Results 21 to 30 of about 137,554 (368)
Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates [PDF]
Science, 2007 In budding yeast, phosphate starvation triggers inhibition of the Pho80-Pho85 cyclin–cyclin-dependent kinase (CDK) complex by the CDK inhibitor Pho81, leading to expression of genes involved in nutrient homeostasis. We isolated myo - d -inositol heptakisphosphate (IP 7
Sashidhar Mulugu +3 more
openaire +3 more sources
Aaptamine attenuates the proliferation and progression of non-small cell lung carcinoma
Pharmaceutical Biology, 2020 Context Aaptamine is a potent ocean-derived non-traditional drug candidate against human cancers. However, the underlying molecular mechanisms governing aaptamine-mediated repression of lung cancer cells remain largely undefined. Objective To examine the
Kaikai Gong +8 more
doaj +1 more source
CDK inhibitors: positive and negative regulators of G1-phase progression.
Genes & Development, 1999 Mitogen-dependent progression through the first gap phase (G1) and initiation of DNA synthesis (S phase) during the mammalian cell division cycle are cooperatively regulated by several classes of cyclin-dependent kinases (CDKs) whose activities are in ...
C. Sherr, James M. Roberts
semanticscholar +1 more source
Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication [PDF]
, 2011 Treslin, a TopBP1-interacting protein, is necessary for deoxyribonucleic acid (DNA) replication in vertebrates. Association between Treslin and TopBP1 requires cyclin-dependent kinase (Cdk) activity in Xenopus laevis egg extracts.
Dunphy, William G. +3 more
core +2 more sources
A conserved but plant-specific CDK-mediated regulation of DNA replication protein A2 in the precise control of stomatal terminal division [PDF]
, 2019 The R2R3-MYB transcription factor FOUR LIPS (FLP) controls the stomatal terminal division through transcriptional repression of the cell cycle genes CYCLIN-DEPENDENT KINASE (CDK) B1s (CDKB1s), CDKA; 1, and CYCLIN A2s (CYCA2s).
Dong, Juan +8 more
core +2 more sources
Cyclin D2 Interacts with cdk‐5 and Modulates Cellular cdk‐5/p35 Activity [PDF]
Journal of Neurochemistry, 1998 Abstract: Cyclin‐dependent kinase‐5 (cdk‐5) is a serine/threonine kinase that displays neurone‐specific activity. Experimental manipulation of cdk‐5 expression in neurones has shown that cdk‐5 is essential for proper development of the nervous system and, in particular, for outgrowth of neurites.
Sonia Guidato +3 more
openalex +4 more sources
Studia Mythologica Slavica, 2019 In 1973, Ivanov and Toporov developed an attempted reconstruction of the presumably central theme of ancient Slavic mythology, viz. the cosmic battle between the thunder-god Perunъ and his adversary Volosъ the cattle god, modelled after the analogous ...
Milorad Ivanković
doaj +1 more source
Asynchronous nuclear division cycles in multinucleated cells [PDF]
, 2006 Synchronous mitosis is common in multinucleated cells. We analyzed a unique asynchronous nuclear division cycle in a multinucleated filamentous fungus, Ashbya gossypii.
Gladfelter, A. S. +2 more
core +2 more sources
BMC Genomics, 2021 Background Cyclin-dependent kinases (CDKs) are protein kinases regulating important cellular processes such as cell cycle and transcription. Many CDK genes also play a critical role during adipogenic differentiation, but the role of CDK gene family in ...
Cuili Pan +8 more
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The Role Of Time Delays, Slow Processes And Chaos In Modulating The Cell-Cycle Clock
Mathematical Biosciences and Engineering, 2005 The regulation of the cell cycle clock is examined using a theoretical model for the embryonic cell cycle, where the clock is described as a single-limit cycle [1].
E.V. Presnov, Z. Agur
doaj +1 more source