Results 111 to 120 of about 29,264 (228)

Artonol B and Sikloartobilosanton dari Artocarpus teysmanii MIQ

Journal of Mathematical and Fundamental Sciences, 2019
Dua senyawa masing-masing turunan santon lakton, yaitu artonol B (1) dan turunan furanodihidrobenzosanton, yakni Sikloartobilosanton (2), telah ditemukan pada tumbuhan Artocarpus teysmanii Miq.
Lukman Makmur, Syamsurizal Syamsurizal, Tukiran Tukiran, Yoharmus Syamsu, Sjamsul Arifin Achmad, Euis Holisotan Hakim, Didin Mujahidin, Norio Aimi, Mariko Kitajima, Hiromitsu Takayama   +9 more
doaj  

Oncogenic Mutations and Tumor Microenvironment Alterations in Diffuse Large B‐Cell Lymphoma With Bulky Disease

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Bulky disease represents a clinically aggressive subset of diffuse large B‐cell lymphoma (DLBCL) associated with adverse clinical outcomes. The aim of this study was to investigate the influence of oncogenic mutations and tumor microenvironment alterations on bulky disease in DLBCL.
Yu‐Qing Wang, Yue Wang, Zhi‐Shan Du, Xin‐Yun Huang, Yan Dong, Shuang Tian, Di Fu, Shu Cheng, Li Wang, Peng‐Peng Xu, Sheng‐Jin Fan, Shu‐Ye Wang   +11 more
wiley   +1 more source

Cdc2 kinase

, 1997
During larval development, Drosophila imaginal discs increase in size about 1000-fold and cells are instructed to acquire distinct fates as a function of their position.
Weigmann, K., Lehner, C., Stephen M. Cohen, Christian F. Lehner, Katrin Weigmann, Cohen, S.   +5 more
core   +1 more source

Investigation of CDC2-independent mitotic protein kinases

, 1997
Mitosis is a highly coordinated event which ensures the equal segregation of the cytoplasmic and genetic material into two daughter cells. A key regulatory process in ensuring the temporal fidelity of mitosis involves reversible protein phosphorylation
Gowdy, Patrick Michael
core   +1 more source

Single‐Cell Transcriptome of Anaplastic Thyroid Cancer Reveals Immunosuppressive Tumor Microenvironment Remodeling

Cancer Medicine, Volume 15, Issue 9, September 2026.
Single‐cell RNA sequencing of anaplastic thyroid cancer (ATC) and aggressive papillary thyroid cancer (PTC) revealed coordinated tumor‐intrinsic and immune reprogramming during thyroid cancer dedifferentiation. ATC exhibited MAPK/PI3K co‐activation, p53 suppression, E2F activation, cytotoxic lymphocyte exhaustion, enhanced regulatory T‐cell ...
Saeko Tahara, Akiko Iguchi‐Manaka, Naoto Takeuchi, Tomohei Matsuo, Akira Shibuya, Kazuko Shibuya, Haruka Ozaki   +6 more
wiley   +1 more source

TGF-B1 induces apoptosis through cdc2 activation.

, 2014
A, FACS analyses showed that the sub-G1 phase HuH7 cell population increased from approximately 0.7% to 7.7%, and cells in the G1 phase increased from approximately 69% to 87% 48 h after TGF-β1 treatment. Data represent the means ± S.D.
Tomomi Kogiso (588185), Hikaru Nagahara (588186), Etsuko Hashimoto (158662), Keiko Shiratori (588189), Masakazu Yamamoto (588188), Shunichi Ariizumi (588187)   +5 more
core   +1 more source

TMEM59L promotes neuroendocrine differentiation and enzalutamide resistance in prostate cancer by regulating MUC1/β‐catenin/MYC axis

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Enzalutamide‐mediated AR suppression induces TMEM59L during prostate cancer progression. TMEM59L interacts with MUC1 and promotes its nuclear enrichment. Nuclear MUC1 activates β‐catenin/TCF4‐dependent MYC signalling, driving neuroendocrine differentiation, stemness and EMT.
Xiuchen Guo, Yifan Liu, Jiacheng Huang, Zhiwei Chen, Haihong Liao, Yulin Xu, Xingang Cui, Yongjiang Yu   +7 more
wiley   +1 more source

Erianin inhibits proliferation of activated T cells by downregulating CyclinB1

陆军军医大学学报
Objective To investigate the inhibitory effect of erianin on T cell proliferation and its underlying mechanism. Methods Peripheral blood mononuclear cells (PBMCs) were isolated using density gradient centrifugation, and T cells were purified by ...
JING Lin, ZHANG Ting, LUO Xinyan
doaj   +1 more source

High‐dimensional spectral flow cytometry uncovers progressive T‐cell exhaustion and myeloid cell reprogramming in a CLL mouse model

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Chronic lymphocytic leukemia (CLL) exhibits marked clinical heterogeneity that cannot be fully explained by genetic alterations, underscoring the critical role of the tumor microenvironment in disease progression and therapeutic resistance.
Hannah Briesch, Mariana Coelho, Alessia Floerchinger, Yuliia Borysovych, Nicolas Aubert, Daniel Medina‐Gil, Manina Breitinger, Marc Zapatka, Stella E. Autenrieth, Martina Seiffert   +9 more
wiley   +1 more source

cDC2 subsets [PDF]

Nature Immunology, 2019
openaire   +2 more sources