Results 231 to 240 of about 67,859 (329)
The Cdk1 Complex Plays a Prime Role in Regulating N-Myc Phosphorylation and Turnover in Neural Precursors [PDF]
Sarah K. Sjostrom+4 more
openalex +1 more source
ABSTRACT A cellular characteristic of IPF is the transformation of fibrosis into myofibroblasts. This study identifies several transcription factors—STAT3, FOXP1, JUNB, ATF3, FosL2, BATF, Fra2 and AP‐1—that play crucial roles in promoting pulmonary fibrogenesis.
Yujie Wang+9 more
wiley +1 more source
CDK1: beyond cell cycle regulation
Songmin Ying, Hongwei Liao, Fang Ji
openaire +3 more sources
Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis [PDF]
Tomoya Yamaguchi+9 more
openalex +1 more source
Multi‐Omic Analysis of Glutamate Excitotoxicity in Primary Neuronal Cultures
Our study on rat neuron cells found 250 μM glutamate to be toxic, causing neuron death. We identified genes in pathways linked to apoptosis, neuron plasticity, and cell signaling, along with proteins regulating the cell cycle and tumor proliferation.
Jennifer H. Nguyen+13 more
wiley +1 more source
Over‐expression of Aurora‐A targets cytoplasmic polyadenylation element binding protein and promotes mRNA polyadenylation of Cdk1 and cyclin B1 [PDF]
Takashi Sasayama+7 more
openalex +1 more source
ABSTRACT For human and canine invasive urothelial carcinoma (InvUC), there is growing interest in using the molecular characteristics of a tumour to guide individualised treatment strategies. The objective of this study was to use a non‐invasive, urine‐based method to characterise gene expression signatures in dogs with InvUC.
Ellen Marie Kuerbitz+6 more
wiley +1 more source
Chromosome bridge resolution during mitosis is influenced by the length of the bridging chromatin. Using CRISPR/Cas9, we engineered chromosome bridges with precisely defined intercentromeric distances. Results on the progression of these bridges during mitosis revealed that longer bridges require greater kinetochore separation to break than shorter ...
Teresa Anglada+3 more
wiley +1 more source