Results 201 to 210 of about 74,242 (343)

CDK1: beyond cell cycle regulation

open access: yesAging, 2017
Liao, Hongwei, Ji, Fang, Ying, Songmin
openaire   +2 more sources

CDK1 phosphorylation of TAZ in mitosis inhibits its oncogenic activity [PDF]

open access: diamond, 2015
Lin Zhang   +5 more
openalex   +1 more source

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu   +6 more
wiley   +1 more source

Cell division responsive peptides for optimized plasmid DNA delivery : the mitotic window of opportunity? [PDF]

open access: yes, 2014
De Smedt, Stefaan   +4 more
core   +1 more source

Saikosaponin A Inhibits Migration/Invasion and Triggers Cell‐Cycle Arrest and Autophagy‐Induced Cell Death in HCT116 Cells and In Vivo

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
Saikosaponin A from Radix Bupleuri inhibited colorectal cancer HCT116 cells with low toxicity. SSA induced S/G2‐M cell cycle arrest and triggered autophagy via mTOR inhibition. SSA suppressed metastasis by blocking PI3K/AKT signaling pathway. SSA significantly reduced tumor growth without apparent toxicity.
Xiu‐Xiu Zhang   +7 more
wiley   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao   +7 more
wiley   +1 more source

Suppressing CDCA8/CDK1 improves oral squamous cell carcinoma by modulating proliferation, apoptosis, cell cycle and migration

open access: yesDiscover Oncology
We aimed to clarify the role of CDCA8/CDK1 in the progression of oral squamous cell carcinoma (OSCC) and the potential mechanisms. To explore the CDCA8 expression in OSCC, clinical samples were collected.
Jiang Zhu   +6 more
doaj   +1 more source

CDK1 Inhibition Targets the p53-NOXA-MCL1 Axis, Selectively Kills Embryonic Stem Cells, and Prevents Teratoma Formation [PDF]

open access: gold, 2015
Noelle E. Huskey   +10 more
openalex   +1 more source

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