tumor-associated macrophages regulates extracellular matrix organization in BRAF inhibitor-targeted melanoma. [PDF]

Mol Cell Biochem
Luo Y, Liu L, Zhou X, Yang J, Tang M, Feng W, Du C, Liu X, Yang L, Liu F, Zhang L.   +10 more
europepmc   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

Allergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan, Xufeng Qu, Carmen Camarena, Araba Abaidoo‐Myles, Parth Naik, Jeremy Allegood, Ankit Kumar, Mihir Pokhriyal, Joseph C. Lownik, Matthew P. Zellner, Grayson W. Way, Jinze Liu, Lauren Ashley Cowart, Stephanie C. Eisenbarth, Joseph W. Landry, Daniel H. Conrad, Rebecca K. Martin   +16 more
wiley   +1 more source

The Microbial Metabolite IDA Sensitizes Tumor Cells to ARF1 Inhibition by Inducing SVIL-dependent Senescence. [PDF]

Int J Biol Sci
Huang M, Wang X, Jiang Y, Li J, Hu B, Wang Y, Hou SX.   +6 more
europepmc   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

Quantitative detection of macrophage activation in osteosarcoma comparing ¹⁸F-FDG PET/CT with ferumoxytol-enhanced MRI. [PDF]

Sci Rep
Roudi R, Habte F, Saladino GM, Vasyliv I, Pisani L, Wong J, Syed A, Daldrup-Link HE.   +7 more
europepmc   +1 more source

Macrophages as Drivers of Resistance to Dabrafenib Plus Trametinib Therapy in Anaplastic Thyroid Cancer. [PDF]

Int J Mol Sci
Rodrigues R, Garcia B, Rito M, Roque R, Pereira T, Morgado S, Tavares V, da Silva TN, Leite V, Cavaco BM.   +9 more
europepmc   +1 more source

Cancer-inspired, chimeric microparticles drive differential modulation of bone marrow-derived dendritic cells and potentiate diverse polarization in T cells.

Mater Adv
Krishna G, Tu AB, Abraham R, Wang Z, Clarke D, Lewis JS.   +5 more
europepmc   +1 more source

AI-Enforced Ultra-Large Virtual Screening Discovers Potent CD28 Binders. [PDF]

J Chem Inf Model
Upadhyay S, Roggia M, Yuan S, Cosconati S, Gabr MT.   +4 more
europepmc   +1 more source

Chirality-Encoded Biomaterials Regulate Local and Systemic Immune Responses in Transplantation. [PDF]

Adv Mater
Lewis HC, Jeffs S, Espinoza A, Goud R, Suarez-Arnedo A, Owusu-Antwi S, Alvarado PC, Segura T.   +7 more
europepmc   +1 more source