Results 231 to 240 of about 67,859 (329)

The Cdk1 Complex Plays a Prime Role in Regulating N-Myc Phosphorylation and Turnover in Neural Precursors [PDF]

open access: bronze, 2005
Sarah K. Sjostrom   +4 more
openalex   +1 more source

STAT3 Facilitates Super Enhancer Formation to Promote Fibroblast‐To‐Myofibroblast Differentiation by the Analysis of ATAC‐Seq, RNA‐Seq and ChIP‐Seq

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 11, June 2025.
ABSTRACT A cellular characteristic of IPF is the transformation of fibrosis into myofibroblasts. This study identifies several transcription factors—STAT3, FOXP1, JUNB, ATF3, FosL2, BATF, Fra2 and AP‐1—that play crucial roles in promoting pulmonary fibrogenesis.
Yujie Wang   +9 more
wiley   +1 more source

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis [PDF]

open access: bronze, 2005
Tomoya Yamaguchi   +9 more
openalex   +1 more source

Multi‐Omic Analysis of Glutamate Excitotoxicity in Primary Neuronal Cultures

open access: yesJournal of Neurochemistry, Volume 169, Issue 6, June 2025.
Our study on rat neuron cells found 250 μM glutamate to be toxic, causing neuron death. We identified genes in pathways linked to apoptosis, neuron plasticity, and cell signaling, along with proteins regulating the cell cycle and tumor proliferation.
Jennifer H. Nguyen   +13 more
wiley   +1 more source

Over‐expression of Aurora‐A targets cytoplasmic polyadenylation element binding protein and promotes mRNA polyadenylation of Cdk1 and cyclin B1 [PDF]

open access: bronze, 2005
Takashi Sasayama   +7 more
openalex   +1 more source

Characterisation of Gene Expression in Canine Invasive Urothelial Carcinoma Using a NanoString‐Based Urine Assay

open access: yesVeterinary and Comparative Oncology, Volume 23, Issue 2, Page 205-215, June 2025.
ABSTRACT For human and canine invasive urothelial carcinoma (InvUC), there is growing interest in using the molecular characteristics of a tumour to guide individualised treatment strategies. The objective of this study was to use a non‐invasive, urine‐based method to characterise gene expression signatures in dogs with InvUC.
Ellen Marie Kuerbitz   +6 more
wiley   +1 more source

Engineering Chromosome Bridges Through CRISPR/Cas9 to Decipher the Impact of Intercentromeric Distance on Resolution Dynamics

open access: yesThe FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Chromosome bridge resolution during mitosis is influenced by the length of the bridging chromatin. Using CRISPR/Cas9, we engineered chromosome bridges with precisely defined intercentromeric distances. Results on the progression of these bridges during mitosis revealed that longer bridges require greater kinetochore separation to break than shorter ...
Teresa Anglada   +3 more
wiley   +1 more source

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