Results 31 to 40 of about 25,955 (200)

CD83 expression induced by CpG-DNA stimulation in a macrophage cell line RAW 264.7 [PDF]

BMB Reports, 2013
CpG-DNA has various immunomodulatory effects in dendriticcells, B cells, and macrophages. While induction of cytokinesby CpG-DNA has been well documented in macrophages, theexpression of costimulatory molecules in CpG-DNA treatedmacrophages has not yet ...
Min Chul Park, Dongbum Kim, Younghee Lee, Hyung-Joo Kwon   +3 more
doaj   +1 more source

Inhibition of HIF-1 alpha by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma [PDF]

, 2015
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Acland, Assenat, Bazhin, Carbone, Chaput, Chen, Chouaib, Danenberg, David, Dyson, El-Deiry, Gallick, Gelovani, Ghansah, Giese, Gil, Gress, Gribben, Hao, Hao, Hao, Henson, Jemal, Kiessling, Kroemer, Kroemer, Kroemer, Levi, Luo, Mi, Moses, Plate, Powis, Powis, Powis, Ravichandran, Ricci, Rodeck, Sarker, Schuler, Semenza, Singh, Spisek, Tani, Vandenabeele, Wang, Wang, Zitvogel, Zitvogel, Zitvogel   +49 more
core   +1 more source

IL-18–induced CD83+CCR7+NK helper cells [PDF]

The Journal of Experimental Medicine, 2005
In addition to their cytotoxic activities, natural killer (NK) cells can have immunoregulatory functions. We describe a distinct “helper” differentiation pathway of human CD56+CD3− NK cells into CD56+/CD83+/CCR7+/CD25+ cells that display high migratory responsiveness to lymph node (LN)–associated chemokines, high ability to produce interferon-γ upon ...
Mailliard, Robbie B., Alber, Sean M., Shen, Hongmei, Watkins, Simon C., Kirkwood, John M., Herberman, Ronald B., Kalinski, Pawel   +6 more
openaire   +2 more sources

Inhibition of CD83 Alleviates Systemic Inflammation in Herpes Simplex Virus Type 1-Induced Behçet’s Disease Model Mouse

Mediators of Inflammation, 2019
Behçet’s disease (BD) is an autoinflammatory disease that can lead to life- and sight-threating complications. Dendritic cells (DCs) are the most potent antigen-presenting cells that can regulate multiple inflammatory pathways.
S. M. Shamsul Islam, Hae-Ok Byun, Bunsoon Choi, Seonghyang Sohn   +3 more
doaj   +1 more source

Post-transcriptional regulation of CD83 expression by AUF1 proteins [PDF]

Nucleic Acids Research, 2012
Mature dendritic cells (DC), activated lymphocytes, mononuclear cells and neutrophils express CD83, a surface protein apparently necessary for effective DC-mediated activation of naïve T-cells and T-helper cells, thymic T-cell maturation and the regulation of B-cell activation and homeostasis.
Ehlers, Christina, Schirmer, Susann, Kehlenbach, Ralph H., Hauber, Joachim, Chemnitz, Jan   +4 more
openaire   +3 more sources

CD83 modulates B cell function in vitro: increased IL-10 and reduced Ig secretion by CD83Tg B cells.

PLoS ONE, 2007
The murine transmembrane glycoprotein CD83 is an important regulator for both thymic T cell maturation and peripheral T cell responses. Recently, we reported that CD83 also has a function on B cells: Ubiquitous transgenic (Tg) expression of CD83 ...
Birte Kretschmer, Katja Lüthje, Andreas H Guse, Svenja Ehrlich, Friedrich Koch-Nolte, Friedrich Haag, Bernhard Fleischer, Minka Breloer   +7 more
doaj   +1 more source

Eubacterium rectale Attenuates HSV-1 Induced Systemic Inflammation in Mice by Inhibiting CD83

Frontiers in Immunology, 2021
The purpose of this study was to determine whether administration of the microorganism Eubacterium rectale (E. rectale) could regulate dendritic cell (DC) activation and systemic inflammation in herpes simplex virus type 1-induced Behçet’s disease (BD ...
S. M. Shamsul Islam, Hye-Myung Ryu, Hasan M. Sayeed, Hae-Ok Byun, Ju-Yang Jung, Hyoun-Ah Kim, Chang-Hee Suh, Chang-Hee Suh, Seonghyang Sohn, Seonghyang Sohn   +9 more
doaj   +1 more source

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling [PDF]

, 2008
The kinases MSK1 and MSK2 are activated 'downstream' of the p38 and Erk1/2 mitogen-activated protein kinases. Here we found that MSK1 and MSK2 were needed to limit the production of proinflammatory cytokines in response to stimulation of primary ...
A Cuenda, A Soloaga, A Sommer, Andrew Wingate, B Echtenacher, B Echtenacher, BG Stiles, C Platzer, CA Gogos, Claire E Monk, Claus Johansen, D Rittirsch, DM Dambach, ER Ottosen, F Hildebrand, FY Liew, GR Wiggin, GY Song, H Chi, J Bain, J Darragh, J Han, J Rouse, J Simon C Arthur, Jin Mo Park, JM Park, Joanne Darragh, Joanne McIlrath, JS Arthur, JS Arthur, Julia M Carr, KV Salojin, Lars Iversen, M Brook, M Hammer, M Saraiva, ML Steinhauser, MS Lee, NC Riedamann, NW Freshney, Olga Ananieva, OM Peck-Palmer, P Chen, PC Cheung, PJ Murray, Q Zhao, R Kuhn, Rachel Toth, SE Moreno, SJ O'Keefe, SM Miggin, SQ Latifi, Susana G Santos, T Kawai, T Lang, T van der Poll, VA Beardmore, VS Carl, WJ Hubbard, X Zhang, Y Kalechman, YJ Kang   +61 more
core   +3 more sources

Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells [PDF]

International Immunology, 2000
Human CD83 is a cell surface protein expressed predominantly by dendritic cells (DC) and lymphoid cells. So far, there exists no information on the function and distribution of mCD83. Here we demonstrate that mCD83 is moderately expressed on resting T cells and DC, but strongly increases in its expression on T cells following activation with antigenic ...
S O, Cramer, C, Trumpfheller, U, Mehlhoop, S, Moré, B, Fleischer, A, von Bonin   +5 more
openaire   +2 more sources

A Kinetic Study of CD83 Reveals an Upregulation and Higher Production of sCD83 in Lymphocytes from Pregnant Mice

Frontiers in Immunology, 2017
For the normal development of pregnancy, a balance between immune tolerance and defense is crucial. However, the mechanisms mediating such a balance are not fully understood.
Damián Oscar Muzzio, Katrin Regina Helene Packhäuser, Gleyder Roman-Sosa, Jens Ehrhardt, Diana Krüger, Marek Zygmunt   +5 more
doaj   +1 more source