Results 211 to 220 of about 72,294 (253)

Design, synthesis, anticancer activity, and mechanistic investigation of 4,5,6,7-tetrahydrobenzo[<i>b</i>]thiophene carboxamides as CDK-2 inhibitors: <i>in vitro</i> and <i>in silico</i> DFT and molecular docking study. [PDF]

J Enzyme Inhib Med Chem
Anwer KE, Ramadan RM, Nossier ES, Altwaijry NA, Saleh A, Bräse S, Husseiny EM.   +6 more
europepmc   +1 more source

The Sleeping Giant: Metabolism and Autophagy in the Generation and Survival of Dormant Polyploid Giant Cancer Cells

MedComm, Volume 7, Issue 10, October 2026.
Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna, María Teresa Sánchez‐Montero, Alejandra Díaz‐Chacón, Antonio Rodríguez‐Ariza   +3 more
wiley   +1 more source

Atherosclerosis: Molecular Pathogenesis and Therapeutic Interventions. [PDF]

MedComm (2020)
Kaszubski J, Wawrzyniak A, Gagat M, Żuryń A.   +3 more
europepmc   +1 more source

Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang, Ruomeng Li, Chuanjiang Yu, Jing Li, Xikun Zhou   +4 more
wiley   +1 more source

Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues. [PDF]

Sci Adv
Ng K, Sebaa H, Hirani N, Chizh A, Messi Z, Bland T, Sugioka K, Goehring NW.   +7 more
europepmc   +1 more source

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

The Journal of Pathology, Volume 270, Issue 2, Page 139-162, October 2026.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi, Irene Torresan, Emilio Francesco Giunta, Sara Bleve, Nicole Brighi, Elisa Tassinari, Sofia Zanuccoli, Maria Concetta Cursano, Cristian Lolli   +8 more
wiley   +1 more source

Senolytic Interventions Enhance the Anti-metastatic Activity of Chemotherapy in Prostate Cancer. [PDF]

Cancer Res
Zhou L, Murphy KC, Giwa HK, Hu K, Ma B, Brassil ML, Chang EH, DeMarco KD, Pradhan AJ, Sroka EM, Parikh CN, Mori H, Zhu LJ, Kelliher MA, Ruscetti M.   +14 more
europepmc   +1 more source

Multifactorial Role of Phytogenic CeO2 NPs in Crop Improvement and Stress Alleviation: A Mechanistic Overview

Plant-Environment Interactions, Volume 7, Issue 5, October 2026.
The graphical abstract illustrates how CeO2 nanoparticles help plants withstand biotic and abiotic stresses. Their application reduces excessive ROS through enhanced antioxidant defenses, whereas modulating stress signaling, phytohormones, and gene expression.
Faiza Arooj, Khafsa Malik, Tahira Sultana, Abeer Kazmi, Md. Fakhrul Islam, Rafia Azam, Munaza Iram   +6 more
wiley   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, Volume 40, Issue 10, Page 6005-6042, October 2026.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

G0 or no-G0: phosphatase control of quiescence and cell cycle entry. [PDF]

Biochem Soc Trans
Robinson EA, Barr AR.
europepmc   +1 more source