Results 211 to 220 of about 74,242 (343)

Evaluating Protein Enrichment Methods to Improve Biomarker Discovery in Equine Cerebrospinal Fluid

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Here, we compared two protein enrichment methods—ProteoMiner Small‐Capacity and PreOmics Enrich‐iST—for proteomic analysis of equine cerebrospinal fluid (CSF). PreOmics Enrich‐iST achieved superior depletion of high‐abundance proteins and identified a greater number of low‐abundance, neuropathology‐relevant proteins than ProteoMiner or native digestion.
Foti Federico   +5 more
wiley   +1 more source

CARM1 S217 phosphorylation by CDK1 in late G2 phase facilitates mitotic entry

open access: yesCell Death and Disease
The coactivator-associated arginine methyltransferase 1 (CARM1) functions as an epigenetic writer, however, its role in mitosis remains poorly understood.
Yena Cho   +3 more
doaj   +1 more source

Supplementary Figure 7 from Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair

open access: gold, 2023
Dongping Wei   +10 more
openalex   +1 more source

Predictive Value of Circulating Tumor Cells in Neoadjuvant Chemoimmunotherapy for Non‐Small Cell Lung Cancer

open access: yesThoracic Cancer, Volume 17, Issue 9, May 2026.
Preoperative CK+ CTC monitoring may serve as a promising adjunct to conventional imaging for predicting pathological response in patients receiving neoadjuvant chemoimmunotherapy. Our exploratory findings suggest that systemic CTC dissemination is associated with a microenvironmental convergence of local hypoxia and attenuated immune signaling ...
Jianyi Yang   +11 more
wiley   +1 more source

SIRT1 Downregulation by Advanced Glycation End Products Activates RANKL‐Dependent Osteoclast Signaling and Drives Chondrocyte Senescence During Osteoarthritis Development

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Mechanistic study of AGEs‐induced OA progression via SIRT1/RANKL/RANK signaling‐mediated osteoclast–chondrocyte communication and cellular senescence. ABSTRACT Advanced glycation end products (AGEs) accumulate with aging and metabolic stress and are increasingly implicated in osteoarthritis (OA) pathology.
Yizhou Li   +4 more
wiley   +1 more source

Grapes(Chk1) prevents nuclear CDK1 activation by delaying cyclin B nuclear accumulation [PDF]

open access: bronze, 2008
Anne Royou   +3 more
openalex   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska   +2 more
wiley   +1 more source

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