Results 41 to 50 of about 16,236 (209)

Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells [PDF]

International Immunology, 2000
Human CD83 is a cell surface protein expressed predominantly by dendritic cells (DC) and lymphoid cells. So far, there exists no information on the function and distribution of mCD83. Here we demonstrate that mCD83 is moderately expressed on resting T cells and DC, but strongly increases in its expression on T cells following activation with antigenic ...
S O, Cramer, C, Trumpfheller, U, Mehlhoop, S, Moré, B, Fleischer, A, von Bonin   +5 more
openaire   +2 more sources

CD83 modulates B cell function in vitro: increased IL-10 and reduced Ig secretion by CD83Tg B cells.

PLoS ONE, 2007
The murine transmembrane glycoprotein CD83 is an important regulator for both thymic T cell maturation and peripheral T cell responses. Recently, we reported that CD83 also has a function on B cells: Ubiquitous transgenic (Tg) expression of CD83 ...
Birte Kretschmer, Katja Lüthje, Andreas H Guse, Svenja Ehrlich, Friedrich Koch-Nolte, Friedrich Haag, Bernhard Fleischer, Minka Breloer   +7 more
doaj   +1 more source

Eubacterium rectale Attenuates HSV-1 Induced Systemic Inflammation in Mice by Inhibiting CD83

Frontiers in Immunology, 2021
The purpose of this study was to determine whether administration of the microorganism Eubacterium rectale (E. rectale) could regulate dendritic cell (DC) activation and systemic inflammation in herpes simplex virus type 1-induced Behçet’s disease (BD ...
S. M. Shamsul Islam, Hye-Myung Ryu, Hasan M. Sayeed, Hae-Ok Byun, Ju-Yang Jung, Hyoun-Ah Kim, Chang-Hee Suh, Chang-Hee Suh, Seonghyang Sohn, Seonghyang Sohn   +9 more
doaj   +1 more source

Nonspreading Rift Valley Fever Virus Infection of Human Dendritic Cells Results in Downregulation of CD83 and Full Maturation of Bystander Cells. [PDF]

PLoS ONE, 2015
Vaccines based on nonspreading Rift Valley fever virus (NSR) induce strong humoral and robust cellular immune responses with pronounced Th1 polarisation. The present work was aimed to gain insight into the molecular basis of NSR-mediated immunity. Recent
Nadia Oreshkova, Paul J Wichgers Schreur, Lotte Spel, Rianka P M Vloet, Rob J M Moormann, Marianne Boes, Jeroen Kortekaas   +6 more
doaj   +1 more source

Involvement of Caveolin-1 in CD83 Internalization in Mouse Dendritic Cells

Cell Transplantation, 2015
To become potent T-cell stimulators, DCs need to mature. Treatment with soluble CD83 (sCD83) induces immune tolerance and protects against transplant rejection by maintaining dendritic cells in an immature, tolerogenic state.
Yuejing Yang, Zhongcheng Xin, Jingjia Chu, Na Li, Tao Sun M.D., Ph.D.   +4 more
doaj   +1 more source

Identification of dendritic cell precursor from the CD11c+ cells expressing high levels of MHC class II molecules in the culture of bone marrow with FLT3 ligand

Frontiers in Immunology, 2023
Dendritic cells (DCs) are readily generated from the culture of mouse bone marrow (BM) treated with either granulocyte macrophage-colony stimulating factor (GM-CSF) or FMS-like tyrosine kinase 3 ligand (FLT3L).
Hyunju In, Hyunju In, Ji Soo Park, Ji Soo Park, Hyun Soo Shin, Hyun Soo Shin, Seul Hye Ryu, Seul Hye Ryu, Seul Hye Ryu, Moah Sohn, Moah Sohn, Wanho Choi, Wanho Choi, Sejung Park, Sejung Park, Soomin Hwang, Soomin Hwang, Jeyun Park, Lihua Che, Lihua Che, Tae-Gyun Kim, Min Kyung Chu, Hye Young Na, Hye Young Na, Chae Gyu Park, Chae Gyu Park, Chae Gyu Park   +26 more
doaj   +1 more source

Cutting Edge: CD83 Regulates the Development of Cellular Immunity [PDF]

The Journal of Immunology, 2002
Abstract We recently found that human CD83, a marker of mature dendritic cells, is an adhesion receptor that binds to resting monocytes and a subset of activated CD8+ T cells. We injected CD83-Ig into mice transplanted with the immunogenic P815 mastocytoma and showed that it significantly enhanced the rate of tumor growth and inhibited ...
Nathalie, Scholler, Martha, Hayden-Ledbetter, Amber, Dahlin, Ingegerd, Hellström, Karl Erik, Hellström, Jeffrey A, Ledbetter   +5 more
openaire   +2 more sources

Yupingfeng granules alleviate pediatric asthma by regulating CD83 alternative splicing and reducing serum IgE levels

AIMS Allergy and Immunology
ObjectiveYupingfeng granules (YPFs), a traditional Chinese herbal formulation, have been widely used in managing allergic diseases; yet, their molecular mechanisms remain unclear.
Fang Tang, Jing Huang, Xiaoning Lu, Huasong Zhang   +3 more
doaj   +1 more source

CD83 Modulates B Cell Activation and Germinal Center Responses [PDF]

The Journal of Immunology, 2016
Abstract CD83 is a maturation marker for dendritic cells. In the B cell lineage, CD83 is expressed especially on activated B cells and on light zone B cells during the germinal center (GC) reaction. The function of CD83 during GC responses is unclear.
Lena Krzyzak, Christine Seitz, Anne Urbat, Stefan Hutzler, Christian Ostalecki, Joachim Gläsner, Andreas Hiergeist, André Gessner, Thomas H Winkler, Alexander Steinkasserer, Lars Nitschke   +10 more
openaire   +2 more sources

Endogenous Expression of the Human CD83 Attenuates EAE Symptoms in Humanized Transgenic Mice and Increases the Activity of Regulatory T Cells

Frontiers in Immunology, 2019
The CD83 is a type I membrane protein and part of the immunoglobulin superfamily of receptors. CD83 is involved in the regulation of antigen presentation and dendritic cell dependent allogeneic T cell proliferation.
Elisabeth Zinser, Ronald Naumann, Andreas B. Wild, Julia Michalski, Andrea Deinzer, Lena Stich, Christine Kuhnt, Alexander Steinkasserer, Ilka Knippertz   +8 more
doaj   +1 more source