Results 221 to 230 of about 74,242 (343)

Phosphorylation of Threonine 61 by Cyclin A/Cdk1 Triggers Degradation of Stem-Loop Binding Protein at the End of S Phase

, 2008
M. Murat Köseoğlu, Lee M. Graves, William F. Marzluff   +2 more
openalex   +2 more sources

Cell cycle follows ‘pause and play’ mechanism in salt and cold stress recovery in diverse plant species

New Phytologist, Volume 250, Issue 3, Page 1689-1703, May 2026.
Summary Changes to organismal growth induced by environmental stress are orchestrated at the cellular level. These periods of stress may be followed by recovery periods, when plants have the opportunity to return to normal growth conditions. However, the cell cycle mechanisms underlying recovery are poorly understood.
Olivia S. Hazelwood, Kamryn A. Diehl, Vicky Hollenbeck, Joh Demura‐Devore, Dustin Herb, Joseph P. Gallagher, M. Arif Ashraf   +6 more
wiley   +1 more source

CDK1 inhibition reduces osteogenesis in endothelial cells in vascular calcification

JCI Insight
Vascular calcification is a severe complication of cardiovascular diseases. Previous studies demonstrated that endothelial lineage cells transitioned into osteoblast-like cells and contributed to vascular calcification.
Yan Zhao, Yang Yang, Xiuju Wu, Li Zhang, Xinjiang Cai, Jaden Ji, Sydney Chen, Abigail Vera, Kristina I. Boström, Yucheng Yao   +9 more
doaj   +1 more source

Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration

, 2011
Rong Chu, David Terrano, Timothy C. Chambers   +2 more
openalex   +2 more sources

Supplementary Figure 1 from CDK1 Phosphorylation of YAP Promotes Mitotic Defects and Cell Motility and Is Essential for Neoplastic Transformation [PDF]

, 2023
Shuping Yang, Lin Zhang, Miao Liu, Rong Chong, Shi‐Jian Ding, Yuanhong Chen, Jixin Dong   +6 more
openalex   +1 more source

CSPG4 Mediates Inflammatory, Cell Death, and Senescence Responses in Enteric Glia Exposed to Clostridioides difficile Toxins

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Enteric glia in humans, mice, and rats express all known receptors for TcdA (LDLR) and TcdB (CSPG4, FZD‐1, FZD2, FZD7, PVRL3, TFPI, LRP1). CSPG4 expression is increased in colonic tissues from humans and mice with C. difficile infection, as well as in rat enteric glia exposed to TcdA or TcdB. C.
Francisco M. S. Marques, Deiziane V. S. Costa, Conceição S. M. Rebouças, Gerly A. C. Brito, Cirle A. Warren, Renata F. C. Leitão   +5 more
wiley   +1 more source

The Binding of 3‐O‐Methylfluorescein Phosphate to the Catalytic Domain of the Human CDC25B Phosphatase: A Structural Investigation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Structural studies on the complex that CDC25B C473S (CDC25B‐S) forms with the 3‐O‐methylfluorescein phosphate (3‐OMFP) reveal how the fluorogenic substrate binds CDC25B‐S, engaging key binding regions and inducing structural adjustments that stabilize the protein.
Romualdo Troisi, Rosario Rullo, Valeria Napolitano, Grzegorz M. Popowicz, Emmanuele De Vendittis, Filomena Sica   +5 more
wiley   +1 more source

Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer [PDF]

, 2017
Xiaming Liu, Yanfei Gao, HuiHui Ye, Sean Gerrin, Fen Ma, Yiming Wu, Tengfei Zhang, Joshua W. Russo, Changmeng Cai, Xin Yuan, Jihong Liu, Shaoyong Chen, Steven P. Balk   +12 more
openalex   +1 more source

The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia, Michael Kapsalis, Michael Georgoulakis, Athanasios Panousis, Constantinos G. Neochoritis   +4 more
wiley   +1 more source

Sequential Cdk1 and Plk1 phosphorylation of caspase‐8 triggers apoptotic cell death during mitosis [PDF]

, 2014
Yves Matthess, Monika Raab, Rainald Knecht, Sven Becker, Klaus Strebhardt   +4 more
openalex   +1 more source